Nemonoxacin: Difference between revisions
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{{Short description|An encyclopedia article about the antibiotic Nemonoxacin}} | |||
== | ==Nemonoxacin== | ||
[[File:Nemonoxacin_structure.svg|thumb|right|Chemical structure of Nemonoxacin]] | |||
'''Nemonoxacin''' is a non-fluorinated [[quinolone]] antibiotic that is used to treat a variety of bacterial infections. It is particularly effective against [[Gram-positive bacteria]], including [[methicillin-resistant Staphylococcus aureus]] (MRSA) and [[Streptococcus pneumoniae]]. | |||
==Mechanism of Action== | ==Mechanism of Action== | ||
Nemonoxacin works by inhibiting | Nemonoxacin works by inhibiting bacterial [[DNA gyrase]] and [[topoisomerase IV]], enzymes that are essential for bacterial DNA replication, transcription, repair, and recombination. By interfering with these enzymes, nemonoxacin prevents the bacteria from multiplying and ultimately leads to bacterial cell death. | ||
== | ==Pharmacokinetics== | ||
Nemonoxacin has | Nemonoxacin is administered orally and is well absorbed from the gastrointestinal tract. It has a high bioavailability and is widely distributed throughout the body. The drug is primarily excreted unchanged in the urine, which makes it effective for treating urinary tract infections. | ||
==Clinical Uses== | |||
Nemonoxacin is used to treat a variety of infections, including: | |||
* [[Community-acquired pneumonia]] | |||
* [[Skin and soft tissue infections]] | |||
* [[Urinary tract infections]] | |||
==Side Effects== | ==Side Effects== | ||
Common side effects of nemonoxacin include [[nausea]], [[vomiting]], [[diarrhea]], and [[headache]]. Like other quinolones, it may also cause [[tendinitis]] and [[tendon rupture]], particularly in older adults and those taking corticosteroids. | |||
== | ==Development and Approval== | ||
Nemonoxacin was developed by [[TaiGen Biotechnology]] and has been approved for use in several countries, including [[Taiwan]] and [[China]]. It is currently undergoing clinical trials in other regions to expand its availability. | |||
==Related | ==Related pages== | ||
* [[Antibiotic]] | |||
* [[Quinolone]] | * [[Quinolone]] | ||
* [[ | * [[Bacterial infection]] | ||
[[Category:Antibiotics]] | [[Category:Antibiotics]] | ||
[[Category:Quinolones]] | [[Category:Quinolones]] | ||
Latest revision as of 11:06, 15 February 2025
An encyclopedia article about the antibiotic Nemonoxacin
Nemonoxacin[edit]
Nemonoxacin is a non-fluorinated quinolone antibiotic that is used to treat a variety of bacterial infections. It is particularly effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pneumoniae.
Mechanism of Action[edit]
Nemonoxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for bacterial DNA replication, transcription, repair, and recombination. By interfering with these enzymes, nemonoxacin prevents the bacteria from multiplying and ultimately leads to bacterial cell death.
Pharmacokinetics[edit]
Nemonoxacin is administered orally and is well absorbed from the gastrointestinal tract. It has a high bioavailability and is widely distributed throughout the body. The drug is primarily excreted unchanged in the urine, which makes it effective for treating urinary tract infections.
Clinical Uses[edit]
Nemonoxacin is used to treat a variety of infections, including:
Side Effects[edit]
Common side effects of nemonoxacin include nausea, vomiting, diarrhea, and headache. Like other quinolones, it may also cause tendinitis and tendon rupture, particularly in older adults and those taking corticosteroids.
Development and Approval[edit]
Nemonoxacin was developed by TaiGen Biotechnology and has been approved for use in several countries, including Taiwan and China. It is currently undergoing clinical trials in other regions to expand its availability.
