Comedocarcinoma: Difference between revisions
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{{Infobox medical condition | |||
| name = Comedocarcinoma | |||
| synonyms = [[Ductal carcinoma in situ]] (DCIS), [[Comedo-type carcinoma]] | |||
| field = [[Oncology]] | |||
| symptoms = Often asymptomatic, may present as a palpable mass or abnormal [[mammogram]] | |||
| complications = [[Invasive breast cancer]] | |||
| onset = Typically in [[postmenopausal]] women | |||
| duration = Variable, can progress to invasive cancer if untreated | |||
| causes = [[Genetic mutations]], [[hormonal factors]], [[environmental factors]] | |||
| risks = [[Family history of breast cancer]], [[BRCA1]]/[[BRCA2]] mutations, [[hormone replacement therapy]] | |||
| diagnosis = [[Mammography]], [[biopsy]], [[histopathological examination]] | |||
| differential = [[Invasive ductal carcinoma]], [[lobular carcinoma in situ]], [[fibroadenoma]] | |||
| prevention = [[Regular screening]], [[lifestyle modifications]], [[chemoprevention]] | |||
| treatment = [[Surgery]], [[radiation therapy]], [[hormonal therapy]] | |||
| prognosis = Excellent with treatment, risk of progression to invasive cancer if untreated | |||
| frequency = Common among [[breast cancer]] cases | |||
}} | |||
'''Comedocarcinoma''' is a subtype of [[ductal carcinoma in situ]] (DCIS), a non-invasive form of [[breast cancer]]. It is characterized by the presence of [[comedo necrosis]], a specific type of cell death in which the cell's contents are expelled, resembling a comedo (a blackhead). | '''Comedocarcinoma''' is a subtype of [[ductal carcinoma in situ]] (DCIS), a non-invasive form of [[breast cancer]]. It is characterized by the presence of [[comedo necrosis]], a specific type of cell death in which the cell's contents are expelled, resembling a comedo (a blackhead). | ||
==Overview== | ==Overview== | ||
Comedocarcinoma is a high-grade form of DCIS, meaning it has a higher likelihood of becoming invasive if left untreated. It is named for its resemblance to a comedo, a blackhead, under the microscope. The center of the tumor is filled with dead cells and debris, which can be expressed out, similar to a blackhead. | Comedocarcinoma is a high-grade form of DCIS, meaning it has a higher likelihood of becoming invasive if left untreated. It is named for its resemblance to a comedo, a blackhead, under the microscope. The center of the tumor is filled with dead cells and debris, which can be expressed out, similar to a blackhead. | ||
==Symptoms== | ==Symptoms== | ||
Comedocarcinoma typically does not present with any symptoms. It is most often discovered during routine [[mammography]]. In some cases, it may present as a palpable mass in the breast or nipple discharge. | Comedocarcinoma typically does not present with any symptoms. It is most often discovered during routine [[mammography]]. In some cases, it may present as a palpable mass in the breast or nipple discharge. | ||
==Diagnosis== | ==Diagnosis== | ||
The diagnosis of comedocarcinoma is made by [[biopsy]] of the suspicious area identified on mammography. The biopsy sample is then examined under a microscope by a [[pathologist]] who can identify the characteristic features of comedocarcinoma. | The diagnosis of comedocarcinoma is made by [[biopsy]] of the suspicious area identified on mammography. The biopsy sample is then examined under a microscope by a [[pathologist]] who can identify the characteristic features of comedocarcinoma. | ||
==Treatment== | ==Treatment== | ||
The treatment for comedocarcinoma is similar to other forms of DCIS. This may include [[lumpectomy]] (surgical removal of the tumor and a small amount of surrounding tissue), [[mastectomy]] (surgical removal of the entire breast), and [[radiation therapy]]. In some cases, [[hormone therapy]] may also be recommended. | The treatment for comedocarcinoma is similar to other forms of DCIS. This may include [[lumpectomy]] (surgical removal of the tumor and a small amount of surrounding tissue), [[mastectomy]] (surgical removal of the entire breast), and [[radiation therapy]]. In some cases, [[hormone therapy]] may also be recommended. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for comedocarcinoma is generally good, as it is a non-invasive form of breast cancer. However, it is a high-grade form of DCIS, which means it has a higher likelihood of becoming invasive if left untreated. | The prognosis for comedocarcinoma is generally good, as it is a non-invasive form of breast cancer. However, it is a high-grade form of DCIS, which means it has a higher likelihood of becoming invasive if left untreated. | ||
