Retinoschisis: Difference between revisions
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{{Infobox medical condition | |||
| name = Retinoschisis | |||
| image = [[File:X-linked_recessive_(2).svg|200px]] | |||
| caption = X-linked recessive inheritance pattern | |||
| field = [[Ophthalmology]] | |||
| synonyms = | |||
| symptoms = [[Vision loss]], [[retinal detachment]] | |||
| complications = [[Blindness]], [[macular degeneration]] | |||
| onset = Childhood or adulthood | |||
| duration = Lifelong | |||
| types = [[Juvenile retinoschisis]], [[senile retinoschisis]] | |||
| causes = Genetic mutations, primarily in the [[RS1 gene]] | |||
| risks = Family history, male gender (for X-linked type) | |||
| diagnosis = [[Ophthalmoscopy]], [[optical coherence tomography]], [[electroretinography]] | |||
| differential = [[Retinal detachment]], [[macular hole]], [[vitreous hemorrhage]] | |||
| treatment = Monitoring, [[vitrectomy]] in severe cases | |||
| medication = None specific, supportive care | |||
| prognosis = Variable, can lead to significant vision loss | |||
| frequency = Rare | |||
}} | |||
'''Retinoschisis''' is a medical condition characterized by the splitting of the [[retina]], the light-sensitive tissue lining the back of the eye. This condition can lead to severe vision loss and is often diagnosed in childhood, although it can also occur later in life. | '''Retinoschisis''' is a medical condition characterized by the splitting of the [[retina]], the light-sensitive tissue lining the back of the eye. This condition can lead to severe vision loss and is often diagnosed in childhood, although it can also occur later in life. | ||
==Causes== | ==Causes== | ||
Retinoschisis is usually caused by mutations in the [[RS1]] gene. This gene provides instructions for making a protein that is essential for the structure and function of the retina. Mutations in the RS1 gene disrupt the normal organization of the retina, leading to the characteristic splitting seen in retinoschisis. | Retinoschisis is usually caused by mutations in the [[RS1]] gene. This gene provides instructions for making a protein that is essential for the structure and function of the retina. Mutations in the RS1 gene disrupt the normal organization of the retina, leading to the characteristic splitting seen in retinoschisis. | ||
==Symptoms== | ==Symptoms== | ||
The symptoms of retinoschisis can vary widely, but often include [[blurred vision]], [[difficulty with fine detail vision]] (such as reading or recognizing faces), and [[peripheral vision loss]]. In severe cases, retinoschisis can lead to [[retinal detachment]], a serious condition that can cause permanent vision loss. | The symptoms of retinoschisis can vary widely, but often include [[blurred vision]], [[difficulty with fine detail vision]] (such as reading or recognizing faces), and [[peripheral vision loss]]. In severe cases, retinoschisis can lead to [[retinal detachment]], a serious condition that can cause permanent vision loss. | ||
==Diagnosis== | ==Diagnosis== | ||
Retinoschisis is typically diagnosed through a comprehensive [[eye examination]]. This may include a [[visual acuity test]], a [[dilated eye exam]], and [[optical coherence tomography]] (OCT), a non-invasive imaging test that uses light waves to take cross-section pictures of the retina. | Retinoschisis is typically diagnosed through a comprehensive [[eye examination]]. This may include a [[visual acuity test]], a [[dilated eye exam]], and [[optical coherence tomography]] (OCT), a non-invasive imaging test that uses light waves to take cross-section pictures of the retina. | ||
==Treatment== | ==Treatment== | ||
There is currently no cure for retinoschisis, but treatment can help manage symptoms and prevent complications. Treatment options may include [[eye glasses]] or [[contact lenses]] to correct vision problems, and regular monitoring to detect and treat complications such as retinal detachment. | There is currently no cure for retinoschisis, but treatment can help manage symptoms and prevent complications. Treatment options may include [[eye glasses]] or [[contact lenses]] to correct vision problems, and regular monitoring to detect and treat complications such as retinal detachment. | ||
==See also== | ==See also== | ||
* [[Retina]] | * [[Retina]] | ||
* [[Retinal detachment]] | * [[Retinal detachment]] | ||
* [[RS1 gene]] | * [[RS1 gene]] | ||
[[Category:Eye diseases]] | [[Category:Eye diseases]] | ||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
{{Eye-disease-stub}} | {{Eye-disease-stub}} | ||
Latest revision as of 22:34, 6 April 2025
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Obesity, Sleep & Internal medicine
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| Retinoschisis | |
|---|---|
.svg)
| |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Vision loss, retinal detachment |
| Complications | Blindness, macular degeneration |
| Onset | Childhood or adulthood |
| Duration | Lifelong |
| Types | Juvenile retinoschisis, senile retinoschisis |
| Causes | Genetic mutations, primarily in the RS1 gene |
| Risks | Family history, male gender (for X-linked type) |
| Diagnosis | Ophthalmoscopy, optical coherence tomography, electroretinography |
| Differential diagnosis | Retinal detachment, macular hole, vitreous hemorrhage |
| Prevention | N/A |
| Treatment | Monitoring, vitrectomy in severe cases |
| Medication | None specific, supportive care |
| Prognosis | Variable, can lead to significant vision loss |
| Frequency | Rare |
| Deaths | N/A |
Retinoschisis is a medical condition characterized by the splitting of the retina, the light-sensitive tissue lining the back of the eye. This condition can lead to severe vision loss and is often diagnosed in childhood, although it can also occur later in life.
Causes[edit]
Retinoschisis is usually caused by mutations in the RS1 gene. This gene provides instructions for making a protein that is essential for the structure and function of the retina. Mutations in the RS1 gene disrupt the normal organization of the retina, leading to the characteristic splitting seen in retinoschisis.
Symptoms[edit]
The symptoms of retinoschisis can vary widely, but often include blurred vision, difficulty with fine detail vision (such as reading or recognizing faces), and peripheral vision loss. In severe cases, retinoschisis can lead to retinal detachment, a serious condition that can cause permanent vision loss.
Diagnosis[edit]
Retinoschisis is typically diagnosed through a comprehensive eye examination. This may include a visual acuity test, a dilated eye exam, and optical coherence tomography (OCT), a non-invasive imaging test that uses light waves to take cross-section pictures of the retina.
Treatment[edit]
There is currently no cure for retinoschisis, but treatment can help manage symptoms and prevent complications. Treatment options may include eye glasses or contact lenses to correct vision problems, and regular monitoring to detect and treat complications such as retinal detachment.
See also[edit]
