MDMB-4en-PINACA: Difference between revisions

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'''MDMB-4en-PINACA''' is a synthetic cannabinoid that has been identified in illicit products since 2019 and is sold as a designer drug. It is a potent agonist of the CB1 receptor, with a binding affinity of 0.094 nM, making it approximately 25 times more potent than THC.
{{DISPLAYTITLE:MDMB-4en-PINACA}}


== History ==
== MDMB-4en-PINACA ==
[[File:MDMB-4en-PINACA.svg|thumb|right|Chemical structure of MDMB-4en-PINACA]]
'''MDMB-4en-PINACA''' is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the [[cannabinoid receptor]]s, which are part of the [[endocannabinoid system]] in the human body. This compound is often found in "[[spice (drug)|spice]]" or "[[K2 (drug)|K2]]" products, which are marketed as legal alternatives to [[cannabis]].


[[MDMB-4en-PINACA]] was first identified in illicit products in 2019. It is a member of the [[synthetic cannabinoids]] family, which are a group of drugs that mimic the effects of [[cannabis]]. These substances have been associated with a number of adverse effects, including severe illness and death.
== Chemical Structure and Properties ==
MDMB-4en-PINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes a methyl ester group and a pentyl chain, which contribute to its high affinity for cannabinoid receptors. The compound is typically synthesized in clandestine laboratories and sold in various forms, including powders and herbal mixtures.


== Pharmacology ==
== Pharmacology ==
MDMB-4en-PINACA acts as a full agonist at the [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] receptors, which are primarily responsible for the psychoactive effects of cannabinoids. The activation of these receptors by MDMB-4en-PINACA can lead to effects similar to those of [[tetrahydrocannabinol]] (THC), the active component of cannabis, but often with greater potency and risk of adverse effects.


[[MDMB-4en-PINACA]] is a potent agonist of the [[CB1 receptor]], with a binding affinity of 0.094 nM. This makes it approximately 25 times more potent than [[THC]], the primary psychoactive compound in cannabis. The effects of MDMB-4en-PINACA in humans are largely unknown, as there is very little scientific research on this substance.
== Effects and Risks ==
The use of MDMB-4en-PINACA can result in a range of effects, including euphoria, altered perception, and relaxation. However, due to its high potency, it can also cause severe adverse effects such as [[tachycardia]], [[hypertension]], [[nausea]], [[vomiting]], [[anxiety]], [[paranoia]], and [[hallucinations]]. In some cases, it has been associated with [[seizures]] and [[acute kidney injury]].


== Legal status ==
== Legal Status ==
 
Due to its potential for abuse and lack of medical use, MDMB-4en-PINACA is classified as a controlled substance in many countries. It is often included in legislation targeting synthetic cannabinoids and other novel psychoactive substances.
As of 2020, MDMB-4en-PINACA is a controlled substance in several countries, including the United States, the United Kingdom, and Germany. It is also listed as a Schedule I substance under the United Nations Convention on Psychotropic Substances.
 
== See also ==


== Related Pages ==
* [[Synthetic cannabinoids]]
* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Cannabinoid receptor]]
* [[Endocannabinoid system]]
* [[Designer drug]]
* [[Designer drug]]
== References ==
<references />


[[Category:Synthetic cannabinoids]]
[[Category:Synthetic cannabinoids]]
[[Category:Designer drugs]]
[[Category:Designer drugs]]
[[Category:Controlled substances]]
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Latest revision as of 11:41, 15 February 2025


MDMB-4en-PINACA[edit]

Chemical structure of MDMB-4en-PINACA

MDMB-4en-PINACA is a synthetic cannabinoid that has been used as a designer drug. It is a potent agonist of the cannabinoid receptors, which are part of the endocannabinoid system in the human body. This compound is often found in "spice" or "K2" products, which are marketed as legal alternatives to cannabis.

Chemical Structure and Properties[edit]

MDMB-4en-PINACA is classified as an indazole-based synthetic cannabinoid. Its chemical structure includes a methyl ester group and a pentyl chain, which contribute to its high affinity for cannabinoid receptors. The compound is typically synthesized in clandestine laboratories and sold in various forms, including powders and herbal mixtures.

Pharmacology[edit]

MDMB-4en-PINACA acts as a full agonist at the CB1 and CB2 receptors, which are primarily responsible for the psychoactive effects of cannabinoids. The activation of these receptors by MDMB-4en-PINACA can lead to effects similar to those of tetrahydrocannabinol (THC), the active component of cannabis, but often with greater potency and risk of adverse effects.

Effects and Risks[edit]

The use of MDMB-4en-PINACA can result in a range of effects, including euphoria, altered perception, and relaxation. However, due to its high potency, it can also cause severe adverse effects such as tachycardia, hypertension, nausea, vomiting, anxiety, paranoia, and hallucinations. In some cases, it has been associated with seizures and acute kidney injury.

Legal Status[edit]

Due to its potential for abuse and lack of medical use, MDMB-4en-PINACA is classified as a controlled substance in many countries. It is often included in legislation targeting synthetic cannabinoids and other novel psychoactive substances.

Related Pages[edit]