Atrophic gastritis: Difference between revisions
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{{Infobox medical condition | |||
| name = Atrophic gastritis | |||
| image = [[File:Атрофический_гастрит.jpg|left|thumb|Atrophic gastritis]] | |||
| caption = Endoscopic image of atrophic gastritis | |||
| field = [[Gastroenterology]] | |||
| synonyms = Chronic atrophic gastritis | |||
| symptoms = [[Abdominal pain]], [[nausea]], [[vomiting]], [[weight loss]], [[anemia]] | |||
| complications = [[Gastric cancer]], [[pernicious anemia]] | |||
| onset = Gradual | |||
| duration = Long-term | |||
| causes = [[Helicobacter pylori]] infection, [[autoimmune disease]] | |||
| risks = [[Family history]], [[smoking]], [[alcohol consumption]] | |||
| diagnosis = [[Endoscopy]], [[biopsy]], [[blood test]] | |||
| differential = [[Peptic ulcer disease]], [[gastritis]], [[gastric cancer]] | |||
| treatment = [[Antibiotics]], [[vitamin B12 supplementation]], [[proton pump inhibitors]] | |||
| medication = [[Antibiotics]], [[proton pump inhibitors]] | |||
| frequency = Common in older adults | |||
| deaths = Rare, but can lead to complications | |||
}} | |||
= Atrophic Gastritis = | = Atrophic Gastritis = | ||
[[File:Autoimmune atrophic gastritis (H&E), high mag.jpg|left|thumb|Endoscopic view of atrophic gastritis.|link=Atrophic_gastritis]] | |||
[[File:Autoimmune atrophic gastritis (H&E), high mag.jpg|thumb | |||
== Atrophic Gastritis == | == Atrophic Gastritis == | ||
'''Atrophic gastritis''' is a chronic condition characterized by inflammation and progressive wasting away of the stomach lining, leading to the loss of glands that produce stomach acid. | '''Atrophic gastritis''' is a chronic condition characterized by inflammation and progressive wasting away of the stomach lining, leading to the loss of glands that produce stomach acid. | ||
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== Introduction == | |||
== | |||
Atrophic gastritis involves gradual damage and thinning of the gastric mucosa, which is responsible for the production of stomach acid and digestive enzymes. This condition can lead to various digestive problems and nutritional deficiencies. | Atrophic gastritis involves gradual damage and thinning of the gastric mucosa, which is responsible for the production of stomach acid and digestive enzymes. This condition can lead to various digestive problems and nutritional deficiencies. | ||
== Pathophysiology == | == Pathophysiology == | ||
The process of atrophy in the stomach lining involves: | The process of atrophy in the stomach lining involves: | ||
* Inflammation of the gastric mucosa | * Inflammation of the gastric mucosa | ||
* Thinning and loss of the protective layer of the stomach | * Thinning and loss of the protective layer of the stomach | ||
* Reduction or absence of acid-producing gastric glands | * Reduction or absence of acid-producing gastric glands | ||
== Causes == | == Causes == | ||
Atrophic gastritis can be caused by several factors, including: | Atrophic gastritis can be caused by several factors, including: | ||
* [[Helicobacter pylori|Helicobacter pylori infection]], a common cause of chronic gastritis | * [[Helicobacter pylori|Helicobacter pylori infection]], a common cause of chronic gastritis | ||
* Autoimmune reactions, where the body's immune system mistakenly attacks stomach cells | * Autoimmune reactions, where the body's immune system mistakenly attacks stomach cells | ||
* Long-term use of certain medications, such as proton pump inhibitors | * Long-term use of certain medications, such as proton pump inhibitors | ||
== Symptoms == | == Symptoms == | ||
Symptoms of atrophic gastritis can include: | Symptoms of atrophic gastritis can include: | ||
* Abdominal discomfort or pain | * Abdominal discomfort or pain | ||
* Nausea and vomiting | * Nausea and vomiting | ||
| Line 42: | Line 52: | ||
* Loss of appetite | * Loss of appetite | ||
* Weight loss | * Weight loss | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of atrophic gastritis typically involves: | Diagnosis of atrophic gastritis typically involves: | ||
