Fosazepam

Fosazepam is a benzodiazepine derivative. It is a water-soluble benzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties. Fosazepam is a prodrug for desmethyldiazepam which is responsible for the therapeutic effects of fosazepam.

Pharmacology

Fosazepam acts as a full agonist at the benzodiazepine receptor to produce its range of therapeutic and adverse effects. According to the World Health Organization (WHO), fosazepam is a particularly potent benzodiazepine and is sometimes used as a reference drug for comparing the strength of other benzodiazepines.

Medical uses

Fosazepam is used for the short-term relief of symptoms of anxiety, or anxiety associated with depression. Anxiety or tension associated with the stress of everyday life usually does not require treatment with fosazepam.

Side effects

The most common side effects of fosazepam are drowsiness, dizziness, and light-headedness. These side effects can be more pronounced with increased doses. High doses may also cause fluctuating mood, nausea, headache, and irritability.

Interactions

Fosazepam can interact with a number of other medications, including barbiturates, ethanol, and opioids, which can enhance the sedative effects of fosazepam. It can also interact with antidepressants, antipsychotics, and antihistamines, which can increase the risk of side effects.

See also

• Benzodiazepine
• Desmethyldiazepam
• Anxiety
• Depression

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