Fibrofolliculoma: Difference between revisions
No edit summary |
CSV import |
||
| Line 1: | Line 1: | ||
{{SI}} | |||
{{Infobox medical condition | |||
| name = Fibrofolliculoma | |||
| image = [[File:Birt–Hogg–Dubé_syndrome.jpg|250px]] | |||
| caption = Fibrofolliculomas on the face of a patient with [[Birt–Hogg–Dubé syndrome]] | |||
| synonyms = | |||
| pronounce = | |||
| specialty = [[Dermatology]] | |||
| symptoms = Small, dome-shaped papules on the face, neck, and upper trunk | |||
| complications = | |||
| onset = Usually in adulthood | |||
| duration = | |||
| types = | |||
| causes = Genetic mutation in the [[FLCN]] gene | |||
| risks = | |||
| diagnosis = Clinical examination, [[skin biopsy]] | |||
| differential = [[Trichodiscoma]], [[Angiofibroma]], [[Basal cell carcinoma]] | |||
| prevention = | |||
| treatment = [[Laser therapy]], [[Surgical excision]] | |||
| medication = | |||
| prognosis = Generally benign | |||
| frequency = Rare | |||
| deaths = | |||
}} | |||
'''Fibrofolliculoma''' is a benign skin lesion that is associated with [[Birt-Hogg-Dubé syndrome]]. It is characterized by a proliferation of fibrous tissue around a hair follicle. | '''Fibrofolliculoma''' is a benign skin lesion that is associated with [[Birt-Hogg-Dubé syndrome]]. It is characterized by a proliferation of fibrous tissue around a hair follicle. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
Fibrofolliculomas typically present as small, skin-colored papules on the face, neck, and upper trunk. They are usually asymptomatic, but can sometimes cause cosmetic concern due to their appearance. | Fibrofolliculomas typically present as small, skin-colored papules on the face, neck, and upper trunk. They are usually asymptomatic, but can sometimes cause cosmetic concern due to their appearance. | ||
==Pathogenesis== | ==Pathogenesis== | ||
The exact pathogenesis of fibrofolliculomas is not fully understood. However, they are known to be associated with mutations in the [[Folliculin]] gene, which is also implicated in Birt-Hogg-Dubé syndrome. | The exact pathogenesis of fibrofolliculomas is not fully understood. However, they are known to be associated with mutations in the [[Folliculin]] gene, which is also implicated in Birt-Hogg-Dubé syndrome. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of fibrofolliculomas is typically made based on clinical examination and confirmed with histopathological examination. The characteristic histological feature is a proliferation of fibrous tissue around a hair follicle. | Diagnosis of fibrofolliculomas is typically made based on clinical examination and confirmed with histopathological examination. The characteristic histological feature is a proliferation of fibrous tissue around a hair follicle. | ||
==Treatment== | ==Treatment== | ||
Treatment of fibrofolliculomas is usually not necessary unless they are causing cosmetic concern. In such cases, they can be removed with surgical excision or laser treatment. | Treatment of fibrofolliculomas is usually not necessary unless they are causing cosmetic concern. In such cases, they can be removed with surgical excision or laser treatment. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for fibrofolliculomas is generally good, as they are benign lesions. However, they can be a marker for Birt-Hogg-Dubé syndrome, which can have more serious implications. | The prognosis for fibrofolliculomas is generally good, as they are benign lesions. However, they can be a marker for Birt-Hogg-Dubé syndrome, which can have more serious implications. | ||
==See Also== | ==See Also== | ||
* [[Birt-Hogg-Dubé syndrome]] | * [[Birt-Hogg-Dubé syndrome]] | ||
* [[Folliculin]] | * [[Folliculin]] | ||
* [[Skin lesion]] | * [[Skin lesion]] | ||
==References== | ==References== | ||
<references /> | <references /> | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
[[Category:Benign neoplasms]] | [[Category:Benign neoplasms]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 02:19, 6 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Fibrofolliculoma | |
|---|---|
| |
| Synonyms | |
| Pronounce | |
| Specialty | Dermatology |
| Symptoms | Small, dome-shaped papules on the face, neck, and upper trunk |
| Complications | |
| Onset | Usually in adulthood |
| Duration | |
| Types | |
| Causes | Genetic mutation in the FLCN gene |
| Risks | |
| Diagnosis | Clinical examination, skin biopsy |
| Differential diagnosis | Trichodiscoma, Angiofibroma, Basal cell carcinoma |
| Prevention | |
| Treatment | Laser therapy, Surgical excision |
| Medication | |
| Prognosis | Generally benign |
| Frequency | Rare |
| Deaths | |
Fibrofolliculoma is a benign skin lesion that is associated with Birt-Hogg-Dubé syndrome. It is characterized by a proliferation of fibrous tissue around a hair follicle.
Clinical Presentation[edit]
Fibrofolliculomas typically present as small, skin-colored papules on the face, neck, and upper trunk. They are usually asymptomatic, but can sometimes cause cosmetic concern due to their appearance.
Pathogenesis[edit]
The exact pathogenesis of fibrofolliculomas is not fully understood. However, they are known to be associated with mutations in the Folliculin gene, which is also implicated in Birt-Hogg-Dubé syndrome.
Diagnosis[edit]
Diagnosis of fibrofolliculomas is typically made based on clinical examination and confirmed with histopathological examination. The characteristic histological feature is a proliferation of fibrous tissue around a hair follicle.
Treatment[edit]
Treatment of fibrofolliculomas is usually not necessary unless they are causing cosmetic concern. In such cases, they can be removed with surgical excision or laser treatment.
Prognosis[edit]
The prognosis for fibrofolliculomas is generally good, as they are benign lesions. However, they can be a marker for Birt-Hogg-Dubé syndrome, which can have more serious implications.
See Also[edit]
References[edit]
<references />
