Löfgren syndrome: Difference between revisions
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{{Infobox medical condition | |||
[[File:Sarcoidosis_signs_and_symptoms.jpg| | | name = Löfgren syndrome | ||
| image = [[File:Sarcoidosis_signs_and_symptoms.jpg|250px]] | |||
| caption = Signs and symptoms of sarcoidosis, including those seen in Löfgren syndrome | |||
| field = [[Rheumatology]] | |||
| symptoms = [[Erythema nodosum]], [[arthritis]], [[hilar lymphadenopathy]] | |||
| onset = Acute | |||
| duration = Variable | |||
| causes = Unknown, associated with [[sarcoidosis]] | |||
| risks = Genetic predisposition, [[Scandinavian]] descent | |||
| diagnosis = Clinical presentation, [[chest X-ray]], [[CT scan]], [[blood test]] | |||
| differential = [[Rheumatoid arthritis]], [[tuberculosis]], [[lymphoma]] | |||
| treatment = [[Nonsteroidal anti-inflammatory drug|NSAIDs]], [[corticosteroids]] | |||
| prognosis = Generally good, often resolves spontaneously | |||
| frequency = More common in [[Northern Europe]] | |||
}} | |||
'''Löfgren syndrome''' is a clinical presentation of [[sarcoidosis]], characterized by a triad of symptoms: [[erythema nodosum]], [[bilateral hilar lymphadenopathy]], and [[arthritis]]. It is considered an acute form of sarcoidosis and is more common in certain populations, such as those of Scandinavian descent. | '''Löfgren syndrome''' is a clinical presentation of [[sarcoidosis]], characterized by a triad of symptoms: [[erythema nodosum]], [[bilateral hilar lymphadenopathy]], and [[arthritis]]. It is considered an acute form of sarcoidosis and is more common in certain populations, such as those of Scandinavian descent. | ||
== Clinical Features == | == Clinical Features == | ||
Löfgren syndrome typically presents with the following features: | Löfgren syndrome typically presents with the following features: | ||
=== Erythema Nodosum === | === Erythema Nodosum === | ||
Erythema nodosum is an inflammatory condition characterized by tender red nodules, usually located on the shins. It is a common manifestation in Löfgren syndrome and is often one of the first symptoms to appear. | Erythema nodosum is an inflammatory condition characterized by tender red nodules, usually located on the shins. It is a common manifestation in Löfgren syndrome and is often one of the first symptoms to appear. | ||
=== Bilateral Hilar Lymphadenopathy === | === Bilateral Hilar Lymphadenopathy === | ||
Bilateral hilar lymphadenopathy refers to the enlargement of the lymph nodes located at the hilum of the lungs. This is a hallmark feature of Löfgren syndrome and can be detected through a [[chest X-ray]]. | Bilateral hilar lymphadenopathy refers to the enlargement of the lymph nodes located at the hilum of the lungs. This is a hallmark feature of Löfgren syndrome and can be detected through a [[chest X-ray]]. | ||
=== Arthritis === | === Arthritis === | ||
Arthritis in Löfgren syndrome typically affects the ankles, but it can also involve other joints. The arthritis is usually acute and self-limiting, resolving within a few weeks to months. | Arthritis in Löfgren syndrome typically affects the ankles, but it can also involve other joints. The arthritis is usually acute and self-limiting, resolving within a few weeks to months. | ||
== Diagnosis == | == Diagnosis == | ||
The diagnosis of Löfgren syndrome is primarily clinical, based on the presence of the characteristic triad of symptoms. Additional tests, such as a chest X-ray or [[CT scan]], may be used to confirm bilateral hilar lymphadenopathy. A [[biopsy]] is generally not required unless the diagnosis is uncertain. | The diagnosis of Löfgren syndrome is primarily clinical, based on the presence of the characteristic triad of symptoms. Additional tests, such as a chest X-ray or [[CT scan]], may be used to confirm bilateral hilar lymphadenopathy. A [[biopsy]] is generally not required unless the diagnosis is uncertain. | ||
== Prognosis == | == Prognosis == | ||
