Elliptocyte: Difference between revisions
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{{Infobox medical condition | |||
| name = Elliptocyte | |||
| image = [[File:Elliptocytosis.jpg|left|thumb|Elliptocytes in a blood smear]] | |||
| caption = Elliptocytes observed in a blood smear | |||
| field = [[Hematology]] | |||
| symptoms = [[Anemia]], [[fatigue]], [[jaundice]] | |||
| complications = [[Splenomegaly]], [[gallstones]] | |||
| onset = Congenital | |||
| duration = Lifelong | |||
| causes = Genetic mutations in [[spectrin]], [[protein 4.1]], or [[glycophorin C]] | |||
| risks = Family history of [[hereditary elliptocytosis]] | |||
| diagnosis = [[Blood smear]], [[genetic testing]] | |||
| differential = [[Hereditary spherocytosis]], [[iron deficiency anemia]] | |||
| treatment = [[Folic acid supplementation]], [[splenectomy]] | |||
| frequency = 1 in 2,000 to 4,000 individuals | |||
}} | |||
'''Elliptocyte''' is a type of red blood cell that is elliptical rather than the typical biconcave disk shape. Elliptocytes are seen in various conditions, most notably in a condition known as [[Elliptocytosis|hereditary elliptocytosis]]. | '''Elliptocyte''' is a type of red blood cell that is elliptical rather than the typical biconcave disk shape. Elliptocytes are seen in various conditions, most notably in a condition known as [[Elliptocytosis|hereditary elliptocytosis]]. | ||
== Introduction == | |||
== | |||
Elliptocytes are oval or elliptical in shape, hence the name. They are also known as ovalocytes. These cells are typically seen in a blood smear of individuals with hereditary elliptocytosis, a genetic disorder. However, they can also be seen in other conditions such as [[Iron Deficiency Anemia|iron deficiency anemia]], [[Thalassemia|thalassemia]], and [[Myelofibrosis|myelofibrosis]]. | Elliptocytes are oval or elliptical in shape, hence the name. They are also known as ovalocytes. These cells are typically seen in a blood smear of individuals with hereditary elliptocytosis, a genetic disorder. However, they can also be seen in other conditions such as [[Iron Deficiency Anemia|iron deficiency anemia]], [[Thalassemia|thalassemia]], and [[Myelofibrosis|myelofibrosis]]. | ||
== Hereditary Elliptocytosis == | == Hereditary Elliptocytosis == | ||
[[Hereditary Elliptocytosis|Hereditary elliptocytosis]] is a blood disorder in which a large number of elliptocytes are present in the blood. This condition is caused by mutations in the genes that provide instructions for making proteins found in red blood cells. These mutations lead to abnormalities in the red blood cell membrane, causing the cells to become elliptical. | [[Hereditary Elliptocytosis|Hereditary elliptocytosis]] is a blood disorder in which a large number of elliptocytes are present in the blood. This condition is caused by mutations in the genes that provide instructions for making proteins found in red blood cells. These mutations lead to abnormalities in the red blood cell membrane, causing the cells to become elliptical. | ||
== Diagnosis == | == Diagnosis == | ||
The presence of elliptocytes can be confirmed by a [[Peripheral Blood Smear|peripheral blood smear]] test. In this test, a sample of the patient's blood is examined under a microscope. The elliptical shape of the red blood cells can be clearly seen in this test. | The presence of elliptocytes can be confirmed by a [[Peripheral Blood Smear|peripheral blood smear]] test. In this test, a sample of the patient's blood is examined under a microscope. The elliptical shape of the red blood cells can be clearly seen in this test. | ||
== Treatment == | == Treatment == | ||
The treatment for conditions that cause the presence of elliptocytes in the blood depends on the underlying condition. For example, in the case of hereditary elliptocytosis, treatment may not be necessary unless the condition is severe. In severe cases, a [[Blood Transfusion|blood transfusion]] may be required. | The treatment for conditions that cause the presence of elliptocytes in the blood depends on the underlying condition. For example, in the case of hereditary elliptocytosis, treatment may not be necessary unless the condition is severe. In severe cases, a [[Blood Transfusion|blood transfusion]] may be required. | ||
==Images== | |||
<gallery> | |||
File:Hereditary_Elliptocytosis_in_a_70-year-old_man.tif|Hereditary Elliptocytosis in a 70-year-old man | |||
File:Poikilocytes_-_Red_blood_cell_types.jpg|Poikilocytes - Red blood cell types | |||
</gallery> | |||
== See Also == | == See Also == | ||
* [[Red Blood Cell]] | * [[Red Blood Cell]] | ||
* [[Anemia]] | * [[Anemia]] | ||
* [[Blood Disorders]] | * [[Blood Disorders]] | ||
[[Category:Medical Terms]] | [[Category:Medical Terms]] | ||
[[Category:Blood Disorders]] | [[Category:Blood Disorders]] | ||
[[Category:Genetic Disorders]] | [[Category:Genetic Disorders]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 16:01, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Elliptocyte | |
|---|---|
 | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Anemia, fatigue, jaundice |
| Complications | Splenomegaly, gallstones |
| Onset | Congenital |
| Duration | Lifelong |
| Types | N/A |
| Causes | Genetic mutations in spectrin, protein 4.1, or glycophorin C |
| Risks | Family history of hereditary elliptocytosis |
| Diagnosis | Blood smear, genetic testing |
| Differential diagnosis | Hereditary spherocytosis, iron deficiency anemia |
| Prevention | N/A |
| Treatment | Folic acid supplementation, splenectomy |
| Medication | N/A |
| Prognosis | N/A |
| Frequency | 1 in 2,000 to 4,000 individuals |
| Deaths | N/A |
Elliptocyte is a type of red blood cell that is elliptical rather than the typical biconcave disk shape. Elliptocytes are seen in various conditions, most notably in a condition known as hereditary elliptocytosis.
Introduction[edit]
Elliptocytes are oval or elliptical in shape, hence the name. They are also known as ovalocytes. These cells are typically seen in a blood smear of individuals with hereditary elliptocytosis, a genetic disorder. However, they can also be seen in other conditions such as iron deficiency anemia, thalassemia, and myelofibrosis.
Hereditary Elliptocytosis[edit]
Hereditary elliptocytosis is a blood disorder in which a large number of elliptocytes are present in the blood. This condition is caused by mutations in the genes that provide instructions for making proteins found in red blood cells. These mutations lead to abnormalities in the red blood cell membrane, causing the cells to become elliptical.
Diagnosis[edit]
The presence of elliptocytes can be confirmed by a peripheral blood smear test. In this test, a sample of the patient's blood is examined under a microscope. The elliptical shape of the red blood cells can be clearly seen in this test.
Treatment[edit]
The treatment for conditions that cause the presence of elliptocytes in the blood depends on the underlying condition. For example, in the case of hereditary elliptocytosis, treatment may not be necessary unless the condition is severe. In severe cases, a blood transfusion may be required.
Images[edit]
-
Hereditary Elliptocytosis in a 70-year-old man -
Poikilocytes - Red blood cell types
