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{{Short description|Network of small blood vessels that supply the walls of large blood vessels}}
== Vasa Vasorum ==
{{Use dmy dates|date=October 2023}}


'''Vasa vasorum''' (Latin for "vessels of the vessels") are small blood vessels that supply the walls of large blood vessels, such as elastic arteries (aorta) and large veins (vena cava). They provide nutrients and oxygen to the outer part of the vessel wall, which is too thick to be nourished by diffusion from the blood in the vessel lumen.
[[File:Cystic_medial_degeneration_-_movat_-_intermed_mag.jpg|Micrograph showing cystic medial degeneration, a condition that can affect the vasa vasorum|thumb|right]]


==Structure==
The '''vasa vasorum''' (Latin for "vessels of the vessels") are a network of small blood vessels that supply the walls of large blood vessels, such as [[arteries]] and [[veins]]. These microvessels are crucial for the nourishment and maintenance of the outer layers of the vessel walls, particularly in large vessels where diffusion from the lumen is insufficient to meet the metabolic needs of the vessel wall.
The vasa vasorum are found in the adventitia and outer part of the media of large arteries and veins. They are more prominent in veins than in arteries, as the walls of veins are generally thicker relative to their lumen size. The vasa vasorum can be classified into three types:


* '''Vasa vasorum interna''': These originate from the main vessel lumen and penetrate the vessel wall.
== Structure ==
* '''Vasa vasorum externa''': These arise from branches of adjacent arteries and veins and supply the outer layers of the vessel wall.
* '''Vasa vasorum venosa''': These drain the blood from the vessel wall into the main vessel lumen or into adjacent veins.


==Function==
The vasa vasorum are typically found in the adventitia and outer part of the media of large arteries and veins. They are more prominent in veins than in arteries due to the lower oxygen content and pressure in venous blood, which necessitates a more extensive network of nourishing vessels. The vasa vasorum can be classified into three types:
The primary function of the vasa vasorum is to supply blood to the outer layers of large blood vessels. This is crucial for maintaining the health and function of the vessel wall, as the inner layers receive nutrients directly from the blood flowing through the vessel lumen. The vasa vasorum also play a role in thermoregulation and in the response to injury or inflammation of the vessel wall.


==Clinical significance==
* '''Vasa vasorum interna''': These originate from the main vessel's lumen and penetrate into the vessel wall.
The vasa vasorum are involved in various pathological conditions. In atherosclerosis, the proliferation of vasa vasorum can contribute to plaque growth and instability. In conditions such as [[Takayasu's arteritis]] and [[Giant cell arteritis]], inflammation of the vasa vasorum can lead to vessel wall damage and stenosis.
* '''Vasa vasorum externa''': These arise from branches of adjacent arteries and supply the outer layers of the vessel wall.
* '''Vasa vasorum venosa''': These drain the blood from the vessel wall into the main vessel or nearby veins.


==Related pages==
== Function ==
 
The primary function of the vasa vasorum is to provide nutrients and oxygen to the cells in the outer layers of large blood vessels, which are too far from the lumen to receive adequate nourishment by diffusion alone. This is particularly important in the [[aorta]], [[vena cava]], and other large vessels where the wall thickness exceeds the diffusion limit for oxygen and nutrients.
 
== Clinical Significance ==
 
The vasa vasorum play a significant role in the pathophysiology of various vascular diseases. For instance, in [[atherosclerosis]], the proliferation of vasa vasorum can contribute to plaque instability and rupture. The vasa vasorum may also be involved in the development of [[aneurysms]], as their dysfunction can lead to ischemia and weakening of the vessel wall.
 
[[File:Cystic_medial_degeneration_-_movat_-_intermed_mag.jpg|Cystic medial degeneration - movat - intermediate magnification|thumb|left]]
 
In conditions such as [[cystic medial degeneration]], the vasa vasorum may be affected, leading to changes in the structural integrity of the vessel wall. This condition is characterized by the degeneration of the elastic tissue in the media of large arteries, which can predispose individuals to aneurysm formation.
 
== Related Pages ==
 
* [[Artery]]
* [[Vein]]
* [[Atherosclerosis]]
* [[Atherosclerosis]]
* [[Arteritis]]
* [[Aneurysm]]
* [[Blood vessel]]
* [[Cystic medial degeneration]]
 
==Gallery==
<gallery>
File:Cystic_medial_degeneration_-_movat_-_intermed_mag.jpg|Micrograph showing cystic medial degeneration, a condition that can affect the vasa vasorum.
</gallery>


==References==
{{Anatomy-stub}}
{{Reflist}}


[[Category:Cardiovascular system]]
[[Category:Cardiovascular system]]
[[Category:Angiology]]
<gallery>
File:Cystic_medial_degeneration_-_movat_-_intermed_mag.jpg|Cystic medial degeneration - movat - intermediate magnification
</gallery>

Latest revision as of 11:07, 23 March 2025

Vasa Vasorum[edit]

Micrograph showing cystic medial degeneration, a condition that can affect the vasa vasorum

The vasa vasorum (Latin for "vessels of the vessels") are a network of small blood vessels that supply the walls of large blood vessels, such as arteries and veins. These microvessels are crucial for the nourishment and maintenance of the outer layers of the vessel walls, particularly in large vessels where diffusion from the lumen is insufficient to meet the metabolic needs of the vessel wall.

Structure[edit]

The vasa vasorum are typically found in the adventitia and outer part of the media of large arteries and veins. They are more prominent in veins than in arteries due to the lower oxygen content and pressure in venous blood, which necessitates a more extensive network of nourishing vessels. The vasa vasorum can be classified into three types:

  • Vasa vasorum interna: These originate from the main vessel's lumen and penetrate into the vessel wall.
  • Vasa vasorum externa: These arise from branches of adjacent arteries and supply the outer layers of the vessel wall.
  • Vasa vasorum venosa: These drain the blood from the vessel wall into the main vessel or nearby veins.

Function[edit]

The primary function of the vasa vasorum is to provide nutrients and oxygen to the cells in the outer layers of large blood vessels, which are too far from the lumen to receive adequate nourishment by diffusion alone. This is particularly important in the aorta, vena cava, and other large vessels where the wall thickness exceeds the diffusion limit for oxygen and nutrients.

Clinical Significance[edit]

The vasa vasorum play a significant role in the pathophysiology of various vascular diseases. For instance, in atherosclerosis, the proliferation of vasa vasorum can contribute to plaque instability and rupture. The vasa vasorum may also be involved in the development of aneurysms, as their dysfunction can lead to ischemia and weakening of the vessel wall.

Cystic medial degeneration - movat - intermediate magnification

In conditions such as cystic medial degeneration, the vasa vasorum may be affected, leading to changes in the structural integrity of the vessel wall. This condition is characterized by the degeneration of the elastic tissue in the media of large arteries, which can predispose individuals to aneurysm formation.

Related Pages[edit]

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