DTwP-HepB-Hib vaccine

DTwP-HepB-Hib vaccine is a combination vaccine used to protect against diphtheria, tetanus, pertussis, hepatitis B, and Haemophilus influenzae type b (Hib). This vaccine is a part of the World Health Organization's Expanded Program on Immunization (EPI) and is recommended for use in all countries.

Composition

The DTwP-HepB-Hib vaccine contains five different components:

• Diphtheria toxoid (DT): This is a modified form of the toxin produced by the bacterium Corynebacterium diphtheriae. The toxoid stimulates the immune system to produce antibodies against the diphtheria toxin.
• Tetanus toxoid (TT): This is a modified form of the toxin produced by the bacterium Clostridium tetani. The toxoid stimulates the immune system to produce antibodies against the tetanus toxin.
• Whole-cell pertussis vaccine (wP): This is a vaccine made from killed Bordetella pertussis bacteria, which cause whooping cough.
• Hepatitis B vaccine (HepB): This vaccine contains a protein from the surface of the hepatitis B virus, which stimulates the immune system to produce antibodies against the virus.
• Hib vaccine: This vaccine contains a part of the Haemophilus influenzae type b bacterium, which stimulates the immune system to produce antibodies against the bacterium.

Administration

The DTwP-HepB-Hib vaccine is usually given as a series of three injections, at 6, 10, and 14 weeks of age. The vaccine is injected into the muscle of the thigh or upper arm.

Effectiveness

The DTwP-HepB-Hib vaccine is highly effective at preventing the diseases it targets. It provides long-lasting immunity and is considered safe for use in infants and young children.

Side effects

Like all vaccines, the DTwP-HepB-Hib vaccine can cause side effects, although they are generally mild and temporary. Common side effects include pain and swelling at the injection site, fever, and irritability.

See also

• Vaccination schedule
• Immunization

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  Prequalified pentavalent and years of sales to UNICEF
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  Pentavalent per-dose price ranges to UNICEF, 2005–2019