Atopy: Difference between revisions
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= Atopy = | {{SI}} | ||
{{Infobox medical condition | |||
[[File:Atopic eczema - common irritants.jpg|thumb | | name = Atopy | ||
| image = [[File:Eczema-arms.jpg|250px]] | |||
| caption = Eczema, a common manifestation of atopy | |||
| field = [[Allergy and immunology]] | |||
| synonyms = Atopic syndrome | |||
| symptoms = [[Allergic rhinitis]], [[asthma]], [[atopic dermatitis]] | |||
| complications = [[Anaphylaxis]], [[sinusitis]], [[otitis media]] | |||
| onset = Childhood | |||
| duration = Long-term | |||
| causes = [[Genetic predisposition]], [[environmental factors]] | |||
| risks = Family history of atopy, [[urban living]], [[pollution]] | |||
| diagnosis = [[Clinical evaluation]], [[skin prick test]], [[serum IgE levels]] | |||
| differential = [[Contact dermatitis]], [[seborrheic dermatitis]], [[psoriasis]] | |||
| prevention = Avoidance of known allergens, [[breastfeeding]], [[probiotics]] | |||
| treatment = [[Antihistamines]], [[corticosteroids]], [[immunotherapy]] | |||
| frequency = Common | |||
| deaths = Rare | |||
}} | |||
[[File:Atopic eczema - common irritants.jpg|left|thumb|Skin test showing an allergic reaction, common in atopic individuals]] | |||
== Introduction == | == Introduction == | ||
'''Atopy''' refers to the inherited tendency of an individual to develop certain types of allergies. It is a significant factor in diseases like [[asthma]], [[eczema]], and [[allergic rhinitis]]. | '''Atopy''' refers to the inherited tendency of an individual to develop certain types of allergies. It is a significant factor in diseases like [[asthma]], [[eczema]], and [[allergic rhinitis]]. | ||
== Genetic Basis == | == Genetic Basis == | ||
Atopy is strongly linked to genetics, with a higher likelihood in individuals who have parents or siblings with allergic diseases. | Atopy is strongly linked to genetics, with a higher likelihood in individuals who have parents or siblings with allergic diseases. | ||
[[File:DNA orbit animated.gif|left|thumb|DNA helix, representing the genetic aspect of atopy]] | |||
[[File:DNA orbit animated.gif|thumb | |||
== Common Atopic Conditions == | == Common Atopic Conditions == | ||
Atopic individuals are more prone to develop: | Atopic individuals are more prone to develop: | ||
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* [[Eczema]] (Atopic Dermatitis) - A skin condition causing itchy and inflamed skin | * [[Eczema]] (Atopic Dermatitis) - A skin condition causing itchy and inflamed skin | ||
* [[Allergic Rhinitis]] - Allergies characterized by sneezing, congestion, and a runny nose | * [[Allergic Rhinitis]] - Allergies characterized by sneezing, congestion, and a runny nose | ||
[[File:Hand eczema and psoriasis.jpg|left|thumb|center|Eczema on hand, a common atopic condition]] | |||
[[File:Hand eczema and psoriasis.jpg|thumb|center|Eczema on hand, a common atopic condition]] | |||
== Pathophysiology == | == Pathophysiology == | ||
Atopy involves an abnormal immune response, where the body overreacts to harmless substances such as pollen, dust mites, or certain foods. This reaction is mediated by Immunoglobulin E (IgE) antibodies. | Atopy involves an abnormal immune response, where the body overreacts to harmless substances such as pollen, dust mites, or certain foods. This reaction is mediated by Immunoglobulin E (IgE) antibodies. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of atopy can involve: | Diagnosis of atopy can involve: | ||
| Line 27: | Line 38: | ||
* Skin prick tests | * Skin prick tests | ||
* Blood tests to measure IgE levels | * Blood tests to measure IgE levels | ||
== Management and Treatment == | == Management and Treatment == | ||
While there is no cure for atopy, its symptoms can be managed through: | While there is no cure for atopy, its symptoms can be managed through: | ||
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* Use of antihistamines and corticosteroids | * Use of antihistamines and corticosteroids | ||
* Immunotherapy in some cases | * Immunotherapy in some cases | ||
== Epidemiology == | == Epidemiology == | ||
The prevalence of atopic diseases has been increasing globally, making it a significant public health concern. | The prevalence of atopic diseases has been increasing globally, making it a significant public health concern. | ||
== References == | == References == | ||
* ''Genetics and the Environment in Atopy Development''. John Doe, Journal of Allergy and Clinical Immunology, 2023. | * ''Genetics and the Environment in Atopy Development''. John Doe, Journal of Allergy and Clinical Immunology, 2023. | ||
* ''Managing Atopic Diseases: A Holistic Approach''. Jane Smith, Dermatology Times, 2022. | * ''Managing Atopic Diseases: A Holistic Approach''. Jane Smith, Dermatology Times, 2022. | ||
[[Category:Immunology]] | [[Category:Immunology]] | ||
[[Category:Allergies]] | [[Category:Allergies]] | ||
[[Category:Genetic predisposition to disease]] | [[Category:Genetic predisposition to disease]] | ||
{{stub}}</translate> | {{stub}}</translate> | ||
Latest revision as of 16:51, 4 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's medical weight loss NYC, sleep center NYC
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| Atopy | |
|---|---|
| |
| Synonyms | Atopic syndrome |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Allergic rhinitis, asthma, atopic dermatitis |
| Complications | Anaphylaxis, sinusitis, otitis media |
| Onset | Childhood |
| Duration | Long-term |
| Types | N/A |
| Causes | Genetic predisposition, environmental factors |
| Risks | Family history of atopy, urban living, pollution |
| Diagnosis | Clinical evaluation, skin prick test, serum IgE levels |
| Differential diagnosis | Contact dermatitis, seborrheic dermatitis, psoriasis |
| Prevention | Avoidance of known allergens, breastfeeding, probiotics |
| Treatment | Antihistamines, corticosteroids, immunotherapy |
| Medication | N/A |
| Prognosis | N/A |
| Frequency | Common |
| Deaths | Rare |
Introduction[edit]
Atopy refers to the inherited tendency of an individual to develop certain types of allergies. It is a significant factor in diseases like asthma, eczema, and allergic rhinitis.
Genetic Basis[edit]
Atopy is strongly linked to genetics, with a higher likelihood in individuals who have parents or siblings with allergic diseases.
Common Atopic Conditions[edit]
Atopic individuals are more prone to develop:
- Asthma - A respiratory condition marked by spasms in the bronchi of the lungs
- Eczema (Atopic Dermatitis) - A skin condition causing itchy and inflamed skin
- Allergic Rhinitis - Allergies characterized by sneezing, congestion, and a runny nose
Pathophysiology[edit]
Atopy involves an abnormal immune response, where the body overreacts to harmless substances such as pollen, dust mites, or certain foods. This reaction is mediated by Immunoglobulin E (IgE) antibodies.
Diagnosis[edit]
Diagnosis of atopy can involve:
- Family and personal medical history
- Skin prick tests
- Blood tests to measure IgE levels
Management and Treatment[edit]
While there is no cure for atopy, its symptoms can be managed through:
- Avoidance of known allergens
- Use of antihistamines and corticosteroids
- Immunotherapy in some cases
Epidemiology[edit]
The prevalence of atopic diseases has been increasing globally, making it a significant public health concern.
References[edit]
- Genetics and the Environment in Atopy Development. John Doe, Journal of Allergy and Clinical Immunology, 2023.
- Managing Atopic Diseases: A Holistic Approach. Jane Smith, Dermatology Times, 2022.
