Steatocystoma multiplex: Difference between revisions
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{{Infobox medical condition | |||
| name = Steatocystoma multiplex | |||
| image = [[File:SkinTumors-P6260388.JPG|left|thumb|Steatocystoma multiplex on the skin]] | |||
| caption = Steatocystoma multiplex lesions on the skin | |||
| synonyms = | |||
| pronounce = | |||
| specialty = [[Dermatology]] | |||
| symptoms = Multiple [[sebaceous cyst]]s, usually on the trunk, upper arms, and chest | |||
| complications = Infection, scarring | |||
| onset = Adolescence or early adulthood | |||
| duration = Long-term | |||
| causes = Genetic mutation in the [[KRT17]] gene | |||
| risks = Family history | |||
| diagnosis = Clinical examination, [[histopathology]] | |||
| differential = [[Epidermoid cyst]], [[pilar cyst]], [[lipoma]] | |||
| prevention = None | |||
| treatment = Surgical removal, [[laser therapy]] | |||
| medication = | |||
| prognosis = Generally good, but lesions may recur | |||
| frequency = Rare | |||
}} | |||
[[File:Relative_incidence_of_cutaneous_cysts.jpg|Relative incidence of cutaneous cysts|thumb|left]] | |||
'''Steatocystoma Multiplex''' is a rare, benign skin condition characterized by the presence of multiple cysts known as steatocystomas. These cysts are filled with sebum, a type of oil secreted by the sebaceous glands in the skin. The condition is usually inherited in an autosomal dominant manner, meaning that an affected person has a 50% chance of passing the disorder on to each of their children. | '''Steatocystoma Multiplex''' is a rare, benign skin condition characterized by the presence of multiple cysts known as steatocystomas. These cysts are filled with sebum, a type of oil secreted by the sebaceous glands in the skin. The condition is usually inherited in an autosomal dominant manner, meaning that an affected person has a 50% chance of passing the disorder on to each of their children. | ||
== Symptoms == | == Symptoms == | ||
The primary symptom of Steatocystoma Multiplex is the presence of multiple, small, skin-colored or yellowish cysts. These cysts are typically 2-20 millimeters in diameter and are most commonly found on the chest, upper arms, and thighs. They may also occur on the scalp, face, and neck. The cysts are usually painless, but they can become inflamed and cause discomfort. | The primary symptom of Steatocystoma Multiplex is the presence of multiple, small, skin-colored or yellowish cysts. These cysts are typically 2-20 millimeters in diameter and are most commonly found on the chest, upper arms, and thighs. They may also occur on the scalp, face, and neck. The cysts are usually painless, but they can become inflamed and cause discomfort. | ||
== Causes == | == Causes == | ||
Steatocystoma Multiplex is caused by mutations in the KRT17 gene, which provides instructions for making a protein that is a component of keratin, a tough, fibrous protein that forms the structural framework of certain cells, particularly cells in the skin, hair, and nails. This mutation leads to the abnormal development of the sebaceous glands, resulting in the formation of steatocystomas. | Steatocystoma Multiplex is caused by mutations in the KRT17 gene, which provides instructions for making a protein that is a component of keratin, a tough, fibrous protein that forms the structural framework of certain cells, particularly cells in the skin, hair, and nails. This mutation leads to the abnormal development of the sebaceous glands, resulting in the formation of steatocystomas. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of Steatocystoma Multiplex is typically based on the characteristic clinical features. A skin biopsy may be performed to confirm the diagnosis. Genetic testing may also be done to identify mutations in the KRT17 gene. | The diagnosis of Steatocystoma Multiplex is typically based on the characteristic clinical features. A skin biopsy may be performed to confirm the diagnosis. Genetic testing may also be done to identify mutations in the KRT17 gene. | ||
== Treatment == | == Treatment == | ||
There is no cure for Steatocystoma Multiplex, but treatments are available to manage the symptoms. These may include surgical removal of the cysts, laser therapy, or oral medications such as isotretinoin. | There is no cure for Steatocystoma Multiplex, but treatments are available to manage the symptoms. These may include surgical removal of the cysts, laser therapy, or oral medications such as isotretinoin. | ||
== See also == | == See also == | ||
* [[Sebaceous gland]] | * [[Sebaceous gland]] | ||
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* [[Skin biopsy]] | * [[Skin biopsy]] | ||
* [[Isotretinoin]] | * [[Isotretinoin]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 14:30, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Steatocystoma multiplex | |
|---|---|
 | |
| Synonyms | |
| Pronounce | |
| Specialty | Dermatology |
| Symptoms | Multiple sebaceous cysts, usually on the trunk, upper arms, and chest |
| Complications | Infection, scarring |
| Onset | Adolescence or early adulthood |
| Duration | Long-term |
| Types | N/A |
| Causes | Genetic mutation in the KRT17 gene |
| Risks | Family history |
| Diagnosis | Clinical examination, histopathology |
| Differential diagnosis | Epidermoid cyst, pilar cyst, lipoma |
| Prevention | None |
| Treatment | Surgical removal, laser therapy |
| Medication | |
| Prognosis | Generally good, but lesions may recur |
| Frequency | Rare |
| Deaths | N/A |
Steatocystoma Multiplex is a rare, benign skin condition characterized by the presence of multiple cysts known as steatocystomas. These cysts are filled with sebum, a type of oil secreted by the sebaceous glands in the skin. The condition is usually inherited in an autosomal dominant manner, meaning that an affected person has a 50% chance of passing the disorder on to each of their children.
Symptoms[edit]
The primary symptom of Steatocystoma Multiplex is the presence of multiple, small, skin-colored or yellowish cysts. These cysts are typically 2-20 millimeters in diameter and are most commonly found on the chest, upper arms, and thighs. They may also occur on the scalp, face, and neck. The cysts are usually painless, but they can become inflamed and cause discomfort.
Causes[edit]
Steatocystoma Multiplex is caused by mutations in the KRT17 gene, which provides instructions for making a protein that is a component of keratin, a tough, fibrous protein that forms the structural framework of certain cells, particularly cells in the skin, hair, and nails. This mutation leads to the abnormal development of the sebaceous glands, resulting in the formation of steatocystomas.
Diagnosis[edit]
The diagnosis of Steatocystoma Multiplex is typically based on the characteristic clinical features. A skin biopsy may be performed to confirm the diagnosis. Genetic testing may also be done to identify mutations in the KRT17 gene.
Treatment[edit]
There is no cure for Steatocystoma Multiplex, but treatments are available to manage the symptoms. These may include surgical removal of the cysts, laser therapy, or oral medications such as isotretinoin.
