Synovial sarcoma: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Synovial sarcoma
| image          = [[File:Monophasic_synovial_sarcoma_-_high_mag.jpg|alt=High magnification micrograph of a monophasic synovial sarcoma]]
| caption        = High magnification micrograph of a monophasic synovial sarcoma
| field          = [[Oncology]]
| synonyms        = Malignant synovioma
| symptoms        = [[Swelling]], [[pain]], [[limited range of motion]]
| complications  = [[Metastasis]], [[recurrence]]
| onset          = Typically between ages 15 and 40
| duration        = Chronic
| types          = Monophasic, biphasic, poorly differentiated
| causes          = [[Genetic mutation]]
| risks          = [[Genetic predisposition]], [[radiation exposure]]
| diagnosis      = [[Biopsy]], [[imaging studies]]
| differential    = [[Fibrosarcoma]], [[malignant peripheral nerve sheath tumor]], [[leiomyosarcoma]]
| prevention      = None known
| treatment      = [[Surgery]], [[radiation therapy]], [[chemotherapy]]
| medication      = [[Doxorubicin]], [[ifosfamide]]
| prognosis      = Variable, depends on stage and response to treatment
| frequency      = Rare, approximately 1-3 per million per year
| deaths          = Varies, dependent on stage and treatment
}}
'''Synovial sarcoma''' is a rare form of [[cancer]] that typically arises near the joints of the arm, neck, or leg, but can occur in any part of the body. It is named for its resemblance to [[synovium]], the tissue that lines the joints, although it does not actually arise from this tissue.  
'''Synovial sarcoma''' is a rare form of [[cancer]] that typically arises near the joints of the arm, neck, or leg, but can occur in any part of the body. It is named for its resemblance to [[synovium]], the tissue that lines the joints, although it does not actually arise from this tissue.  
== Symptoms ==
== Symptoms ==
The most common symptom of synovial sarcoma is a painless swelling or mass that may be associated with [[muscle weakness]] or limitation of motion. Symptoms may be present for several years before a diagnosis is made. Other symptoms can include pain, which is a late event, or a change in size of the mass.
The most common symptom of synovial sarcoma is a painless swelling or mass that may be associated with [[muscle weakness]] or limitation of motion. Symptoms may be present for several years before a diagnosis is made. Other symptoms can include pain, which is a late event, or a change in size of the mass.
== Diagnosis ==
== Diagnosis ==
Diagnosis of synovial sarcoma begins with a thorough [[medical history]] and physical examination. Imaging tests such as [[X-ray]], [[MRI]], or [[CT scan]] may be used to identify the location and size of the tumor. A [[biopsy]] is then performed to confirm the diagnosis. The biopsy can be done through a needle inserted into the tumor or through a small incision.
Diagnosis of synovial sarcoma begins with a thorough [[medical history]] and physical examination. Imaging tests such as [[X-ray]], [[MRI]], or [[CT scan]] may be used to identify the location and size of the tumor. A [[biopsy]] is then performed to confirm the diagnosis. The biopsy can be done through a needle inserted into the tumor or through a small incision.
== Treatment ==
== Treatment ==
Treatment for synovial sarcoma typically involves a combination of [[surgery]], [[radiation therapy]], and [[chemotherapy]]. The goal of treatment is to remove the tumor and any nearby cancer cells, to relieve symptoms, and to prevent the cancer from spreading to other parts of the body.
Treatment for synovial sarcoma typically involves a combination of [[surgery]], [[radiation therapy]], and [[chemotherapy]]. The goal of treatment is to remove the tumor and any nearby cancer cells, to relieve symptoms, and to prevent the cancer from spreading to other parts of the body.
== Prognosis ==
== Prognosis ==
The prognosis for synovial sarcoma varies depending on a number of factors, including the size and location of the tumor, the stage of the cancer, and the patient's overall health. In general, the survival rate for synovial sarcoma is lower than that for other types of soft tissue sarcoma.
The prognosis for synovial sarcoma varies depending on a number of factors, including the size and location of the tumor, the stage of the cancer, and the patient's overall health. In general, the survival rate for synovial sarcoma is lower than that for other types of soft tissue sarcoma.
== See also ==
== See also ==
* [[Soft tissue sarcoma]]
* [[Soft tissue sarcoma]]
* [[Cancer]]
* [[Cancer]]
* [[Oncology]]
* [[Oncology]]
== References ==
== References ==
<references />
<references />
[[Category:Cancer]]
[[Category:Cancer]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Rare diseases]]
[[Category:Rare diseases]]
{{stub}}
{{stub}}
<gallery>
File:Monophasic_synovial_sarcoma_-_high_mag.jpg
</gallery>

Latest revision as of 22:54, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Synovial sarcoma
High magnification micrograph of a monophasic synovial sarcoma
Synonyms Malignant synovioma
Pronounce N/A
Specialty N/A
Symptoms Swelling, pain, limited range of motion
Complications Metastasis, recurrence
Onset Typically between ages 15 and 40
Duration Chronic
Types Monophasic, biphasic, poorly differentiated
Causes Genetic mutation
Risks Genetic predisposition, radiation exposure
Diagnosis Biopsy, imaging studies
Differential diagnosis Fibrosarcoma, malignant peripheral nerve sheath tumor, leiomyosarcoma
Prevention None known
Treatment Surgery, radiation therapy, chemotherapy
Medication Doxorubicin, ifosfamide
Prognosis Variable, depends on stage and response to treatment
Frequency Rare, approximately 1-3 per million per year
Deaths Varies, dependent on stage and treatment


Synovial sarcoma is a rare form of cancer that typically arises near the joints of the arm, neck, or leg, but can occur in any part of the body. It is named for its resemblance to synovium, the tissue that lines the joints, although it does not actually arise from this tissue.

Symptoms[edit]

The most common symptom of synovial sarcoma is a painless swelling or mass that may be associated with muscle weakness or limitation of motion. Symptoms may be present for several years before a diagnosis is made. Other symptoms can include pain, which is a late event, or a change in size of the mass.

Diagnosis[edit]

Diagnosis of synovial sarcoma begins with a thorough medical history and physical examination. Imaging tests such as X-ray, MRI, or CT scan may be used to identify the location and size of the tumor. A biopsy is then performed to confirm the diagnosis. The biopsy can be done through a needle inserted into the tumor or through a small incision.

Treatment[edit]

Treatment for synovial sarcoma typically involves a combination of surgery, radiation therapy, and chemotherapy. The goal of treatment is to remove the tumor and any nearby cancer cells, to relieve symptoms, and to prevent the cancer from spreading to other parts of the body.

Prognosis[edit]

The prognosis for synovial sarcoma varies depending on a number of factors, including the size and location of the tumor, the stage of the cancer, and the patient's overall health. In general, the survival rate for synovial sarcoma is lower than that for other types of soft tissue sarcoma.

See also[edit]

References[edit]

<references />

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