Basidiobolomycosis: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Basidiobolomycosis | |||
| image = [[File:Basidiobolus_(257_20).jpg|left|thumb|Basidiobolus under a microscope]] | |||
| caption = ''Basidiobolus'' under a microscope | |||
| field = [[Infectious disease]] | |||
| symptoms = [[Subcutaneous swelling]], [[gastrointestinal symptoms]] | |||
| complications = [[Bowel obstruction]], [[perforation]] | |||
| onset = Gradual | |||
| duration = Chronic | |||
| causes = ''[[Basidiobolus ranarum]]'' infection | |||
| risks = [[Immunocompromised state]], [[tropical climate]] | |||
| diagnosis = [[Biopsy]], [[culture]], [[imaging studies]] | |||
| differential = [[Other fungal infections]], [[bacterial infections]] | |||
| treatment = [[Antifungal medication]], [[surgical intervention]] | |||
| medication = [[Itraconazole]], [[amphotericin B]] | |||
| prognosis = Variable, depends on early diagnosis and treatment | |||
| frequency = Rare | |||
}} | |||
'''Basidiobolomycosis''' is a rare [[infectious disease]] caused by the fungus ''[[Basidiobolus ranarum]]''. This fungus is part of the [[Zygomycota]] phylum and is typically found in the soil and decaying organic matter. It is most commonly found in tropical and subtropical regions. | '''Basidiobolomycosis''' is a rare [[infectious disease]] caused by the fungus ''[[Basidiobolus ranarum]]''. This fungus is part of the [[Zygomycota]] phylum and is typically found in the soil and decaying organic matter. It is most commonly found in tropical and subtropical regions. | ||
[[File:Basidiobolus (257 20).jpg|left|thumb|alt=Basidiobolus_(257_20)]] | |||
[[File:Basidiobolus (257 20).jpg|thumb|alt=Basidiobolus_(257_20)]] | |||
==Etiology== | ==Etiology== | ||
The primary cause of Basidiobolomycosis is the fungus ''Basidiobolus ranarum''. This fungus is found in the environment, particularly in soil and decaying organic matter. It is also found in the gastrointestinal tract of healthy reptiles, amphibians, fish, and insectivorous bats. Humans can become infected through the skin, often through minor trauma or insect bites. | The primary cause of Basidiobolomycosis is the fungus ''Basidiobolus ranarum''. This fungus is found in the environment, particularly in soil and decaying organic matter. It is also found in the gastrointestinal tract of healthy reptiles, amphibians, fish, and insectivorous bats. Humans can become infected through the skin, often through minor trauma or insect bites. | ||
==Symptoms== | ==Symptoms== | ||
The symptoms of Basidiobolomycosis can vary depending on the site of infection. The most common form of the disease is cutaneous Basidiobolomycosis, which affects the skin and subcutaneous tissues. Symptoms can include skin lesions, nodules, or plaques that are often painless but can be accompanied by mild tenderness. In rare cases, the disease can also affect the gastrointestinal tract, causing symptoms such as abdominal pain, nausea, vomiting, and weight loss. | The symptoms of Basidiobolomycosis can vary depending on the site of infection. The most common form of the disease is cutaneous Basidiobolomycosis, which affects the skin and subcutaneous tissues. Symptoms can include skin lesions, nodules, or plaques that are often painless but can be accompanied by mild tenderness. In rare cases, the disease can also affect the gastrointestinal tract, causing symptoms such as abdominal pain, nausea, vomiting, and weight loss. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of Basidiobolomycosis is often challenging due to its rarity and non-specific symptoms. It is typically confirmed through histopathological examination of tissue samples, which can reveal the presence of the fungus. Other diagnostic methods can include culture of the fungus from clinical specimens and molecular techniques such as polymerase chain reaction (PCR). | Diagnosis of Basidiobolomycosis is often challenging due to its rarity and non-specific symptoms. It is typically confirmed through histopathological examination of tissue samples, which can reveal the presence of the fungus. Other diagnostic methods can include culture of the fungus from clinical specimens and molecular techniques such as polymerase chain reaction (PCR). | ||
==Treatment== | ==Treatment== | ||
