Fibrosarcoma: Difference between revisions
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{{Infobox medical condition | |||
| name = Fibrosarcoma | |||
| image = [[File:Malignant_peripheral_nerve_sheath_tumour_-_high_mag.jpg|left|thumb|Fibrosarcoma under a microscope]] | |||
| caption = Histopathological image of fibrosarcoma | |||
| field = [[Oncology]] | |||
| synonyms = | |||
| symptoms = [[Swelling]], [[pain]], [[lump]] | |||
| complications = [[Metastasis]], [[recurrence]] | |||
| onset = Typically in [[adults]] | |||
| duration = | |||
| types = | |||
| causes = | |||
| risks = [[Genetic predisposition]], [[radiation exposure]] | |||
| diagnosis = [[Biopsy]], [[imaging studies]] | |||
| differential = [[Liposarcoma]], [[leiomyosarcoma]], [[malignant peripheral nerve sheath tumor]] | |||
| prevention = | |||
| treatment = [[Surgery]], [[radiation therapy]], [[chemotherapy]] | |||
| medication = | |||
| prognosis = Variable, depends on stage and location | |||
| frequency = Rare | |||
}} | |||
{{short description|A type of cancer that develops from fibrous connective tissue}} | {{short description|A type of cancer that develops from fibrous connective tissue}} | ||
{{For|the condition in cats|Vaccine-associated sarcoma}} | {{For|the condition in cats|Vaccine-associated sarcoma}} | ||
== Introduction == | |||
== | [[File:Cat_after_Fibrosarcom_op.jpg|left|thumb|A cat post-surgery for fibrosarcoma]] | ||
[[File:Cat_after_Fibrosarcom_op.jpg|thumb | |||
'''Fibrosarcoma''' is a malignant [[tumor]] that arises from [[fibroblasts]], the cells responsible for producing [[collagen]] and other fibers. It is a type of [[soft tissue sarcoma]] and can occur in any part of the body, although it is most commonly found in the [[extremities]], [[trunk]], and [[head and neck]] region. | '''Fibrosarcoma''' is a malignant [[tumor]] that arises from [[fibroblasts]], the cells responsible for producing [[collagen]] and other fibers. It is a type of [[soft tissue sarcoma]] and can occur in any part of the body, although it is most commonly found in the [[extremities]], [[trunk]], and [[head and neck]] region. | ||
==Pathophysiology== | ==Pathophysiology== | ||
Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The [[histological]] appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern. | Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The [[histological]] appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the [[lungs]] and other organs. | Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the [[lungs]] and other organs. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of fibrosarcoma is typically made through a combination of [[imaging studies]] and [[biopsy]]. Imaging techniques such as [[MRI]] and [[CT scan]] are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas. | The diagnosis of fibrosarcoma is typically made through a combination of [[imaging studies]] and [[biopsy]]. Imaging techniques such as [[MRI]] and [[CT scan]] are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas. | ||
==Treatment== | ==Treatment== | ||
The primary treatment for fibrosarcoma is [[surgical resection]] with wide margins to ensure complete removal of the tumor. In some cases, [[radiation therapy]] and/or [[chemotherapy]] may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease. | The primary treatment for fibrosarcoma is [[surgical resection]] with wide margins to ensure complete removal of the tumor. In some cases, [[radiation therapy]] and/or [[chemotherapy]] may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis. | The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis. | ||
==See also== | |||
== | |||
* [[Soft tissue sarcoma]] | * [[Soft tissue sarcoma]] | ||
* [[Vaccine-associated sarcoma]] | * [[Vaccine-associated sarcoma]] | ||
* [[Oncology]] | * [[Oncology]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
[[Category:Sarcoma]] | [[Category:Sarcoma]] | ||
Latest revision as of 16:31, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Fibrosarcoma | |
|---|---|
 | |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Swelling, pain, lump |
| Complications | Metastasis, recurrence |
| Onset | Typically in adults |
| Duration | |
| Types | |
| Causes | |
| Risks | Genetic predisposition, radiation exposure |
| Diagnosis | Biopsy, imaging studies |
| Differential diagnosis | Liposarcoma, leiomyosarcoma, malignant peripheral nerve sheath tumor |
| Prevention | |
| Treatment | Surgery, radiation therapy, chemotherapy |
| Medication | |
| Prognosis | Variable, depends on stage and location |
| Frequency | Rare |
| Deaths | N/A |
A type of cancer that develops from fibrous connective tissue
Introduction[edit]
Fibrosarcoma is a malignant tumor that arises from fibroblasts, the cells responsible for producing collagen and other fibers. It is a type of soft tissue sarcoma and can occur in any part of the body, although it is most commonly found in the extremities, trunk, and head and neck region.
Pathophysiology[edit]
Fibrosarcomas are characterized by the proliferation of atypical fibroblasts and the production of excessive amounts of collagen. These tumors are typically poorly circumscribed and can invade surrounding tissues. The histological appearance of fibrosarcoma includes spindle-shaped cells arranged in a herringbone pattern.
Clinical Presentation[edit]
Patients with fibrosarcoma may present with a painless mass that gradually increases in size. As the tumor grows, it may cause pain or functional impairment depending on its location. In advanced cases, fibrosarcoma can metastasize to the lungs and other organs.
Diagnosis[edit]
The diagnosis of fibrosarcoma is typically made through a combination of imaging studies and biopsy. Imaging techniques such as MRI and CT scan are used to assess the extent of the tumor and its relationship to surrounding structures. A biopsy is necessary to confirm the diagnosis and to differentiate fibrosarcoma from other types of soft tissue sarcomas.
Treatment[edit]
The primary treatment for fibrosarcoma is surgical resection with wide margins to ensure complete removal of the tumor. In some cases, radiation therapy and/or chemotherapy may be used as adjunctive treatments to reduce the risk of recurrence or to treat metastatic disease.
Prognosis[edit]
The prognosis for patients with fibrosarcoma depends on several factors, including the size and location of the tumor, the completeness of surgical resection, and the presence of metastases. Early detection and complete surgical removal of the tumor are associated with a better prognosis.
