Dropropizine
Dropropizine is a cough suppressant, or antitussive, that is commonly used to treat persistent, non-productive coughs. It is a non-opioid medication, meaning it does not contain any substances derived from the opium poppy. Dropropizine works by reducing the activity of the cough center in the brain, thereby reducing the urge to cough.
Pharmacology
Dropropizine's antitussive effects are believed to be due to its direct action on the cough center in the medulla. It is a peripheral antitussive agent with a low incidence of side effects. It is rapidly absorbed from the gastrointestinal tract and has a half-life of 6 to 8 hours.
Medical uses
Dropropizine is used to relieve dry coughs that do not produce any mucus, a condition known as non-productive cough. It is not intended for use in coughs that are accompanied by excessive mucus production.
Side effects
Common side effects of dropropizine include drowsiness, dizziness, and gastrointestinal disturbances such as nausea and vomiting. In rare cases, it can cause allergic reactions such as skin rash, itching, and hives.
Contraindications
Dropropizine should not be used in patients with a known hypersensitivity to the drug. It is also contraindicated in patients with severe liver or kidney disease.
See also
References
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