Isothipendyl

Isothipendyl is a first-generation H1-antihistamine that is used in the treatment of allergic conditions, including urticaria, rhinitis, and hay fever. It is also used as a sedative and to prevent or treat nausea and vomiting.

Pharmacology

Isothipendyl is a competitive antagonist of the histamine H1 receptor. It has sedative and antiemetic effects due to its action on the central nervous system. The drug also has anticholinergic properties, which can lead to side effects such as dry mouth and constipation.

Medical uses

Isothipendyl is used to treat a variety of allergic conditions, including urticaria, rhinitis, and hay fever. It can also be used as a sedative, or to prevent or treat nausea and vomiting.

Side effects

The most common side effects of isothipendyl are related to its anticholinergic effects, and include dry mouth, constipation, and blurred vision. Other side effects can include drowsiness, dizziness, and confusion.

Contraindications

Isothipendyl is contraindicated in patients with a known hypersensitivity to the drug. It should also be used with caution in patients with glaucoma, urinary retention, or prostate enlargement.

Interactions

Isothipendyl can interact with other medications, including other antihistamines, sedatives, and anticholinergic drugs. These interactions can increase the risk of side effects and should be considered when prescribing isothipendyl.

See also

• H1 antagonist
• Antihistamine
• Sedative

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  Chemical structure of Isothipendyl
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  Ball-and-stick model of Isothipendyl molecule