Nilvadipine

Nilvadipine is a calcium channel blocker used for the treatment of hypertension and chronic stable angina. It works by relaxing the muscles of your heart and blood vessels.

Mechanism of Action

Nilvadipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle. It suppresses the calcium-dependent contraction of the vascular smooth muscle and dilates the coronary arteries and systemic arteries, thereby reducing blood pressure and myocardial oxygen consumption.

Indications

Nilvadipine is indicated for the treatment of hypertension and chronic stable angina.

Side Effects

Common side effects of Nilvadipine include headache, flushing, dizziness, and palpitations. Serious side effects may include low blood pressure, heart failure, and arrhythmias.

Contraindications

Nilvadipine is contraindicated in patients with known hypersensitivity to Nilvadipine or any other dihydropyridine.

Drug Interactions

Nilvadipine may interact with other drugs such as beta blockers, digoxin, and cimetidine.

Dosage and Administration

The usual starting dose of Nilvadipine is 8 mg once daily. The dose may be increased to a maximum of 16 mg once daily, based on patient response and tolerability.

See Also

• Calcium channel blocker
• Hypertension
• Angina

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