Opsoclonus: Difference between revisions
No edit summary |
CSV import |
||
| Line 1: | Line 1: | ||
{{Infobox medical condition | |||
| name = Opsoclonus | |||
| synonyms = [[Dancing eyes syndrome]] | |||
| field = [[Neurology]] | |||
| symptoms = Rapid, involuntary eye movements, [[myoclonus]], [[ataxia]], irritability | |||
| complications = [[Sleep disturbances]], [[behavioral changes]], [[developmental delay]] | |||
| onset = Typically in [[infancy]] or early [[childhood]] | |||
| duration = Can be [[chronic]] or [[relapsing]] | |||
| causes = Often associated with [[neuroblastoma]], [[viral infections]], or [[autoimmune disorders]] | |||
| risks = [[Paraneoplastic syndrome]], [[autoimmune response]] | |||
| diagnosis = [[Clinical examination]], [[MRI]], [[CSF analysis]] | |||
| differential = [[Nystagmus]], [[ataxia-telangiectasia]], [[Friedreich's ataxia]] | |||
| treatment = [[Immunotherapy]], [[corticosteroids]], [[intravenous immunoglobulin]] | |||
| prognosis = Variable; some may have long-term [[neurological deficits]] | |||
| frequency = Rare | |||
}} | |||
'''Opsoclonus''' is a medical condition characterized by rapid, involuntary, multivectorial (horizontal and vertical), unpredictable, conjugate fast eye movements without intersaccadic intervals. It is also known as '''opsoclonus-myoclonus syndrome''' (OMS), '''dancing eyes-dancing feet syndrome''', or '''Kinsbourne syndrome'''. This condition is rare, affecting about 1 in 10,000,000 people per year. It is often associated with neuroblastoma in children, and with breast cancer or small-cell lung cancer in adults. | '''Opsoclonus''' is a medical condition characterized by rapid, involuntary, multivectorial (horizontal and vertical), unpredictable, conjugate fast eye movements without intersaccadic intervals. It is also known as '''opsoclonus-myoclonus syndrome''' (OMS), '''dancing eyes-dancing feet syndrome''', or '''Kinsbourne syndrome'''. This condition is rare, affecting about 1 in 10,000,000 people per year. It is often associated with neuroblastoma in children, and with breast cancer or small-cell lung cancer in adults. | ||
==Symptoms== | ==Symptoms== | ||
The primary symptom of opsoclonus is rapid, involuntary eye movement. Other symptoms can include difficulty speaking (dysarthria), difficulties with coordination and balance (ataxia), and, in some cases, a mild encephalopathy. Children with opsoclonus may also exhibit irritability, malaise, and lethargy. | The primary symptom of opsoclonus is rapid, involuntary eye movement. Other symptoms can include difficulty speaking (dysarthria), difficulties with coordination and balance (ataxia), and, in some cases, a mild encephalopathy. Children with opsoclonus may also exhibit irritability, malaise, and lethargy. | ||
==Causes== | ==Causes== | ||
Opsoclonus is often caused by a tumor, most commonly neuroblastoma in children and small-cell lung cancer or breast cancer in adults. It can also be caused by viral or bacterial infections, or it can be idiopathic (of unknown cause). | Opsoclonus is often caused by a tumor, most commonly neuroblastoma in children and small-cell lung cancer or breast cancer in adults. It can also be caused by viral or bacterial infections, or it can be idiopathic (of unknown cause). | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of opsoclonus is primarily based on clinical observation of the characteristic eye movements. Additional tests may be performed to identify potential underlying causes, such as imaging studies to look for tumors, and blood tests to check for signs of infection. | Diagnosis of opsoclonus is primarily based on clinical observation of the characteristic eye movements. Additional tests may be performed to identify potential underlying causes, such as imaging studies to look for tumors, and blood tests to check for signs of infection. | ||
==Treatment== | ==Treatment== | ||
