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Indophenol
== Indophenol ==


Indophenol is a class of synthetic dyes that are characterized by their vibrant blue or green colors. These compounds are used in various applications, including as pH indicators, in redox reactions, and in the food industry. The most well-known indophenol is 2,6-dichloroindophenol (DCIP), which is commonly used in laboratory settings to measure vitamin C content in food and biological samples.
[[File:Indophenol_Blue.svg|thumb|right|Chemical structure of Indophenol]]


== Chemical Structure and Properties ==
'''Indophenol''' is a synthetic dye that is commonly used as a redox indicator in various chemical reactions. It is known for its distinctive blue color in its oxidized form and is often used in titrations and other analytical chemistry applications.
Indophenols are typically derived from the reaction of phenols with aromatic amines in the presence of an oxidizing agent. The general structure of indophenols includes a phenolic group linked to an amine group through a quinonoid system, which is responsible for their color.


The chemical formula for 2,6-dichloroindophenol is C₁₂H₇Cl₂NO₂, and it has a molar mass of 268.10 g/mol. It appears as a dark blue or purple crystalline powder that is soluble in water and alcohol.
== Chemical Properties ==


== Applications ==
Indophenol is an organic compound with the chemical formula C<sub>12</sub>H<sub>9</sub>NO<sub>2</sub>. It is a member of the [[phenol]] family and contains both phenolic and amine functional groups. The compound is characterized by its ability to undergo reversible oxidation and reduction, which is the basis for its use as a redox indicator.


=== As a Redox Indicator ===
== Uses ==
Indophenols, particularly DCIP, are widely used as redox indicators in titrations. DCIP changes color from blue to colorless when reduced, making it useful for determining the concentration of reducing agents such as ascorbic acid (vitamin C).


=== In Vitamin C Analysis ===
Indophenol is primarily used in [[analytical chemistry]] as a redox indicator. It is particularly useful in titrations involving [[ascorbic acid]] (vitamin C), where it changes color from blue to colorless as it is reduced. This property makes it an effective tool for determining the concentration of ascorbic acid in various samples.
The most common application of DCIP is in the determination of vitamin C content in food and biological samples. The method involves titrating a solution of the sample with a DCIP solution until a persistent color change is observed, indicating the endpoint of the reaction.


=== In pH Indicators ===
== Synthesis ==
Some indophenols can also act as pH indicators due to their ability to change color with pH variations. This property is utilized in various chemical analyses and educational demonstrations.


== Synthesis ==
Indophenol can be synthesized through the reaction of [[phenol]] with [[nitrosobenzene]] in the presence of a base. This reaction results in the formation of the indophenol compound, which can then be isolated and purified for use in various applications.
The synthesis of indophenols typically involves the oxidative coupling of a phenol with an amine. For example, DCIP is synthesized by the reaction of 2,6-dichloroquinone with p-aminophenol in the presence of an oxidizing agent such as sodium hypochlorite.
 
== Related Compounds ==
 
Indophenol is related to other phenolic compounds and dyes, such as [[phenolphthalein]] and [[methylene blue]]. These compounds share similar properties and are often used in similar applications, particularly in the field of analytical chemistry.


== Safety and Handling ==
== Related Pages ==
Indophenols, like many synthetic dyes, should be handled with care. They can be irritants to the skin and eyes, and inhalation of dust should be avoided. Proper personal protective equipment, such as gloves and goggles, should be used when handling these compounds.


== Also see ==
* [[Redox indicator]]
* [[Redox indicator]]
* [[Vitamin C]]
* [[Phenol]]
* [[pH indicator]]
* [[Ascorbic acid]]
* [[Synthetic dyes]]
* [[Analytical chemistry]]
 
{{Chemical compounds}}
{{Dyes}}


[[Category:Chemical compounds]]
[[Category:Chemical compounds]]
[[Category:Dyes]]
[[Category:Dyes]]
[[Category:Indicators]]
[[Category:Redox indicators]]

Latest revision as of 10:48, 15 February 2025

Indophenol[edit]

Chemical structure of Indophenol

Indophenol is a synthetic dye that is commonly used as a redox indicator in various chemical reactions. It is known for its distinctive blue color in its oxidized form and is often used in titrations and other analytical chemistry applications.

Chemical Properties[edit]

Indophenol is an organic compound with the chemical formula C12H9NO2. It is a member of the phenol family and contains both phenolic and amine functional groups. The compound is characterized by its ability to undergo reversible oxidation and reduction, which is the basis for its use as a redox indicator.

Uses[edit]

Indophenol is primarily used in analytical chemistry as a redox indicator. It is particularly useful in titrations involving ascorbic acid (vitamin C), where it changes color from blue to colorless as it is reduced. This property makes it an effective tool for determining the concentration of ascorbic acid in various samples.

Synthesis[edit]

Indophenol can be synthesized through the reaction of phenol with nitrosobenzene in the presence of a base. This reaction results in the formation of the indophenol compound, which can then be isolated and purified for use in various applications.

Related Compounds[edit]

Indophenol is related to other phenolic compounds and dyes, such as phenolphthalein and methylene blue. These compounds share similar properties and are often used in similar applications, particularly in the field of analytical chemistry.

Related Pages[edit]