* [[Gastroscopy|Endoscopic examination]] of the stomach | * [[Gastroscopy|Endoscopic examination]] of the stomach | ||
* Biopsy of stomach tissue | * Biopsy of stomach tissue | ||
* Blood tests to detect Helicobacter pylori infection or autoimmune markers | * Blood tests to detect Helicobacter pylori infection or autoimmune markers | ||
== Treatment == | == Treatment == | ||
Treatment options depend on the underlying cause but may include: | Treatment options depend on the underlying cause but may include: | ||
* Antibiotics to treat Helicobacter pylori infection | * Antibiotics to treat Helicobacter pylori infection | ||
* Medications to reduce stomach acid | * Medications to reduce stomach acid | ||
* Dietary changes and supplements to address nutritional deficiencies | * Dietary changes and supplements to address nutritional deficiencies | ||
== Complications == | == Complications == | ||
If left untreated, atrophic gastritis can lead to complications like: | If left untreated, atrophic gastritis can lead to complications like: | ||
* [[Pernicious anemia|Pernicious anemia]] due to vitamin B12 deficiency | * [[Pernicious anemia|Pernicious anemia]] due to vitamin B12 deficiency | ||
* Increased risk of gastric cancer | * Increased risk of gastric cancer | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Digestive Diseases]] | [[Category:Digestive Diseases]] | ||
{{stub}} | {{stub}} | ||
Latest revision as of 17:17, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
Philadelphia medical weight loss and Philadelphia sleep clinics
| Atrophic gastritis | |
|---|---|
| Synonyms | Chronic atrophic gastritis |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, nausea, vomiting, weight loss, anemia |
| Complications | Gastric cancer, pernicious anemia |
| Onset | Gradual |
| Duration | Long-term |
| Types | N/A |
| Causes | Helicobacter pylori infection, autoimmune disease |
| Risks | Family history, smoking, alcohol consumption |
| Diagnosis | Endoscopy, biopsy, blood test |
| Differential diagnosis | Peptic ulcer disease, gastritis, gastric cancer |
| Prevention | N/A |
| Treatment | Antibiotics, vitamin B12 supplementation, proton pump inhibitors |
| Medication | Antibiotics, proton pump inhibitors |
| Prognosis | N/A |
| Frequency | Common in older adults |
| Deaths | Rare, but can lead to complications |
Atrophic Gastritis[edit]
Atrophic Gastritis[edit]
Atrophic gastritis is a chronic condition characterized by inflammation and progressive wasting away of the stomach lining, leading to the loss of glands that produce stomach acid.
Introduction[edit]
Atrophic gastritis involves gradual damage and thinning of the gastric mucosa, which is responsible for the production of stomach acid and digestive enzymes. This condition can lead to various digestive problems and nutritional deficiencies.
Pathophysiology[edit]
The process of atrophy in the stomach lining involves:
- Inflammation of the gastric mucosa
- Thinning and loss of the protective layer of the stomach
- Reduction or absence of acid-producing gastric glands
Causes[edit]
Atrophic gastritis can be caused by several factors, including:
- Helicobacter pylori infection, a common cause of chronic gastritis
- Autoimmune reactions, where the body's immune system mistakenly attacks stomach cells
- Long-term use of certain medications, such as proton pump inhibitors
Symptoms[edit]
Symptoms of atrophic gastritis can include:
- Abdominal discomfort or pain
- Nausea and vomiting
- Bloating and indigestion
- Loss of appetite
- Weight loss
Diagnosis[edit]
Diagnosis of atrophic gastritis typically involves:
- Endoscopic examination of the stomach
- Biopsy of stomach tissue
- Blood tests to detect Helicobacter pylori infection or autoimmune markers
Treatment[edit]
Treatment options depend on the underlying cause but may include:
- Antibiotics to treat Helicobacter pylori infection
- Medications to reduce stomach acid
- Dietary changes and supplements to address nutritional deficiencies
Complications[edit]
If left untreated, atrophic gastritis can lead to complications like:
- Pernicious anemia due to vitamin B12 deficiency
- Increased risk of gastric cancer
 |
 |
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