Löffler's syndrome: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Löffler's syndrome
| image          = [[File:Blausen_0352_Eosinophil_(crop).png|left|thumb|Eosinophil, a type of white blood cell involved in Löffler's syndrome]]
| caption        = Eosinophil, a type of white blood cell involved in Löffler's syndrome
| field          = [[Pulmonology]]
| synonyms        = Eosinophilic pneumonia
| symptoms        = [[Cough]], [[fever]], [[dyspnea]] (shortness of breath)
| complications  = [[Respiratory failure]]
| onset          = Acute
| duration        = Usually self-limiting
| causes          = [[Parasitic infection]], [[drug reaction]], [[allergic reaction]]
| risks          = Exposure to parasites, certain medications
| diagnosis      = [[Chest X-ray]], [[blood test]] showing [[eosinophilia]]
| differential    = [[Asthma]], [[chronic eosinophilic pneumonia]], [[hypereosinophilic syndrome]]
| treatment      = Treat underlying cause, [[corticosteroids]]
| prognosis      = Generally good with treatment
| frequency      = Rare
}}
'''Löffler's syndrome''' is a rare, transient respiratory illness characterized by lung inflammation and blood eosinophilia. It is named after Wilhelm Löffler, a German physician who first described the condition in 1932.  
'''Löffler's syndrome''' is a rare, transient respiratory illness characterized by lung inflammation and blood eosinophilia. It is named after Wilhelm Löffler, a German physician who first described the condition in 1932.  
== Causes ==
== Causes ==
Löffler's syndrome is typically caused by a parasitic infection or an allergic reaction to certain drugs. The most common parasites associated with the condition include [[Ascaris lumbricoides]], [[Strongyloides stercoralis]], and [[Toxocara canis]]. Drugs that can cause Löffler's syndrome include [[penicillin]], [[sulfa drugs]], and [[NSAIDs]].
Löffler's syndrome is typically caused by a parasitic infection or an allergic reaction to certain drugs. The most common parasites associated with the condition include [[Ascaris lumbricoides]], [[Strongyloides stercoralis]], and [[Toxocara canis]]. Drugs that can cause Löffler's syndrome include [[penicillin]], [[sulfa drugs]], and [[NSAIDs]].
== Symptoms ==
== Symptoms ==
The symptoms of Löffler's syndrome can vary, but they often include cough, shortness of breath, and wheezing. Other symptoms may include fever, chest pain, and weight loss. In some cases, patients may also develop a rash or other skin symptoms.
The symptoms of Löffler's syndrome can vary, but they often include cough, shortness of breath, and wheezing. Other symptoms may include fever, chest pain, and weight loss. In some cases, patients may also develop a rash or other skin symptoms.
== Diagnosis ==
== Diagnosis ==
The diagnosis of Löffler's syndrome is typically based on the presence of characteristic symptoms, a history of exposure to a potential cause, and the finding of eosinophilia on a blood test. Imaging tests, such as a chest X-ray or CT scan, may also be used to help confirm the diagnosis.
The diagnosis of Löffler's syndrome is typically based on the presence of characteristic symptoms, a history of exposure to a potential cause, and the finding of eosinophilia on a blood test. Imaging tests, such as a chest X-ray or CT scan, may also be used to help confirm the diagnosis.
== Treatment ==
== Treatment ==
The treatment of Löffler's syndrome depends on the underlying cause. If the condition is caused by a parasitic infection, antiparasitic drugs will be used. If it is caused by a drug reaction, the offending drug will be discontinued. In some cases, corticosteroids may also be used to help reduce inflammation and ease symptoms.
The treatment of Löffler's syndrome depends on the underlying cause. If the condition is caused by a parasitic infection, antiparasitic drugs will be used. If it is caused by a drug reaction, the offending drug will be discontinued. In some cases, corticosteroids may also be used to help reduce inflammation and ease symptoms.
== Prognosis ==
== Prognosis ==
The prognosis for Löffler's syndrome is generally good. Most patients recover fully with appropriate treatment, although some may experience a recurrence of symptoms if they are re-exposed to the causative agent.
The prognosis for Löffler's syndrome is generally good. Most patients recover fully with appropriate treatment, although some may experience a recurrence of symptoms if they are re-exposed to the causative agent.
== See also ==
== See also ==
* [[Eosinophilia]]
* [[Eosinophilia]]
* [[Pulmonary eosinophilia]]
* [[Pulmonary eosinophilia]]
* [[Hypereosinophilic syndrome]]
* [[Hypereosinophilic syndrome]]
[[Category:Respiratory diseases]]
[[Category:Respiratory diseases]]
[[Category:Rare diseases]]
[[Category:Rare diseases]]
[[Category:Syndromes]]
[[Category:Syndromes]]
{{stub}}
{{stub}}
== Löffler's syndrome ==
<gallery>
File:Blausen_0352_Eosinophil_(crop).png
</gallery>

Latest revision as of 21:40, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Löffler's syndrome
Eosinophil, a type of white blood cell involved in Löffler's syndrome
Synonyms Eosinophilic pneumonia
Pronounce N/A
Specialty N/A
Symptoms Cough, fever, dyspnea (shortness of breath)
Complications Respiratory failure
Onset Acute
Duration Usually self-limiting
Types N/A
Causes Parasitic infection, drug reaction, allergic reaction
Risks Exposure to parasites, certain medications
Diagnosis Chest X-ray, blood test showing eosinophilia
Differential diagnosis Asthma, chronic eosinophilic pneumonia, hypereosinophilic syndrome
Prevention N/A
Treatment Treat underlying cause, corticosteroids
Medication N/A
Prognosis Generally good with treatment
Frequency Rare
Deaths N/A


Löffler's syndrome is a rare, transient respiratory illness characterized by lung inflammation and blood eosinophilia. It is named after Wilhelm Löffler, a German physician who first described the condition in 1932.

Causes[edit]

Löffler's syndrome is typically caused by a parasitic infection or an allergic reaction to certain drugs. The most common parasites associated with the condition include Ascaris lumbricoides, Strongyloides stercoralis, and Toxocara canis. Drugs that can cause Löffler's syndrome include penicillin, sulfa drugs, and NSAIDs.

Symptoms[edit]

The symptoms of Löffler's syndrome can vary, but they often include cough, shortness of breath, and wheezing. Other symptoms may include fever, chest pain, and weight loss. In some cases, patients may also develop a rash or other skin symptoms.

Diagnosis[edit]

The diagnosis of Löffler's syndrome is typically based on the presence of characteristic symptoms, a history of exposure to a potential cause, and the finding of eosinophilia on a blood test. Imaging tests, such as a chest X-ray or CT scan, may also be used to help confirm the diagnosis.

Treatment[edit]

The treatment of Löffler's syndrome depends on the underlying cause. If the condition is caused by a parasitic infection, antiparasitic drugs will be used. If it is caused by a drug reaction, the offending drug will be discontinued. In some cases, corticosteroids may also be used to help reduce inflammation and ease symptoms.

Prognosis[edit]

The prognosis for Löffler's syndrome is generally good. Most patients recover fully with appropriate treatment, although some may experience a recurrence of symptoms if they are re-exposed to the causative agent.

See also[edit]

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