16-Hydroxyestradiol
16-Hydroxyestradiol (also known as 16α-Hydroxyestradiol) is a metabolite of estradiol, an important female sex hormone. It is formed in the body by the action of the enzyme cytochrome P450 on estradiol.
Structure and Properties
16-Hydroxyestradiol is a steroid hormone, like all estrogens. It has a molecular weight of 302.4 g/mol and a molecular formula of C18H24O3. Its structure includes a hydroxyl group (-OH) at the 16α position on the estradiol molecule, hence its name.
Biological Role
16-Hydroxyestradiol is one of several metabolites of estradiol that have biological activity. It binds to the estrogen receptor, a protein found in many tissues of the body, including the breast, uterus, and brain. By binding to this receptor, 16-Hydroxyestradiol can influence the growth and development of these tissues.
Health Implications
Research has suggested that 16-Hydroxyestradiol may have a role in the development of certain diseases. For example, it has been implicated in the development of breast cancer and endometriosis. However, more research is needed to fully understand these potential links.
See Also
References
<references />
Ad. Transform your life with W8MD's
GLP-1 weight loss injections special from $29.99 with insurance
|
WikiMD Medical Encyclopedia |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
