Guanoxabenz: Difference between revisions
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Latest revision as of 23:48, 16 March 2025
Guanoxabenz is a drug that is used as an antihypertensive agent. It is a centrally acting alpha-2 adrenergic agonist.
Pharmacology[edit]
Guanoxabenz works by stimulating alpha-2 adrenergic receptors in the brain, which decreases sympathetic nervous system activity and results in lowered blood pressure. It is similar in action to clonidine and methyldopa.
Medical uses[edit]
Guanoxabenz is used for the treatment of hypertension. It can be used alone or in combination with other antihypertensive drugs.
Side effects[edit]
Common side effects of guanoxabenz include drowsiness, dry mouth, and constipation. Less common side effects include depression, insomnia, and palpitations.
Contraindications[edit]
Guanoxabenz is contraindicated in patients with known hypersensitivity to the drug. It should also be used with caution in patients with severe coronary insufficiency, recent myocardial infarction, or cerebrovascular disease.