Löfgren syndrome generally has a good prognosis, with most patients experiencing spontaneous resolution of symptoms within 6 months to 2 years. The presence of erythema nodosum is associated with a favorable outcome. | Löfgren syndrome generally has a good prognosis, with most patients experiencing spontaneous resolution of symptoms within 6 months to 2 years. The presence of erythema nodosum is associated with a favorable outcome. | ||
== Treatment == | == Treatment == | ||
Treatment for Löfgren syndrome is often supportive, focusing on symptom relief. Nonsteroidal anti-inflammatory drugs ([[NSAIDs]]) are commonly used to manage pain and inflammation. In more severe cases, [[corticosteroids]] may be prescribed. | Treatment for Löfgren syndrome is often supportive, focusing on symptom relief. Nonsteroidal anti-inflammatory drugs ([[NSAIDs]]) are commonly used to manage pain and inflammation. In more severe cases, [[corticosteroids]] may be prescribed. | ||
== See also == | |||
== | |||
* [[Sarcoidosis]] | * [[Sarcoidosis]] | ||
* [[Erythema nodosum]] | * [[Erythema nodosum]] | ||
* [[Arthritis]] | * [[Arthritis]] | ||
* [[Lymphadenopathy]] | * [[Lymphadenopathy]] | ||
{{Sarcoidosis}} | {{Sarcoidosis}} | ||
[[Category:Sarcoidosis]] | [[Category:Sarcoidosis]] | ||
[[Category:Rheumatology]] | [[Category:Rheumatology]] | ||
[[Category:Pulmonology]] | [[Category:Pulmonology]] | ||
Latest revision as of 03:45, 8 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Löfgren syndrome | |
|---|---|
| |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Erythema nodosum, arthritis, hilar lymphadenopathy |
| Complications | N/A |
| Onset | Acute |
| Duration | Variable |
| Types | N/A |
| Causes | Unknown, associated with sarcoidosis |
| Risks | Genetic predisposition, Scandinavian descent |
| Diagnosis | Clinical presentation, chest X-ray, CT scan, blood test |
| Differential diagnosis | Rheumatoid arthritis, tuberculosis, lymphoma |
| Prevention | N/A |
| Treatment | NSAIDs, corticosteroids |
| Medication | N/A |
| Prognosis | Generally good, often resolves spontaneously |
| Frequency | More common in Northern Europe |
| Deaths | N/A |
Löfgren syndrome is a clinical presentation of sarcoidosis, characterized by a triad of symptoms: erythema nodosum, bilateral hilar lymphadenopathy, and arthritis. It is considered an acute form of sarcoidosis and is more common in certain populations, such as those of Scandinavian descent.
Clinical Features[edit]
Löfgren syndrome typically presents with the following features:
Erythema Nodosum[edit]
Erythema nodosum is an inflammatory condition characterized by tender red nodules, usually located on the shins. It is a common manifestation in Löfgren syndrome and is often one of the first symptoms to appear.
Bilateral Hilar Lymphadenopathy[edit]
Bilateral hilar lymphadenopathy refers to the enlargement of the lymph nodes located at the hilum of the lungs. This is a hallmark feature of Löfgren syndrome and can be detected through a chest X-ray.
Arthritis[edit]
Arthritis in Löfgren syndrome typically affects the ankles, but it can also involve other joints. The arthritis is usually acute and self-limiting, resolving within a few weeks to months.
Diagnosis[edit]
The diagnosis of Löfgren syndrome is primarily clinical, based on the presence of the characteristic triad of symptoms. Additional tests, such as a chest X-ray or CT scan, may be used to confirm bilateral hilar lymphadenopathy. A biopsy is generally not required unless the diagnosis is uncertain.
Prognosis[edit]
Löfgren syndrome generally has a good prognosis, with most patients experiencing spontaneous resolution of symptoms within 6 months to 2 years. The presence of erythema nodosum is associated with a favorable outcome.
Treatment[edit]
Treatment for Löfgren syndrome is often supportive, focusing on symptom relief. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to manage pain and inflammation. In more severe cases, corticosteroids may be prescribed.
See also[edit]
| Sarcoidosis |
|---|
|
|
