D-Phenylalanine: Difference between revisions

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== D-Phenylalanine ==
{{Short description|An enantiomer of the amino acid phenylalanine}}


[[File:D-Phenylalanine.svg|D-Phenylalanine structure|thumb|right]]
[[File:D-Phenylalanine.svg|thumb|right|Structural formula of D-Phenylalanine]]


'''D-Phenylalanine''' is an [[enantiomer]] of the [[amino acid]] [[phenylalanine]]. It is one of the two forms of phenylalanine, the other being [[L-phenylalanine]]. While L-phenylalanine is a naturally occurring amino acid found in proteins, D-phenylalanine is not typically found in proteins and is considered a non-proteinogenic amino acid.
'''D-Phenylalanine''' ('''DPA''') is one of the two enantiomers of the amino acid [[phenylalanine]]. It is the D-form, which is the mirror image of the more common L-phenylalanine found in proteins. D-Phenylalanine is not incorporated into proteins but has been studied for its potential therapeutic effects.


== Chemical Properties ==
==Chemical Structure and Properties==
D-Phenylalanine is an [[alpha-amino acid]] with the chemical formula C<sub>9</sub>H<sub>11</sub>NO<sub>2</sub>. It consists of a phenyl group attached to the alpha carbon of an amino acid backbone. The D-configuration refers to the spatial arrangement of the atoms around the chiral center, which is the alpha carbon. This configuration is the opposite of the naturally occurring L-form found in proteins.


D-Phenylalanine has the chemical formula C<sub>9</sub>H<sub>11</sub>NO<sub>2</sub>. It is a [[chiral]] molecule, meaning it has a non-superimposable mirror image. The D- and L- forms of phenylalanine are stereoisomers, differing in the spatial arrangement of atoms around the chiral center.
==Biological Role==
While D-Phenylalanine is not used in the synthesis of proteins, it has been investigated for its potential role in modulating [[pain]] and [[mood]]. It is thought to inhibit the breakdown of [[endorphins]], which are natural pain-relieving compounds in the body. This property has led to research into its use as a supplement for pain management and mood enhancement.


== Biological Role ==
==Therapeutic Uses==
D-Phenylalanine has been explored as a dietary supplement for its potential analgesic effects. Some studies suggest that it may help alleviate chronic pain by inhibiting the enzymes that degrade endorphins, thereby increasing their levels and prolonging their action. However, more research is needed to fully understand its efficacy and safety in clinical settings.


D-Phenylalanine is not incorporated into proteins during [[translation (biology)|protein synthesis]] in living organisms. However, it has been studied for its potential effects on the [[nervous system]]. D-Phenylalanine is thought to inhibit the breakdown of [[endorphins]], which are natural pain-relieving compounds in the body. This has led to research into its use as a potential [[analgesic]] or pain management supplement.
==Synthesis and Production==
D-Phenylalanine can be synthesized through various chemical methods, including the resolution of racemic mixtures of phenylalanine or through enzymatic processes that specifically produce the D-form. It is available as a supplement in various forms, including capsules and powders.


== Medical Uses ==
==Safety and Side Effects==
 
As with any supplement, the safety of D-Phenylalanine depends on the dosage and individual health conditions. It is generally considered safe when used in moderate amounts, but high doses may lead to side effects such as nausea, heartburn, or headaches. Individuals with certain health conditions or those taking specific medications should consult a healthcare provider before using D-Phenylalanine.
D-Phenylalanine has been investigated for its potential therapeutic effects in managing chronic pain conditions. Some studies suggest that it may enhance the effects of endorphins and [[enkephalins]], which are peptides that modulate pain perception. However, more research is needed to fully understand its efficacy and safety in clinical settings.
 
== Synthesis ==
 
D-Phenylalanine can be synthesized through various chemical methods, including the resolution of racemic mixtures of phenylalanine or through asymmetric synthesis techniques. These methods allow for the production of D-phenylalanine in a laboratory setting for research and potential therapeutic use.
 
== Related Compounds ==
 
D-Phenylalanine is related to other amino acids and their derivatives, such as [[L-phenylalanine]], [[tyrosine]], and [[tryptophan]]. These compounds are important in various metabolic pathways and have distinct roles in the body.
 
== Related Pages ==


==Related Pages==
* [[Phenylalanine]]
* [[Phenylalanine]]
* [[Amino acid]]
* [[Amino acid]]
* [[Chirality (chemistry)]]
* [[Enantiomer]]
* [[Analgesic]]
* [[Pain management]]


[[Category:Amino acids]]
[[Category:Amino acids]]
[[Category:Chirality]]
[[Category:Dietary supplements]]
[[Category:Analgesics]]

Latest revision as of 20:51, 5 March 2025

An enantiomer of the amino acid phenylalanine


Structural formula of D-Phenylalanine

D-Phenylalanine (DPA) is one of the two enantiomers of the amino acid phenylalanine. It is the D-form, which is the mirror image of the more common L-phenylalanine found in proteins. D-Phenylalanine is not incorporated into proteins but has been studied for its potential therapeutic effects.

Chemical Structure and Properties[edit]

D-Phenylalanine is an alpha-amino acid with the chemical formula C9H11NO2. It consists of a phenyl group attached to the alpha carbon of an amino acid backbone. The D-configuration refers to the spatial arrangement of the atoms around the chiral center, which is the alpha carbon. This configuration is the opposite of the naturally occurring L-form found in proteins.

Biological Role[edit]

While D-Phenylalanine is not used in the synthesis of proteins, it has been investigated for its potential role in modulating pain and mood. It is thought to inhibit the breakdown of endorphins, which are natural pain-relieving compounds in the body. This property has led to research into its use as a supplement for pain management and mood enhancement.

Therapeutic Uses[edit]

D-Phenylalanine has been explored as a dietary supplement for its potential analgesic effects. Some studies suggest that it may help alleviate chronic pain by inhibiting the enzymes that degrade endorphins, thereby increasing their levels and prolonging their action. However, more research is needed to fully understand its efficacy and safety in clinical settings.

Synthesis and Production[edit]

D-Phenylalanine can be synthesized through various chemical methods, including the resolution of racemic mixtures of phenylalanine or through enzymatic processes that specifically produce the D-form. It is available as a supplement in various forms, including capsules and powders.

Safety and Side Effects[edit]

As with any supplement, the safety of D-Phenylalanine depends on the dosage and individual health conditions. It is generally considered safe when used in moderate amounts, but high doses may lead to side effects such as nausea, heartburn, or headaches. Individuals with certain health conditions or those taking specific medications should consult a healthcare provider before using D-Phenylalanine.

Related Pages[edit]