Phenobarbital antenatal exposure

Other Names: Phenobarbital embryopathy

A teratologic disorder associated with intrauterine exposure of phenorbarbital during the first trimester of pregnancy. Infants are usually asymptomatic but an increased risk of intellectual disability, tetralogy of Fallot, unilateral cleft lip, hypoplasia of the mitral valve and some other mild abnormalities such as hypertelorism, epicanthus, hypoplasia and low insertion of the nose, low insertion of the ears, prognathism, finger hypoplasia, brachydactyly and hypospadias have been reported in rare cases.

NIH genetic and rare disease info

• NIH info on Phenobarbital antenatal exposure

Phenobarbital antenatal exposure is a rare disease.

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