Second-impact syndrome: Difference between revisions

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== Second-Impact Syndrome (SIS) ==
{{SI}}
 
{{Infobox medical condition
| name            = Second-impact syndrome
| image          = [[File:Concussion_Anatomy.png|250px]]
| caption        = Diagram showing the anatomy of a concussion, which is related to second-impact syndrome
| field          = [[Neurology]], [[Sports medicine]]
| symptoms        = Rapid brain swelling, loss of consciousness, dilated pupils, respiratory failure
| complications  = [[Brain herniation]], [[Coma]], [[Death]]
| onset          = Seconds to minutes after second impact
| duration        = Acute
| causes          = Second [[concussion]] before symptoms of a first concussion have resolved
| risks          = [[Contact sports]], insufficient recovery time after initial concussion
| diagnosis      = Clinical evaluation, history of recent head injury
| differential    = [[Epidural hematoma]], [[Subdural hematoma]], [[Cerebral contusion]]
| prevention      = Proper management of initial concussion, adherence to return-to-play guidelines
| treatment      = Emergency medical care, [[Intubation]], [[Surgery]] if necessary
| prognosis      = Poor if not treated immediately
| frequency      = Rare
}}
Second-Impact Syndrome (SIS) is a critical and often catastrophic medical condition that occurs when an individual suffers a second concussion before the symptoms from a previous concussion have fully subsided. This subsequent injury, which can follow the initial concussion by minutes, days, or weeks, leads to rapid and severe brain swelling. SIS can be fatal, and survivors often suffer from severe disabilities.
Second-Impact Syndrome (SIS) is a critical and often catastrophic medical condition that occurs when an individual suffers a second concussion before the symptoms from a previous concussion have fully subsided. This subsequent injury, which can follow the initial concussion by minutes, days, or weeks, leads to rapid and severe brain swelling. SIS can be fatal, and survivors often suffer from severe disabilities.
 
== Introduction ==
[[File:Concussion Anatomy.png|thumb|right|500px|Illustration of a brain concussion, which can lead to Second-Impact Syndrome]]
 
