Brittle asthma: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Brittle asthma
| image          = [[File:Asthma_(Lungs).png|250px]]
| caption        = Diagram of the lungs affected by asthma
| field          = [[Pulmonology]]
| symptoms        = Severe [[asthma]] attacks, [[wheezing]], [[shortness of breath]], [[coughing]]
| complications  = [[Respiratory failure]], [[pneumothorax]], [[status asthmaticus]]
| onset          = Typically in [[childhood]] or [[adolescence]]
| duration        = Chronic
| types          = Type 1 (wide peak flow variability), Type 2 (sudden severe attacks)
| causes          = [[Allergens]], [[respiratory infections]], [[exercise]], [[stress]]
| risks          = Poorly controlled asthma, [[allergy]], [[smoking]], [[family history]]
| diagnosis      = [[Spirometry]], [[peak flow monitoring]], [[allergy testing]]
| differential    = [[Chronic obstructive pulmonary disease]], [[vocal cord dysfunction]], [[heart failure]]
| prevention      = Avoidance of triggers, regular use of [[inhaled corticosteroids]]
| treatment      = [[Bronchodilators]], [[corticosteroids]], [[biologics]], [[oxygen therapy]]
| medication      = [[Salbutamol]], [[prednisone]], [[omalizumab]]
| prognosis      = Variable; can be life-threatening if not managed
| frequency      = Rare
}}
{{Short description|A severe form of asthma characterized by sudden and severe attacks}}
{{Short description|A severe form of asthma characterized by sudden and severe attacks}}
 
[[File:Asthma_(Lungs).png|left|thumb|Diagram of the lungs affected by asthma]]
[[File:Asthma_(Lungs).png|thumb|right|Diagram of the lungs affected by asthma]]
 
'''Brittle asthma''' is a rare and severe form of [[asthma]] that is characterized by sudden and severe attacks that can be life-threatening. It is distinguished from other forms of asthma by its unpredictability and the difficulty in controlling symptoms with standard treatments.
'''Brittle asthma''' is a rare and severe form of [[asthma]] that is characterized by sudden and severe attacks that can be life-threatening. It is distinguished from other forms of asthma by its unpredictability and the difficulty in controlling symptoms with standard treatments.
==Types==
==Types==
Brittle asthma is classified into two types:
Brittle asthma is classified into two types:
===Type 1 Brittle Asthma===
===Type 1 Brittle Asthma===
Type 1 brittle asthma is characterized by a wide variation in peak expiratory flow (PEF) despite intense medical therapy. Patients with this type experience frequent and severe asthma attacks that can occur suddenly and without warning.
Type 1 brittle asthma is characterized by a wide variation in peak expiratory flow (PEF) despite intense medical therapy. Patients with this type experience frequent and severe asthma attacks that can occur suddenly and without warning.
===Type 2 Brittle Asthma===
===Type 2 Brittle Asthma===
Type 2 brittle asthma involves sudden, severe attacks on a background of otherwise well-controlled asthma. These attacks can be life-threatening and require immediate medical attention.
Type 2 brittle asthma involves sudden, severe attacks on a background of otherwise well-controlled asthma. These attacks can be life-threatening and require immediate medical attention.
==Symptoms==
==Symptoms==
The symptoms of brittle asthma are similar to those of other forms of asthma but are more severe and unpredictable. They include:
The symptoms of brittle asthma are similar to those of other forms of asthma but are more severe and unpredictable. They include:
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* Chest tightness
* Chest tightness
* Rapid deterioration of lung function
* Rapid deterioration of lung function
==Causes==
==Causes==
The exact cause of brittle asthma is not well understood, but it is believed to involve a combination of genetic, environmental, and immunological factors. Triggers can include:
The exact cause of brittle asthma is not well understood, but it is believed to involve a combination of genetic, environmental, and immunological factors. Triggers can include:
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* [[Stress]]
* [[Stress]]
* [[Exercise]]
* [[Exercise]]
==Diagnosis==
==Diagnosis==
Diagnosis of brittle asthma involves a thorough medical history, physical examination, and lung function tests. It is important to distinguish brittle asthma from other forms of severe asthma to tailor appropriate treatment strategies.
Diagnosis of brittle asthma involves a thorough medical history, physical examination, and lung function tests. It is important to distinguish brittle asthma from other forms of severe asthma to tailor appropriate treatment strategies.
==Treatment==
==Treatment==
Treatment of brittle asthma is challenging and often requires a multidisciplinary approach. It may include:
Treatment of brittle asthma is challenging and often requires a multidisciplinary approach. It may include:
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* [[Oxygen therapy]]
* [[Oxygen therapy]]
* [[Hospitalization]] during severe attacks
* [[Hospitalization]] during severe attacks
==Prognosis==
==Prognosis==
The prognosis for individuals with brittle asthma varies. With appropriate management, some patients can achieve better control of their symptoms, but the condition can be life-threatening if not properly managed.
The prognosis for individuals with brittle asthma varies. With appropriate management, some patients can achieve better control of their symptoms, but the condition can be life-threatening if not properly managed.
==Prevention==
==Prevention==
Preventive measures for brittle asthma focus on avoiding known triggers and adhering to prescribed treatment plans. Regular follow-up with healthcare providers is essential to monitor and adjust treatment as needed.
Preventive measures for brittle asthma focus on avoiding known triggers and adhering to prescribed treatment plans. Regular follow-up with healthcare providers is essential to monitor and adjust treatment as needed.
 
