Conjugated linoleic acid
Conjugated Linoleic Acids (CLA)
Introduction
Conjugated Linoleic Acids (CLA) are a family of fatty acids that are isomers of linoleic acid. Found predominantly in meat and dairy products derived from ruminants, CLAs have attracted interest for their potential health benefits and are widely marketed as dietary supplements.
Chemical Structure
CLA refers to a group of at least 28 isomers of linoleic acid, characterized by:
- Conjugated Double Bonds: Their two double bonds are conjugated, meaning they are separated by a single bond.
- Cis and Trans Forms: CLAs can exist in both cis and trans forms, affecting their structure and potential biological activities.
Sources of CLA
Natural sources of CLA include:
- Ruminant Meat: Such as beef and lamb.
- Dairy Products: Including milk, cheese, and butter from cows, goats, and sheep.

Types of CLA Isomers
The most common and well-studied isomers of CLA are:
- C9, T11-CLA: Also known as rumenic acid, predominantly found in natural sources.
- T10, C12-CLA: Often found in dietary supplements.
Potential Health Benefits
CLA has been studied for its potential benefits, including:
- Weight Management: Some studies suggest CLA can reduce body fat.
- Anti-Cancer Properties: Research indicates potential in inhibiting cancer cell growth.
- Cardiovascular Health: CLA may influence cholesterol levels and heart health.
CLA as a Dietary Supplement
CLA is marketed as a supplement with claims of:
- Enhancing weight loss.
- Building muscle.
- Improving health outcomes.
However, the efficacy and safety of CLA supplements are subjects of ongoing research and debate.
Research and Controversies
Research on CLA's health effects is mixed, with some studies showing benefits and others indicating potential adverse effects, particularly with high doses or long-term use.
External Links
- [Link to a scientific review on the health effects of CLA]
- [Link to a nutritional guide discussing CLA in foods]
References
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