== Overview ==
* SIS involves the swelling of the brain after a second traumatic injury.
* SIS involves the swelling of the brain after a second traumatic injury.
* Even a mild grade of concussion can lead to SIS.
* Even a mild grade of concussion can lead to SIS.
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== Pathophysiology ==
== Pathophysiology ==
* The exact cause of SIS is not entirely understood.
* The exact cause of SIS is not entirely understood.
* It is thought to involve the loss of regulation in the brain's arterioles, leading to uncontrolled cerebral blood flow and subsequent massive cerebral edema.
* It is thought to involve the loss of regulation in the brain's arterioles, leading to uncontrolled cerebral blood flow and subsequent massive cerebral edema.
== Symptoms and Risks ==
== Symptoms and Risks ==
* Symptoms of a concussion that may precede SIS include headache, confusion, dizziness, and memory loss.
* Symptoms of a concussion that may precede SIS include headache, confusion, dizziness, and memory loss.
* The second impact, while it may be mild, triggers severe neurological deterioration.
* The second impact, while it may be mild, triggers severe neurological deterioration.
== Fatal Consequences and Disability ==
== Fatal Consequences and Disability ==
* SIS is frequently fatal due to the rapid increase in intracranial pressure.
* SIS is frequently fatal due to the rapid increase in intracranial pressure.
* Survivors often face long-term severe disabilities.
* Survivors often face long-term severe disabilities.
== Diagnosis and Prevention ==
== Diagnosis and Prevention ==
* Early diagnosis of initial concussion and proper management are key to preventing SIS.
* Early diagnosis of initial concussion and proper management are key to preventing SIS.
* Athletes, particularly in contact sports, should be thoroughly evaluated and must not return to play until fully recovered.
* Athletes, particularly in contact sports, should be thoroughly evaluated and must not return to play until fully recovered.
== Treatment ==
== Treatment ==
* Immediate medical attention is critical for SIS.
* Immediate medical attention is critical for SIS.
* Treatment focuses on managing intracranial pressure and ensuring cerebral perfusion.
* Treatment focuses on managing intracranial pressure and ensuring cerebral perfusion.
== Awareness and Education ==
== Awareness and Education ==
* Awareness about the dangers of returning to physical activities too soon after a concussion is vital.
* Awareness about the dangers of returning to physical activities too soon after a concussion is vital.
* Education on concussion management is essential, particularly in sports settings.
* Education on concussion management is essential, particularly in sports settings.
== See Also ==
== See Also ==
* [[Concussion]]
* [[Concussion]]
* [[Traumatic Brain Injury]]
* [[Traumatic Brain Injury]]
* [[Sports Medicine]]
* [[Sports Medicine]]
== External Links ==
== External Links ==
* [https://www.cdc.gov/traumaticbraininjury/index.html Centers for Disease Control and Prevention: Traumatic Brain Injury]
* [https://www.cdc.gov/traumaticbraininjury/index.html Centers for Disease Control and Prevention: Traumatic Brain Injury]
* [https://www.brainline.org/article/second-impact-syndrome BrainLine: Second Impact Syndrome]
* [https://www.brainline.org/article/second-impact-syndrome BrainLine: Second Impact Syndrome]
== References ==
== References ==
<references/>
<references/>
[[Category:Neurology]]
[[Category:Neurology]]
[[Category:Sports Injuries]]
[[Category:Sports Injuries]]
[[Category:Traumatic Brain Injuries]]
[[Category:Traumatic Brain Injuries]]
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Latest revision as of 06:12, 6 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Second-impact syndrome
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Rapid brain swelling, loss of consciousness, dilated pupils, respiratory failure
Complications Brain herniation, Coma, Death
Onset Seconds to minutes after second impact
Duration Acute
Types N/A
Causes Second concussion before symptoms of a first concussion have resolved
Risks Contact sports, insufficient recovery time after initial concussion
Diagnosis Clinical evaluation, history of recent head injury
Differential diagnosis Epidural hematoma, Subdural hematoma, Cerebral contusion
Prevention Proper management of initial concussion, adherence to return-to-play guidelines
Treatment Emergency medical care, Intubation, Surgery if necessary
Medication N/A
Prognosis Poor if not treated immediately
Frequency Rare
Deaths N/A


Second-Impact Syndrome (SIS) is a critical and often catastrophic medical condition that occurs when an individual suffers a second concussion before the symptoms from a previous concussion have fully subsided. This subsequent injury, which can follow the initial concussion by minutes, days, or weeks, leads to rapid and severe brain swelling. SIS can be fatal, and survivors often suffer from severe disabilities.

Introduction[edit]

  • SIS involves the swelling of the brain after a second traumatic injury.
  • Even a mild grade of concussion can lead to SIS.

Pathophysiology[edit]

  • The exact cause of SIS is not entirely understood.
  • It is thought to involve the loss of regulation in the brain's arterioles, leading to uncontrolled cerebral blood flow and subsequent massive cerebral edema.

Symptoms and Risks[edit]

  • Symptoms of a concussion that may precede SIS include headache, confusion, dizziness, and memory loss.
  • The second impact, while it may be mild, triggers severe neurological deterioration.

Fatal Consequences and Disability[edit]

  • SIS is frequently fatal due to the rapid increase in intracranial pressure.
  • Survivors often face long-term severe disabilities.

Diagnosis and Prevention[edit]

  • Early diagnosis of initial concussion and proper management are key to preventing SIS.
  • Athletes, particularly in contact sports, should be thoroughly evaluated and must not return to play until fully recovered.

Treatment[edit]

  • Immediate medical attention is critical for SIS.
  • Treatment focuses on managing intracranial pressure and ensuring cerebral perfusion.

Awareness and Education[edit]

  • Awareness about the dangers of returning to physical activities too soon after a concussion is vital.
  • Education on concussion management is essential, particularly in sports settings.

See Also[edit]

External Links[edit]

References[edit]

<references/>

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