==See also==
==Related pages==
* [[Asthma]]
* [[Asthma]]
* [[Chronic obstructive pulmonary disease]]
* [[Chronic obstructive pulmonary disease]]
* [[Respiratory therapy]]
* [[Respiratory therapy]]
[[Category:Asthma]]
[[Category:Asthma]]
[[Category:Respiratory diseases]]
[[Category:Respiratory diseases]]

Latest revision as of 18:57, 4 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Brittle asthma
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Severe asthma attacks, wheezing, shortness of breath, coughing
Complications Respiratory failure, pneumothorax, status asthmaticus
Onset Typically in childhood or adolescence
Duration Chronic
Types Type 1 (wide peak flow variability), Type 2 (sudden severe attacks)
Causes Allergens, respiratory infections, exercise, stress
Risks Poorly controlled asthma, allergy, smoking, family history
Diagnosis Spirometry, peak flow monitoring, allergy testing
Differential diagnosis Chronic obstructive pulmonary disease, vocal cord dysfunction, heart failure
Prevention Avoidance of triggers, regular use of inhaled corticosteroids
Treatment Bronchodilators, corticosteroids, biologics, oxygen therapy
Medication Salbutamol, prednisone, omalizumab
Prognosis Variable; can be life-threatening if not managed
Frequency Rare
Deaths N/A


A severe form of asthma characterized by sudden and severe attacks


Diagram of the lungs affected by asthma

Brittle asthma is a rare and severe form of asthma that is characterized by sudden and severe attacks that can be life-threatening. It is distinguished from other forms of asthma by its unpredictability and the difficulty in controlling symptoms with standard treatments.

Types[edit]

Brittle asthma is classified into two types:

Type 1 Brittle Asthma[edit]

Type 1 brittle asthma is characterized by a wide variation in peak expiratory flow (PEF) despite intense medical therapy. Patients with this type experience frequent and severe asthma attacks that can occur suddenly and without warning.

Type 2 Brittle Asthma[edit]

Type 2 brittle asthma involves sudden, severe attacks on a background of otherwise well-controlled asthma. These attacks can be life-threatening and require immediate medical attention.

Symptoms[edit]

The symptoms of brittle asthma are similar to those of other forms of asthma but are more severe and unpredictable. They include:

Causes[edit]

The exact cause of brittle asthma is not well understood, but it is believed to involve a combination of genetic, environmental, and immunological factors. Triggers can include:

Diagnosis[edit]

Diagnosis of brittle asthma involves a thorough medical history, physical examination, and lung function tests. It is important to distinguish brittle asthma from other forms of severe asthma to tailor appropriate treatment strategies.

Treatment[edit]

Treatment of brittle asthma is challenging and often requires a multidisciplinary approach. It may include:

Prognosis[edit]

The prognosis for individuals with brittle asthma varies. With appropriate management, some patients can achieve better control of their symptoms, but the condition can be life-threatening if not properly managed.

Prevention[edit]

Preventive measures for brittle asthma focus on avoiding known triggers and adhering to prescribed treatment plans. Regular follow-up with healthcare providers is essential to monitor and adjust treatment as needed.

See also[edit]