Ligation: Difference between revisions
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Latest revision as of 12:56, 18 March 2025
Ligation is a process that involves the binding or tying of two structures together. It is commonly used in surgery and molecular biology. In surgery, ligation is used to tie off blood vessels to prevent bleeding. In molecular biology, it is used to join together two DNA strands.
Surgical Ligation[edit]
In surgery, ligation is used to tie off blood vessels to prevent bleeding. This is often done using a piece of suture material. The suture is tied around the blood vessel, effectively closing it off and preventing blood from flowing through it. This technique is commonly used in various types of surgeries, including appendectomy, hysterectomy, and vasectomy.
Molecular Ligation[edit]
In molecular biology, ligation is the process of joining together two DNA strands. This is often done using an enzyme called DNA ligase. DNA ligase can join together two DNA strands by forming a phosphodiester bond between them. This process is crucial in the replication and repair of DNA.
Ligation in Other Fields[edit]
Ligation is also used in other fields such as biochemistry and microbiology. In biochemistry, it is used in the process of protein synthesis. In microbiology, it is used in the process of gene cloning.
