WAY-100135

WAY-100135 is a compound used in scientific research. It acts as a selective antagonist for the 5-HT1A receptor, and has been used to research the role of this receptor in depression, anxiety, the effects of antidepressant drugs, and drug withdrawal symptoms. WAY-100135 has been found to block the action of the 5-HT1A agonist 8-OH-DPAT, and it has been suggested that it may also have inverse agonist effects at the 5-HT1A receptor.

Pharmacology

WAY-100135 is a selective antagonist for the 5-HT1A receptor. It has been used in scientific research to study the role of this receptor in various conditions, including depression, anxiety, the effects of antidepressant drugs, and drug withdrawal symptoms.

The compound has been found to block the action of the 5-HT1A agonist 8-OH-DPAT. This has led to its use in studies investigating the effects of 5-HT1A agonists and antagonists on behavior and mood.

In addition to its antagonist properties, it has been suggested that WAY-100135 may also have inverse agonist effects at the 5-HT1A receptor. This means that it may not only block the action of 5-HT1A agonists, but also produce effects opposite to those of agonists when administered alone.

Research Uses

WAY-100135 has been used in a variety of research contexts. Its ability to selectively block the 5-HT1A receptor has made it a valuable tool in studies investigating the role of this receptor in depression and anxiety.

The compound has also been used to study the effects of antidepressant drugs. By blocking the action of 5-HT1A agonists, it can help to elucidate the mechanisms by which these drugs exert their effects.

In addition, WAY-100135 has been used to study drug withdrawal symptoms. By blocking the action of 5-HT1A agonists, it can help to understand the role of this receptor in the development of these symptoms.

See Also

• 5-HT1A receptor
• 8-OH-DPAT
• Antidepressant

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