Lipedema: Difference between revisions
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{{Infobox medical condition | |||
[[File:Lipedema,_type_III.jpg| | | name = Lipedema | ||
| image = [[File:Lipedema,_type_III.jpg|250px]] | |||
| caption = Lipedema, type III | |||
| synonyms = Lipoedema, lipödem | |||
| pronounce = | |||
| specialty = [[Vascular medicine]], [[Dermatology]] | |||
| symptoms = Symmetrical swelling of the legs, pain, easy bruising | |||
| complications = [[Lymphedema]], [[Obesity]], [[Joint pain]] | |||
| onset = Usually around [[puberty]] or other times of hormonal change | |||
| duration = Long-term | |||
| causes = Unknown, possibly [[genetic]] | |||
| risks = [[Family history]], [[female]] sex | |||
| diagnosis = Based on [[physical examination]] and [[medical history]] | |||
| differential = [[Lymphedema]], [[Obesity]], [[Chronic venous insufficiency]] | |||
| prevention = None known | |||
| treatment = [[Compression therapy]], [[Liposuction]], [[Manual lymphatic drainage]] | |||
| medication = [[Pain management]] | |||
| prognosis = Variable, often progressive | |||
| frequency = Estimated to affect 11% of women | |||
}} | |||
'''Lipedema''' is a chronic disorder of adipose tissue that occurs almost exclusively in women, characterized by a symmetrical and disproportionate accumulation of subcutaneous fat, primarily in the lower body. This condition is often misdiagnosed as simple obesity or lymphedema, but it has distinct clinical features and requires specific management. | '''Lipedema''' is a chronic disorder of adipose tissue that occurs almost exclusively in women, characterized by a symmetrical and disproportionate accumulation of subcutaneous fat, primarily in the lower body. This condition is often misdiagnosed as simple obesity or lymphedema, but it has distinct clinical features and requires specific management. | ||
== Clinical Features == | == Clinical Features == | ||
Lipedema is marked by the following characteristics: | Lipedema is marked by the following characteristics: | ||
* '''Symmetrical Fat Distribution''': The fat accumulation in lipedema is typically symmetrical, affecting both legs equally from the hips to the ankles. The feet are usually spared, which helps differentiate it from [[lymphedema]]. | * '''Symmetrical Fat Distribution''': The fat accumulation in lipedema is typically symmetrical, affecting both legs equally from the hips to the ankles. The feet are usually spared, which helps differentiate it from [[lymphedema]]. | ||
* '''Pain and Tenderness''': Patients often report pain, tenderness, and easy bruising in the affected areas. The skin may feel soft and doughy. | * '''Pain and Tenderness''': Patients often report pain, tenderness, and easy bruising in the affected areas. The skin may feel soft and doughy. | ||
* '''Progressive Nature''': Lipedema tends to worsen over time, with fat deposits becoming more pronounced and potentially leading to mobility issues. | * '''Progressive Nature''': Lipedema tends to worsen over time, with fat deposits becoming more pronounced and potentially leading to mobility issues. | ||
* '''Hormonal Influence''': The condition often appears or worsens during periods of hormonal change, such as puberty, pregnancy, or menopause. | * '''Hormonal Influence''': The condition often appears or worsens during periods of hormonal change, such as puberty, pregnancy, or menopause. | ||
== Pathophysiology == | == Pathophysiology == | ||
The exact cause of lipedema is not well understood, but it is believed to involve a combination of genetic, hormonal, and inflammatory factors. The condition is thought to result from an abnormal response of adipose tissue to hormonal signals, leading to excessive fat deposition and changes in the microcirculation. | The exact cause of lipedema is not well understood, but it is believed to involve a combination of genetic, hormonal, and inflammatory factors. The condition is thought to result from an abnormal response of adipose tissue to hormonal signals, leading to excessive fat deposition and changes in the microcirculation. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of lipedema is primarily clinical, based on the characteristic distribution of fat and the presence of pain and tenderness. Imaging studies, such as [[ultrasound]] or [[MRI]], may be used to assess the extent of fat deposition and rule out other conditions. | Diagnosis of lipedema is primarily clinical, based on the characteristic distribution of fat and the presence of pain and tenderness. Imaging studies, such as [[ultrasound]] or [[MRI]], may be used to assess the extent of fat deposition and rule out other conditions. | ||
