Lipschütz ulcer

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Obesity, Sleep & Internal medicine
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Lipschütz ulcer
Lipschütz ulcer
Synonyms	Ulcus vulvae acutum, acute genital ulceration
Pronounce	N/A
Specialty	N/A
Symptoms	Painful genital ulcers, fever, lymphadenopathy
Complications	Secondary infection, scarring
Onset	Sudden
Duration	Typically 2–6 weeks
Types	N/A
Causes	Often unknown, sometimes associated with Epstein-Barr virus
Risks	Immunosuppression, recent viral infection
Diagnosis	Clinical examination, exclusion of other causes
Differential diagnosis	Herpes simplex, syphilis, Behçet's disease
Prevention	N/A
Treatment	Symptomatic relief, analgesics, topical anesthetics
Medication	N/A
Prognosis	Generally good, resolves without scarring
Frequency	Rare
Deaths	N/A

Lipschütz ulcer, also known as acute genital ulceration, is a rare and non-sexually transmitted condition characterized by the sudden appearance of painful ulcers on the vulva. It was first described by Benjamin Lipschütz in 1913.

Clinical Presentation

Lipschütz ulcers typically present as one or more painful, necrotic ulcers on the vulva. These ulcers are often accompanied by systemic symptoms such as fever, malaise, and lymphadenopathy. The ulcers are usually well-circumscribed with a necrotic base and an inflammatory halo.

Etiology

The exact cause of Lipschütz ulcers is not well understood. However, they are often associated with viral infections, particularly Epstein-Barr virus (EBV) and cytomegalovirus (CMV). Other potential triggers include bacterial infections and stress.

Diagnosis

Diagnosis of Lipschütz ulcer is primarily clinical, based on the characteristic appearance of the ulcers and the exclusion of other causes of genital ulcers, such as herpes simplex virus (HSV) infection and syphilis. Laboratory tests may include viral cultures, serology, and polymerase chain reaction (PCR) testing to rule out other infections.

Treatment

Treatment of Lipschütz ulcers is mainly supportive. Pain management is crucial and may involve the use of analgesics and topical anesthetics. In some cases, corticosteroids may be prescribed to reduce inflammation. The ulcers typically resolve spontaneously within a few weeks.

Prognosis

The prognosis for Lipschütz ulcers is generally good, with most cases resolving without long-term complications. Recurrence is uncommon.

See also

• Ulcer (dermatology)
• Vulva
• Epstein-Barr virus
• Cytomegalovirus
• Herpes simplex virus