Abraham Buschke

German dermatologist known for his work on infectious diseases and skin conditions

Abraham Buschke (27 September 1868 – 25 February 1943) was a German dermatologist renowned for his contributions to the understanding of infectious diseases and various skin conditions. He is best known for describing Buschke-Löwenstein tumor and Buschke-Ollendorff syndrome.

Early life and education

Abraham Buschke was born in Nak_o, Province of Posen, which was then part of the Kingdom of Prussia. He pursued his medical studies at the University of Berlin, where he developed a keen interest in dermatology.

Career

Buschke began his medical career at the Charité Hospital in Berlin, where he worked under the mentorship of prominent dermatologists of the time. His work primarily focused on infectious skin diseases, and he made significant contributions to the understanding of syphilis and other sexually transmitted infections.

Buschke-Löwenstein tumor

One of Buschke's most notable contributions was the identification and description of the Buschke-Löwenstein tumor, a rare form of verrucous carcinoma that affects the anogenital region. This condition is characterized by its large, cauliflower-like growths and is associated with human papillomavirus (HPV) infection.

Buschke-Ollendorff syndrome

Buschke also co-described Buschke-Ollendorff syndrome, a rare genetic disorder characterized by the presence of dermatofibrosis lenticularis disseminata and osteopoikilosis. This syndrome is inherited in an autosomal dominant pattern and is associated with mutations in the LEMD3 gene.

Later life and legacy

In 1933, due to the rise of the Nazi regime and its anti-Semitic policies, Buschke was forced to leave his position at the Charité Hospital. He emigrated to the United States, where he continued his work in dermatology until his death in 1943.

Buschke's contributions to dermatology have had a lasting impact, and his name is still associated with the conditions he described. His work laid the foundation for further research into the diagnosis and treatment of complex skin diseases.

Related pages

• Buschke-Löwenstein tumor
• Buschke-Ollendorff syndrome
• Dermatology
• Human papillomavirus

Gallery

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  Abraham Buschke