Phenylephrine/ketorolac

Phenylephrine/Ketorolac

Phenylephrine/Ketorolac is a combination medication used in the field of ophthalmology to maintain pupil size by preventing intraoperative miosis (pupil constriction) and reducing postoperative ocular pain during cataract surgery or intraocular lens replacement.

Composition

This medication is a combination of two active ingredients: Phenylephrine and Ketorolac. Phenylephrine is a selective alpha-1 adrenergic receptor agonist used for dilation of the pupil. It works by constricting the blood vessels in the eye, thereby reducing the amount of fluid that can drain out of the eye. Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain natural substances in your body to reduce pain and swelling.

Indications

Phenylephrine/Ketorolac is indicated for the maintenance of mydriasis (pupil dilation) during cataract surgery or intraocular lens replacement and for the reduction of postoperative ocular pain.

Contraindications

This medication is contraindicated in patients with known hypersensitivity to any of its components, or to other NSAIDs, and in patients with asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

Side Effects

Common side effects of Phenylephrine/Ketorolac include increased intraocular pressure, posterior capsule opacification, eye inflammation, and eye pain. Serious side effects may include slow or uneven heart rate, severe headache, buzzing in your ears, anxiety, confusion, shortness of breath, and severe nausea.

Interactions

Phenylephrine/Ketorolac may interact with other medications, including blood thinners, steroids, and other NSAIDs. It is important to inform your healthcare provider of all medications you are currently taking.

Dosage

The recommended dose of Phenylephrine/Ketorolac is one drop instilled into the affected eye(s) three times in the hour before surgery.

Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Translate this page: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian