Estradiol butyrylacetate

Estradiol Butyrylacetate (also known as EBA) is a synthetic, steroidal estrogen that is used in medicine. It is an ester of estradiol, a naturally occurring estrogen hormone. Estradiol Butyrylacetate is used in hormone therapy for menopausal symptoms and in hormonal contraception.

Chemistry

Estradiol Butyrylacetate is a synthetic estradiol ester. It is formed by the reaction of estradiol with butyric acid and acetic acid. The resulting compound is a steroidal estrogen, similar in structure and function to the natural hormone estradiol.

Pharmacology

Estradiol Butyrylacetate acts as an agonist of the estrogen receptor, the biological target of estrogens. By binding to the estrogen receptor, it stimulates the receptor and produces the same effects as the natural hormone estradiol. These effects include the development and maintenance of female secondary sexual characteristics, regulation of the menstrual cycle, and effects on various other tissues including the bones and the brain.

Medical uses

Estradiol Butyrylacetate is used in medicine for several purposes. It is used in hormone therapy for menopausal symptoms such as hot flashes, vaginal dryness, and osteoporosis. It is also used in hormonal contraception, in combination with a progestogen.

Side effects

Like all estrogens, Estradiol Butyrylacetate can have a number of side effects. These can include nausea, breast tenderness, fluid retention, and an increased risk of certain types of cancer, including breast cancer and endometrial cancer.

See also

• Estradiol
• Estrogen
• Hormone therapy
• Hormonal contraception

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Estradiol butyrylacetate

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  Estradiol butyrylacetate