Erythema gyratum repens

Erythema gyratum repens
Synonyms	EGR
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Erythema gyratum repens (EGR) is a rare paraneoplastic syndrome characterized by distinctive skin changes. It is often associated with underlying malignancy, particularly lung cancer.

Presentation

Erythema gyratum repens is marked by rapidly evolving erythematous rashes that form concentric, wood-grain-like patterns on the skin. These lesions are typically pruritic and can cover large areas of the body. The rash is known for its unique appearance and rapid progression.

Associated Conditions

EGR is most commonly associated with lung cancer, but it can also be linked to other types of cancer such as breast cancer, esophageal cancer, and stomach cancer. In some cases, EGR may precede the diagnosis of the underlying malignancy, making it an important clinical sign for early detection.

Diagnosis

The diagnosis of erythema gyratum repens is primarily clinical, based on the characteristic appearance of the rash. A thorough medical history and physical examination are essential. Skin biopsy may be performed to rule out other conditions. Additionally, screening for underlying malignancies is crucial once EGR is suspected.

Treatment

The primary approach to managing erythema gyratum repens involves treating the underlying malignancy. Successful treatment of the associated cancer often leads to resolution of the skin lesions. Symptomatic treatment for the rash may include topical corticosteroids and antihistamines to alleviate itching.

Prognosis

The prognosis of erythema gyratum repens largely depends on the underlying malignancy. Early detection and treatment of the associated cancer can improve outcomes. The skin manifestations typically resolve once the malignancy is addressed.

See also

• Paraneoplastic syndrome
• Dermatology
• Lung cancer

External links

• DermNet NZ: Erythema gyratum repens