Reticular erythematous mucinosis

Reticular Erythematous Mucinosis

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Reticular Erythematous Mucinosis

Reticular erythematous mucinosis (REM) is a rare skin disease characterized by erythematous patches that form a reticular pattern. It was first described by Steigleder in 1974. The disease is more common in women than in men and usually appears in middle age.

Clinical Presentation

The main symptom of REM is the appearance of red patches on the skin, usually on the chest and back. These patches form a net-like pattern, which is where the disease gets its name. The patches may be slightly raised and can be itchy or painful. In some cases, the patches may also appear on the face, neck, and arms.

Pathogenesis

The exact cause of REM is unknown. However, it is believed to be related to an abnormal immune response. The disease is characterized by the accumulation of mucin in the skin. Mucin is a gel-like substance that is produced by the body's connective tissues. In REM, the body produces too much mucin, which leads to the formation of the characteristic patches.

Diagnosis

Diagnosis of REM is based on the clinical presentation and a skin biopsy. The biopsy will show an accumulation of mucin in the skin. Other tests may be done to rule out other skin diseases that can cause similar symptoms.

Treatment

Treatment for REM is aimed at reducing the symptoms and preventing the disease from progressing. This may include topical corticosteroids, antimalarial drugs, and phototherapy. In severe cases, systemic corticosteroids may be used.

Prognosis

The prognosis for REM is generally good. The disease is not life-threatening, but it can cause significant discomfort and cosmetic concerns. With treatment, the symptoms can be managed and the disease progression can be slowed.

See Also

• List of skin diseases
• Mucinosis