== Management == | == Management == | ||
Management of lipedema focuses on symptom relief and improving quality of life. Treatment options include: | Management of lipedema focuses on symptom relief and improving quality of life. Treatment options include: | ||
* '''Compression Therapy''': Wearing compression garments can help reduce swelling and improve circulation. | * '''Compression Therapy''': Wearing compression garments can help reduce swelling and improve circulation. | ||
* '''Manual Lymphatic Drainage''': This specialized massage technique can help reduce fluid retention and improve lymphatic flow. | * '''Manual Lymphatic Drainage''': This specialized massage technique can help reduce fluid retention and improve lymphatic flow. | ||
* '''Liposuction''': In some cases, liposuction may be considered to remove excess fat and improve mobility. | * '''Liposuction''': In some cases, liposuction may be considered to remove excess fat and improve mobility. | ||
* '''Exercise and Diet''': While diet and exercise alone cannot cure lipedema, they can help manage symptoms and prevent further weight gain. | * '''Exercise and Diet''': While diet and exercise alone cannot cure lipedema, they can help manage symptoms and prevent further weight gain. | ||
== See also == | |||
== | |||
* [[Lymphedema]] | * [[Lymphedema]] | ||
* [[Obesity]] | * [[Obesity]] | ||
* [[Adipose tissue]] | * [[Adipose tissue]] | ||
* [[Hormonal imbalance]] | * [[Hormonal imbalance]] | ||
[[Category:Adipose tissue disorders]] | [[Category:Adipose tissue disorders]] | ||
Latest revision as of 03:47, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Lipedema | |
|---|---|
| Synonyms | Lipoedema, lipödem |
| Pronounce | |
| Specialty | Vascular medicine, Dermatology |
| Symptoms | Symmetrical swelling of the legs, pain, easy bruising |
| Complications | Lymphedema, Obesity, Joint pain |
| Onset | Usually around puberty or other times of hormonal change |
| Duration | Long-term |
| Types | N/A |
| Causes | Unknown, possibly genetic |
| Risks | Family history, female sex |
| Diagnosis | Based on physical examination and medical history |
| Differential diagnosis | Lymphedema, Obesity, Chronic venous insufficiency |
| Prevention | None known |
| Treatment | Compression therapy, Liposuction, Manual lymphatic drainage |
| Medication | Pain management |
| Prognosis | Variable, often progressive |
| Frequency | Estimated to affect 11% of women |
| Deaths | N/A |
Lipedema is a chronic disorder of adipose tissue that occurs almost exclusively in women, characterized by a symmetrical and disproportionate accumulation of subcutaneous fat, primarily in the lower body. This condition is often misdiagnosed as simple obesity or lymphedema, but it has distinct clinical features and requires specific management.
Clinical Features[edit]
Lipedema is marked by the following characteristics:
- Symmetrical Fat Distribution: The fat accumulation in lipedema is typically symmetrical, affecting both legs equally from the hips to the ankles. The feet are usually spared, which helps differentiate it from lymphedema.
- Pain and Tenderness: Patients often report pain, tenderness, and easy bruising in the affected areas. The skin may feel soft and doughy.
- Progressive Nature: Lipedema tends to worsen over time, with fat deposits becoming more pronounced and potentially leading to mobility issues.
- Hormonal Influence: The condition often appears or worsens during periods of hormonal change, such as puberty, pregnancy, or menopause.
Pathophysiology[edit]
The exact cause of lipedema is not well understood, but it is believed to involve a combination of genetic, hormonal, and inflammatory factors. The condition is thought to result from an abnormal response of adipose tissue to hormonal signals, leading to excessive fat deposition and changes in the microcirculation.
Diagnosis[edit]
Diagnosis of lipedema is primarily clinical, based on the characteristic distribution of fat and the presence of pain and tenderness. Imaging studies, such as ultrasound or MRI, may be used to assess the extent of fat deposition and rule out other conditions.
Management[edit]
Management of lipedema focuses on symptom relief and improving quality of life. Treatment options include:
- Compression Therapy: Wearing compression garments can help reduce swelling and improve circulation.
- Manual Lymphatic Drainage: This specialized massage technique can help reduce fluid retention and improve lymphatic flow.
- Liposuction: In some cases, liposuction may be considered to remove excess fat and improve mobility.
- Exercise and Diet: While diet and exercise alone cannot cure lipedema, they can help manage symptoms and prevent further weight gain.