Erythema gyratum repens

Erythema Gyratum Repens

File:Erythema gyratum repens.jpg

Erythema gyratum repens

Erythema gyratum repens (EGR) is a rare dermatological condition, characterized by distinctive, concentric, erythematous bands that spread in a serpiginous, or gyrate, fashion. It is often associated with internal malignancies, particularly lung cancer and esophageal cancer.

Etiology

The exact cause of EGR is unknown. However, it is often associated with internal malignancies, particularly lung and esophageal cancers. Other associated malignancies include breast cancer, stomach cancer, and bladder cancer. EGR has also been reported in association with HIV infection and tuberculosis.

Clinical Presentation

EGR presents as concentric, erythematous bands that spread in a serpiginous, or gyrate, fashion. The bands are typically 1-2 cm in width and can cover large areas of the body. The rash is often pruritic, or itchy, and may be accompanied by systemic symptoms such as fever, weight loss, and malaise.

Diagnosis

Diagnosis of EGR is primarily clinical, based on the characteristic appearance of the rash. However, a skin biopsy may be performed to rule out other conditions. In addition, patients with EGR should undergo a thorough evaluation for underlying malignancy, as the rash is often a paraneoplastic phenomenon.

Treatment

Treatment of EGR involves addressing the underlying malignancy, if present. Topical corticosteroids may be used to alleviate symptoms of the rash. In some cases, the rash may resolve spontaneously once the underlying malignancy is treated.

Prognosis

The prognosis of EGR is largely dependent on the underlying malignancy. If the malignancy is treatable, the rash often resolves. However, if the malignancy is advanced, the rash may persist despite treatment.

See Also

• Paraneoplastic syndromes
• Dermatology
• Lung cancer
• Esophageal cancer