Treatment of opsoclonus typically involves addressing the underlying cause, if one can be identified. This may involve surgery to remove a tumor, or antibiotics to treat an infection. In some cases, immunosuppressive therapy may be used. | Treatment of opsoclonus typically involves addressing the underlying cause, if one can be identified. This may involve surgery to remove a tumor, or antibiotics to treat an infection. In some cases, immunosuppressive therapy may be used. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for opsoclonus varies depending on the underlying cause. If the cause is a tumor, the prognosis is generally good if the tumor can be successfully removed. If the cause is an infection, the prognosis is generally good with appropriate treatment. However, in some cases, opsoclonus can cause permanent neurological damage. | The prognosis for opsoclonus varies depending on the underlying cause. If the cause is a tumor, the prognosis is generally good if the tumor can be successfully removed. If the cause is an infection, the prognosis is generally good with appropriate treatment. However, in some cases, opsoclonus can cause permanent neurological damage. | ||
==See also== | ==See also== | ||
* [[Neuroblastoma]] | * [[Neuroblastoma]] | ||
| Line 23: | Line 34: | ||
* [[Ataxia]] | * [[Ataxia]] | ||
* [[Encephalopathy]] | * [[Encephalopathy]] | ||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Eye diseases]] | [[Category:Eye diseases]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
[[Category:Syndromes]] | [[Category:Syndromes]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 01:11, 4 April 2025
| Opsoclonus | |
|---|---|
| Synonyms | Dancing eyes syndrome |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Rapid, involuntary eye movements, myoclonus, ataxia, irritability |
| Complications | Sleep disturbances, behavioral changes, developmental delay |
| Onset | Typically in infancy or early childhood |
| Duration | Can be chronic or relapsing |
| Types | N/A |
| Causes | Often associated with neuroblastoma, viral infections, or autoimmune disorders |
| Risks | Paraneoplastic syndrome, autoimmune response |
| Diagnosis | Clinical examination, MRI, CSF analysis |
| Differential diagnosis | Nystagmus, ataxia-telangiectasia, Friedreich's ataxia |
| Prevention | N/A |
| Treatment | Immunotherapy, corticosteroids, intravenous immunoglobulin |
| Medication | N/A |
| Prognosis | Variable; some may have long-term neurological deficits |
| Frequency | Rare |
| Deaths | N/A |
Opsoclonus is a medical condition characterized by rapid, involuntary, multivectorial (horizontal and vertical), unpredictable, conjugate fast eye movements without intersaccadic intervals. It is also known as opsoclonus-myoclonus syndrome (OMS), dancing eyes-dancing feet syndrome, or Kinsbourne syndrome. This condition is rare, affecting about 1 in 10,000,000 people per year. It is often associated with neuroblastoma in children, and with breast cancer or small-cell lung cancer in adults.
Symptoms[edit]
The primary symptom of opsoclonus is rapid, involuntary eye movement. Other symptoms can include difficulty speaking (dysarthria), difficulties with coordination and balance (ataxia), and, in some cases, a mild encephalopathy. Children with opsoclonus may also exhibit irritability, malaise, and lethargy.
Causes[edit]
Opsoclonus is often caused by a tumor, most commonly neuroblastoma in children and small-cell lung cancer or breast cancer in adults. It can also be caused by viral or bacterial infections, or it can be idiopathic (of unknown cause).
Diagnosis[edit]
Diagnosis of opsoclonus is primarily based on clinical observation of the characteristic eye movements. Additional tests may be performed to identify potential underlying causes, such as imaging studies to look for tumors, and blood tests to check for signs of infection.
Treatment[edit]
Treatment of opsoclonus typically involves addressing the underlying cause, if one can be identified. This may involve surgery to remove a tumor, or antibiotics to treat an infection. In some cases, immunosuppressive therapy may be used.
Prognosis[edit]
The prognosis for opsoclonus varies depending on the underlying cause. If the cause is a tumor, the prognosis is generally good if the tumor can be successfully removed. If the cause is an infection, the prognosis is generally good with appropriate treatment. However, in some cases, opsoclonus can cause permanent neurological damage.
