Segesterone

Segesterone acetate, also known as SA or Nestorone, is a progestin medication which is used in birth control for women. It is available in combination with estrogen as a vaginal ring or skin patch. It is also used in the form of an implant for the treatment of endometriosis.

Pharmacology

Segesterone acetate is a progestogen, or an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has no other hormonal activity.

Medical uses

Segesterone acetate is used in combination with ethinylestradiol (an estrogen) in contraceptive vaginal rings and contraceptive patches. It is also used alone as a contraceptive implant.

Side effects

The side effects of segesterone acetate are similar to those of other progestins. They can include menstrual irregularities, headache, breast tenderness, mood changes, and others.

History

Segesterone acetate was developed by the Population Council, a non-profit organization in the United States that conducts research into reproductive health. It was first described in the literature in 1983 and was introduced for medical use in 2003.

See also

• List of progestogens
• List of progestogen esters

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