Hyperalgesia

Hyperalgesia is an increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves. Temporary increased sensitivity to pain also occurs as part of the body's defense mechanisms during illness or injury.

Causes

Hyperalgesia can be caused by a number of factors, including:

• Inflammation or injury to the skin or other tissues
• Nerve damage or irritation
• Certain medications, such as opioids
• Certain diseases, such as fibromyalgia and migraines

Symptoms

The main symptom of hyperalgesia is an unusually strong reaction to painful stimuli. This can include:

• Increased pain from stimuli that normally cause pain
• Pain from stimuli that do not normally cause pain (allodynia)
• Increased pain from stimuli that are far from the area of injury or inflammation (secondary hyperalgesia)

Treatment

Treatment for hyperalgesia focuses on managing the underlying cause of the increased pain sensitivity. This can include:

• Medications to reduce inflammation and pain
• Physical therapy to help manage pain and improve function
• Psychological therapies, such as cognitive behavioral therapy, to help manage the emotional impact of chronic pain

See also

• Allodynia
• Pain management
• Chronic pain

References

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