Keratinizing metaplasia: Difference between revisions
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{{Infobox medical condition | |||
| name = Keratinizing metaplasia | |||
| synonyms = | |||
| field = [[Pathology]] | |||
| symptoms = [[Dryness]], [[irritation]], [[thickening of tissue]] | |||
| complications = [[Vision impairment]], [[infection]] | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = [[Vitamin A deficiency]], [[chronic irritation]] | |||
| risks = | |||
| diagnosis = [[Biopsy]], [[clinical examination]] | |||
| differential = [[Squamous cell carcinoma]], [[lichen planus]] | |||
| prevention = Adequate [[vitamin A]] intake, avoiding [[chronic irritation]] | |||
| treatment = [[Vitamin A supplementation]], [[topical treatments]] | |||
| medication = | |||
| prognosis = Variable, depending on cause and treatment | |||
| frequency = | |||
| deaths = | |||
}} | |||
'''Keratinizing metaplasia''' is a type of [[metaplasia]] or cellular adaptation, where [[squamous epithelium]] replaces the normal [[epithelium]] of certain body tissues. This process is often associated with chronic irritation or inflammation. | '''Keratinizing metaplasia''' is a type of [[metaplasia]] or cellular adaptation, where [[squamous epithelium]] replaces the normal [[epithelium]] of certain body tissues. This process is often associated with chronic irritation or inflammation. | ||
== Overview == | == Overview == | ||
Keratinizing metaplasia is a pathological process that occurs in response to chronic irritation or inflammation. It is characterized by the replacement of the normal epithelium of certain body tissues with squamous epithelium. This process is often seen in the [[respiratory tract]], [[urinary tract]], and [[cervix]]. | Keratinizing metaplasia is a pathological process that occurs in response to chronic irritation or inflammation. It is characterized by the replacement of the normal epithelium of certain body tissues with squamous epithelium. This process is often seen in the [[respiratory tract]], [[urinary tract]], and [[cervix]]. | ||
== Pathophysiology == | == Pathophysiology == | ||
The exact mechanism of keratinizing metaplasia is not fully understood. However, it is believed to be a response to chronic irritation or inflammation. The normal epithelium of the affected tissue undergoes a transformation into squamous epithelium, a process known as [[metaplasia]]. This new epithelium is more resistant to the irritating or inflammatory conditions, but it may also lose some of the specialized functions of the original tissue. | The exact mechanism of keratinizing metaplasia is not fully understood. However, it is believed to be a response to chronic irritation or inflammation. The normal epithelium of the affected tissue undergoes a transformation into squamous epithelium, a process known as [[metaplasia]]. This new epithelium is more resistant to the irritating or inflammatory conditions, but it may also lose some of the specialized functions of the original tissue. | ||
== Clinical Significance == | == Clinical Significance == | ||
Keratinizing metaplasia is often a precursor to [[cancer]], particularly [[squamous cell carcinoma]]. Therefore, it is important to identify and treat the underlying cause of the chronic irritation or inflammation to prevent the progression to cancer. | Keratinizing metaplasia is often a precursor to [[cancer]], particularly [[squamous cell carcinoma]]. Therefore, it is important to identify and treat the underlying cause of the chronic irritation or inflammation to prevent the progression to cancer. | ||
== See Also == | == See Also == | ||
* [[Metaplasia]] | * [[Metaplasia]] | ||
* [[Squamous cell carcinoma]] | * [[Squamous cell carcinoma]] | ||
* [[Epithelium]] | * [[Epithelium]] | ||
== References == | == References == | ||
<references /> | <references /> | ||
[[Category:Pathology]] | [[Category:Pathology]] | ||
[[Category:Cell biology]] | [[Category:Cell biology]] | ||
Latest revision as of 23:46, 3 April 2025
| Keratinizing metaplasia | |
|---|---|
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Dryness, irritation, thickening of tissue |
| Complications | Vision impairment, infection |
| Onset | |
| Duration | |
| Types | |
| Causes | Vitamin A deficiency, chronic irritation |
| Risks | |
| Diagnosis | Biopsy, clinical examination |
| Differential diagnosis | Squamous cell carcinoma, lichen planus |
| Prevention | Adequate vitamin A intake, avoiding chronic irritation |
| Treatment | Vitamin A supplementation, topical treatments |
| Medication | |
| Prognosis | Variable, depending on cause and treatment |
| Frequency | |
| Deaths | |
Keratinizing metaplasia is a type of metaplasia or cellular adaptation, where squamous epithelium replaces the normal epithelium of certain body tissues. This process is often associated with chronic irritation or inflammation.
Overview[edit]
Keratinizing metaplasia is a pathological process that occurs in response to chronic irritation or inflammation. It is characterized by the replacement of the normal epithelium of certain body tissues with squamous epithelium. This process is often seen in the respiratory tract, urinary tract, and cervix.
Pathophysiology[edit]
The exact mechanism of keratinizing metaplasia is not fully understood. However, it is believed to be a response to chronic irritation or inflammation. The normal epithelium of the affected tissue undergoes a transformation into squamous epithelium, a process known as metaplasia. This new epithelium is more resistant to the irritating or inflammatory conditions, but it may also lose some of the specialized functions of the original tissue.
Clinical Significance[edit]
Keratinizing metaplasia is often a precursor to cancer, particularly squamous cell carcinoma. Therefore, it is important to identify and treat the underlying cause of the chronic irritation or inflammation to prevent the progression to cancer.
See Also[edit]
References[edit]
<references />


