Naftidrofuryl

Naftidrofuryl (also known as Praxilene) is a vasodilator and antiplatelet agent used for the treatment of peripheral arterial disease (PAD). It works by improving blood flow to the limbs and reducing the stickiness of blood cells, which can cause clots.

Mechanism of Action

Naftidrofuryl is a serotonin antagonist, which means it blocks the action of serotonin, a chemical that can cause blood vessels to narrow. By blocking serotonin, naftidrofuryl helps to widen blood vessels and improve blood flow. It also has antiplatelet properties, which means it can reduce the stickiness of blood cells and prevent them from forming clots.

Uses

Naftidrofuryl is primarily used for the treatment of peripheral arterial disease, a condition in which the arteries that supply blood to the limbs become narrowed or blocked. This can cause symptoms such as pain, cramping, and fatigue, particularly during physical activity. By improving blood flow to the limbs, naftidrofuryl can help to relieve these symptoms.

Side Effects

Like all medicines, naftidrofuryl can cause side effects, although not everyone will experience them. Common side effects include nausea, vomiting, diarrhea, and abdominal pain. If these side effects persist or become severe, patients should contact their healthcare provider.

Contraindications

Naftidrofuryl should not be used by people who are allergic to any of its ingredients. It should also be used with caution in people with a history of bleeding disorders, as it can increase the risk of bleeding.

See Also

• Peripheral artery disease
• Vasodilator
• Antiplatelet

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