Orbital lymphoma: Difference between revisions

Revision as of 11:21, 15 February 2025

Orbital Lymphoma

Orbital lymphoma is a type of non-Hodgkin lymphoma that occurs in the orbit, the bony cavity in the skull where the eye and its appendages are situated. It is a rare condition that can affect the eye socket, leading to various ocular and systemic symptoms.

Pathophysiology

Orbital lymphoma is characterized by the proliferation of malignant lymphocytes within the orbital tissues. The most common type of orbital lymphoma is mucosa-associated lymphoid tissue (MALT) lymphoma, but other types such as diffuse large B-cell lymphoma and follicular lymphoma can also occur.

Clinical Presentation

Patients with orbital lymphoma may present with a variety of symptoms, including:

Proptosis (bulging of the eye)
Diplopia (double vision)
Ptosis (drooping of the eyelid)
Vision impairment
Periorbital swelling

These symptoms result from the mass effect of the lymphoma within the confined space of the orbit.

Diagnosis

The diagnosis of orbital lymphoma typically involves:

Clinical examination
Imaging studies such as CT scan or MRI of the orbit
Biopsy of the orbital mass for histopathological examination

Treatment

Treatment options for orbital lymphoma depend on the type and stage of the lymphoma and may include:

In some cases, a combination of these treatments may be used to achieve the best outcome.

Prognosis

The prognosis for patients with orbital lymphoma varies depending on the type and stage of the disease. MALT lymphoma generally has a good prognosis with appropriate treatment, while more aggressive types like diffuse large B-cell lymphoma may have a more guarded prognosis.

Related Pages

@@ Line 1: / Line 1: @@
-'''Orbital lymphoma''' is a type of [[cancer]] that occurs in the [[lymphatic system]], specifically in the [[orbit (anatomy)|orbit]], the bony cavity containing the [[eye]]. It is a rare condition, accounting for only 1% of all [[lymphomas]], but it is the most common primary orbital malignancy.
+== Orbital Lymphoma ==
-== Symptoms ==
+[[File:Orbital_lymphoma.png|thumb|right|Orbital lymphoma affecting the eye socket]]
-The most common symptoms of orbital lymphoma include a noticeable mass or swelling in the eye area, [[diplopia]] (double vision), and [[proptosis]] (bulging of the eye). Other symptoms may include redness, pain, and impaired eye movement.
-== Causes ==
+'''Orbital lymphoma''' is a type of [[non-Hodgkin lymphoma]] that occurs in the [[orbit (anatomy)|orbit]], the bony cavity in the skull where the [[eye]] and its appendages are situated. It is a rare condition that can affect the [[eye socket]], leading to various ocular and systemic symptoms.
-The exact cause of orbital lymphoma is unknown. However, it is believed to be related to the body's immune response, and may be associated with certain [[autoimmune diseases]] and infections.
+== Pathophysiology ==
+Orbital lymphoma is characterized by the proliferation of malignant [[lymphocytes]] within the orbital tissues. The most common type of orbital lymphoma is [[mucosa-associated lymphoid tissue (MALT) lymphoma]], but other types such as [[diffuse large B-cell lymphoma]] and [[follicular lymphoma]] can also occur.
+== Clinical Presentation ==
+Patients with orbital lymphoma may present with a variety of symptoms, including:
+* [[Proptosis]] (bulging of the eye)
+* [[Diplopia]] (double vision)
+* [[Ptosis (eyelid)|Ptosis]] (drooping of the eyelid)
+* [[Vision impairment]]
+* [[Periorbital swelling]]
+These symptoms result from the mass effect of the lymphoma within the confined space of the orbit.
 == Diagnosis ==
-Diagnosis of orbital lymphoma typically involves a combination of [[medical history|history taking]], physical examination, imaging studies such as [[Computed tomography|CT]] or [[Magnetic resonance imaging|MRI]], and [[biopsy]] of the affected tissue.
+The diagnosis of orbital lymphoma typically involves:
+* [[Clinical examination]]
+* [[Imaging studies]] such as [[CT scan]] or [[MRI]] of the orbit
+* [[Biopsy]] of the orbital mass for histopathological examination
 == Treatment ==
-Treatment for orbital lymphoma usually involves [[radiation therapy]], [[chemotherapy]], or a combination of both. The choice of treatment depends on the stage and type of the lymphoma, as well as the patient's overall health.
+Treatment options for orbital lymphoma depend on the type and stage of the lymphoma and may include:
+* [[Radiation therapy]]
+* [[Chemotherapy]]
+* [[Immunotherapy]]
+In some cases, a combination of these treatments may be used to achieve the best outcome.
 == Prognosis ==
-The prognosis for orbital lymphoma is generally good, with a high rate of long-term survival. However, the prognosis can vary depending on the type and stage of the lymphoma, as well as the patient's overall health.
-== See also ==
+The prognosis for patients with orbital lymphoma varies depending on the type and stage of the disease. MALT lymphoma generally has a good prognosis with appropriate treatment, while more aggressive types like diffuse large B-cell lymphoma may have a more guarded prognosis.
+== Related Pages ==
 * [[Lymphoma]]
-* [[Orbit (anatomy)]]
+* [[Non-Hodgkin lymphoma]]
-* [[Eye neoplasm]]
+* [[Eye diseases]]
+* [[Ophthalmology]]
-[[Category:Oncology]]
 [[Category:Ophthalmology]]
-[[Category:Lymphatic system]]
+[[Category:Lymphoma]]
-{{stub}}