[[Category:Breast cancer]] | [[Category:Breast cancer]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
==See also== | ==See also== | ||
* [[Breast cancer]] | * [[Breast cancer]] | ||
| Line 32: | Line 42: | ||
* [[Radiation therapy]] | * [[Radiation therapy]] | ||
* [[Hormone therapy]] | * [[Hormone therapy]] | ||
==References== | ==References== | ||
<references /> | <references /> | ||
==External links== | ==External links== | ||
* [http://www.cancer.gov/types/breast National Cancer Institute: Breast Cancer] | * [http://www.cancer.gov/types/breast National Cancer Institute: Breast Cancer] | ||
* [http://www.breastcancer.org/ BreastCancer.org] | * [http://www.breastcancer.org/ BreastCancer.org] | ||
[[Category:Breast cancer]] | [[Category:Breast cancer]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Oncology]] | [[Category:Oncology]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 04:17, 4 April 2025
| Comedocarcinoma | |
|---|---|
| Synonyms | Ductal carcinoma in situ (DCIS), Comedo-type carcinoma |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Often asymptomatic, may present as a palpable mass or abnormal mammogram |
| Complications | Invasive breast cancer |
| Onset | Typically in postmenopausal women |
| Duration | Variable, can progress to invasive cancer if untreated |
| Types | N/A |
| Causes | Genetic mutations, hormonal factors, environmental factors |
| Risks | Family history of breast cancer, BRCA1/BRCA2 mutations, hormone replacement therapy |
| Diagnosis | Mammography, biopsy, histopathological examination |
| Differential diagnosis | Invasive ductal carcinoma, lobular carcinoma in situ, fibroadenoma |
| Prevention | Regular screening, lifestyle modifications, chemoprevention |
| Treatment | Surgery, radiation therapy, hormonal therapy |
| Medication | N/A |
| Prognosis | Excellent with treatment, risk of progression to invasive cancer if untreated |
| Frequency | Common among breast cancer cases |
| Deaths | N/A |
Comedocarcinoma is a subtype of ductal carcinoma in situ (DCIS), a non-invasive form of breast cancer. It is characterized by the presence of comedo necrosis, a specific type of cell death in which the cell's contents are expelled, resembling a comedo (a blackhead).
Overview[edit]
Comedocarcinoma is a high-grade form of DCIS, meaning it has a higher likelihood of becoming invasive if left untreated. It is named for its resemblance to a comedo, a blackhead, under the microscope. The center of the tumor is filled with dead cells and debris, which can be expressed out, similar to a blackhead.
Symptoms[edit]
Comedocarcinoma typically does not present with any symptoms. It is most often discovered during routine mammography. In some cases, it may present as a palpable mass in the breast or nipple discharge.
Diagnosis[edit]
The diagnosis of comedocarcinoma is made by biopsy of the suspicious area identified on mammography. The biopsy sample is then examined under a microscope by a pathologist who can identify the characteristic features of comedocarcinoma.
Treatment[edit]
The treatment for comedocarcinoma is similar to other forms of DCIS. This may include lumpectomy (surgical removal of the tumor and a small amount of surrounding tissue), mastectomy (surgical removal of the entire breast), and radiation therapy. In some cases, hormone therapy may also be recommended.
Prognosis[edit]
The prognosis for comedocarcinoma is generally good, as it is a non-invasive form of breast cancer. However, it is a high-grade form of DCIS, which means it has a higher likelihood of becoming invasive if left untreated.
See also[edit]
- Breast cancer
- Ductal carcinoma in situ
- Mammography
- Biopsy
- Pathology
- Lumpectomy
- Mastectomy
- Radiation therapy
- Hormone therapy
References[edit]
<references />
