AB-CHFUPYCA

Synthetic cannabinoid

{{Drugbox | verifiedfields = changed | verifiedrevid = 477002123 | IUPAC_name = N-[[1-(cyclohexylmethyl)-1H-indol-3-yl]carbonyl]-1,1-difluoropentylamine | image = AB-CHFUPYCA_chemical_structure.png | width = 200 }}

AB-CHFUPYCA is a synthetic cannabinoid that has been used in scientific research and is a potent agonist of the cannabinoid receptors. It is structurally related to other synthetic cannabinoids such as AB-FUBINACA and AB-PINACA.

Chemical structure

AB-CHFUPYCA is classified as an indole-based synthetic cannabinoid. Its chemical structure includes a 1-(cyclohexylmethyl)-1H-indole core, which is linked to a 1,1-difluoropentyl side chain. The presence of the cyclohexylmethyl group and the difluoropentyl chain are characteristic features that influence its binding affinity and activity at cannabinoid receptors.

Pharmacology

AB-CHFUPYCA acts as a potent agonist at the CB₁ and CB₂ receptors, which are part of the endocannabinoid system. This system is involved in regulating various physiological processes including mood, memory, appetite, and pain sensation. The activation of these receptors by AB-CHFUPYCA can lead to effects similar to those produced by tetrahydrocannabinol (THC), the active component of cannabis.

Legal status

The legal status of AB-CHFUPYCA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is often included in legislation targeting synthetic cannabinoids and "designer drugs."

Potential risks and side effects

As with other synthetic cannabinoids, the use of AB-CHFUPYCA can pose significant health risks. These may include tachycardia, hypertension, hallucinations, and psychosis. The variability in potency and the lack of quality control in illicit preparations further increase the risk of adverse effects.

Research and applications

AB-CHFUPYCA is primarily used in scientific research to study the endocannabinoid system and to develop new therapeutic agents. Its potent activity at cannabinoid receptors makes it a useful tool for understanding receptor function and for screening potential drug candidates.

Related pages

• Synthetic cannabinoids
• Cannabinoid receptor
• Endocannabinoid system
• Designer drugs

Gallery

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  Chemical structure of AB-CHFUPYCA