Promazine

Promazine is a type of phenothiazine antipsychotic medication, primarily used in the treatment of psychosis and schizophrenia. It is a first-generation antipsychotic, which means it was among the first of its kind to be developed and used in medical practice.

Overview

Promazine works by blocking the action of dopamine, a neurotransmitter in the brain that is involved in mood and behavior. By reducing the activity of dopamine, promazine can help to control symptoms such as hallucinations, delusions, and disorganized thinking that are characteristic of psychotic disorders.

Uses

Promazine is used to treat a variety of conditions, including:

• Schizophrenia
• Psychosis
• Severe nausea and vomiting
• Intractable hiccups

It may also be used as a sedative before surgery or other medical procedures.

Side Effects

Like all medications, promazine can cause side effects. These may include:

• Drowsiness
• Dry mouth
• Blurred vision
• Constipation
• Difficulty urinating
• Changes in heart rate or blood pressure

More serious side effects can include:

• Severe allergic reactions
• Blood disorders
• Liver problems
• Neuroleptic malignant syndrome, a rare but serious condition that can cause high fever, stiff muscles, and changes in consciousness

Precautions

Before taking promazine, it is important to discuss any other medications you are taking with your doctor, as promazine can interact with many other drugs. It is also important to discuss any medical conditions you have, as promazine may not be suitable for people with certain conditions, such as liver disease or heart problems.

See Also

• Phenothiazine
• Antipsychotic
• Dopamine
• Neuroleptic malignant syndrome

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  Promazine chemical structure
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