Treatment for Basidiobolomycosis typically involves long-term antifungal therapy. The antifungal drug itraconazole is most commonly used, often for a period of several months. In severe cases, surgical intervention may be necessary to remove infected tissue. | Treatment for Basidiobolomycosis typically involves long-term antifungal therapy. The antifungal drug itraconazole is most commonly used, often for a period of several months. In severe cases, surgical intervention may be necessary to remove infected tissue. | ||
==Epidemiology== | ==Epidemiology== | ||
Basidiobolomycosis is most commonly reported in tropical and subtropical regions, particularly in Africa, Asia, and South America. However, cases have been reported worldwide. The disease affects both children and adults, with a slight male predominance. | Basidiobolomycosis is most commonly reported in tropical and subtropical regions, particularly in Africa, Asia, and South America. However, cases have been reported worldwide. The disease affects both children and adults, with a slight male predominance. | ||
==See also== | ==See also== | ||
* [[Mycosis]] | * [[Mycosis]] | ||
* [[Zygomycosis]] | * [[Zygomycosis]] | ||
* [[Fungal diseases]] | * [[Fungal diseases]] | ||
==References== | ==References== | ||
<references /> | <references /> | ||
{{medicine-stub}} | {{medicine-stub}} | ||
[[Category:Infectious diseases]] | [[Category:Infectious diseases]] | ||
[[Category:Mycoses]] | [[Category:Mycoses]] | ||
[[Category:Tropical diseases]] | [[Category:Tropical diseases]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
Latest revision as of 19:37, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
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| Basidiobolomycosis | |
|---|---|
.jpg) | |
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Subcutaneous swelling, gastrointestinal symptoms |
| Complications | Bowel obstruction, perforation |
| Onset | Gradual |
| Duration | Chronic |
| Types | N/A |
| Causes | Basidiobolus ranarum infection |
| Risks | Immunocompromised state, tropical climate |
| Diagnosis | Biopsy, culture, imaging studies |
| Differential diagnosis | Other fungal infections, bacterial infections |
| Prevention | N/A |
| Treatment | Antifungal medication, surgical intervention |
| Medication | Itraconazole, amphotericin B |
| Prognosis | Variable, depends on early diagnosis and treatment |
| Frequency | Rare |
| Deaths | N/A |
Basidiobolomycosis is a rare infectious disease caused by the fungus Basidiobolus ranarum. This fungus is part of the Zygomycota phylum and is typically found in the soil and decaying organic matter. It is most commonly found in tropical and subtropical regions.
Etiology[edit]
The primary cause of Basidiobolomycosis is the fungus Basidiobolus ranarum. This fungus is found in the environment, particularly in soil and decaying organic matter. It is also found in the gastrointestinal tract of healthy reptiles, amphibians, fish, and insectivorous bats. Humans can become infected through the skin, often through minor trauma or insect bites.
Symptoms[edit]
The symptoms of Basidiobolomycosis can vary depending on the site of infection. The most common form of the disease is cutaneous Basidiobolomycosis, which affects the skin and subcutaneous tissues. Symptoms can include skin lesions, nodules, or plaques that are often painless but can be accompanied by mild tenderness. In rare cases, the disease can also affect the gastrointestinal tract, causing symptoms such as abdominal pain, nausea, vomiting, and weight loss.
Diagnosis[edit]
Diagnosis of Basidiobolomycosis is often challenging due to its rarity and non-specific symptoms. It is typically confirmed through histopathological examination of tissue samples, which can reveal the presence of the fungus. Other diagnostic methods can include culture of the fungus from clinical specimens and molecular techniques such as polymerase chain reaction (PCR).
Treatment[edit]
Treatment for Basidiobolomycosis typically involves long-term antifungal therapy. The antifungal drug itraconazole is most commonly used, often for a period of several months. In severe cases, surgical intervention may be necessary to remove infected tissue.
Epidemiology[edit]
Basidiobolomycosis is most commonly reported in tropical and subtropical regions, particularly in Africa, Asia, and South America. However, cases have been reported worldwide. The disease affects both children and adults, with a slight male predominance.
See also[edit]
References[edit]
<references />
