Proscaline: Difference between revisions

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'''Proscaline''' is a [[psychedelic]] [[phenethylamine]] of the [[2C family]]. It is closely related to [[mescaline]] and was first synthesized by [[Alexander Shulgin]].
== Proscaline ==


== History ==
[[File:Proscaline.svg|thumb|right|Chemical structure of Proscaline]]


Proscaline was first synthesized and investigated by Alexander Shulgin. In his book ''[[PiHKAL]]'', Shulgin lists the dosage range as 30 to 60 mg, consumed orally. The duration of proscaline is noted to be 8 to 12 hours.
'''Proscaline''' is a psychedelic compound of the phenethylamine class. It is chemically related to [[mescaline]], a naturally occurring psychedelic found in certain cacti. Proscaline is known for its psychoactive effects, which are similar to those of other phenethylamines, such as [[2C-B]] and [[2C-I]].


== Chemistry ==
=== Chemical Structure ===


Proscaline is a phenethylamine with a [[propyl]] group on the amine. It is structurally similar to mescaline, but has a three-carbon chain rather than a three-carbon ring.
Proscaline is a [[phenethylamine]], which means it has a basic structure consisting of a phenyl ring bound to an amino group through an ethyl chain. The chemical structure of proscaline is characterized by the presence of three methoxy groups attached to the phenyl ring, specifically at the 3, 4, and 5 positions. This structure is similar to that of mescaline, with the primary difference being the presence of a propoxy group at the 4-position in proscaline.


== Pharmacology ==
=== Pharmacology ===


Like other psychedelic phenethylamines, proscaline likely acts as a [[5-HT2A]] receptor [[agonist]]. However, the exact mechanism of action is not fully understood.
Proscaline acts primarily as a [[serotonin receptor]] agonist, particularly at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The activation of this receptor leads to altered perception, mood, and cognition, which are characteristic of psychedelic experiences. The compound may also interact with other serotonin receptors, contributing to its overall effects.


== Effects ==
=== Effects ===


The effects of proscaline are similar to those of other psychedelic phenethylamines. These can include [[hallucinations]], altered thinking processes, closed and open eye visuals, [[synesthesia]], an altered sense of time, and spiritual experiences. The effects are often described as being similar to those of mescaline, though with a significantly different duration and intensity.
The effects of proscaline are similar to those of other psychedelics, such as [[LSD]] and mescaline. Users report experiencing visual and auditory hallucinations, altered sense of time, and changes in thought patterns. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.


== Legal status ==
=== Legal Status ===


The legal status of proscaline varies by country. In the United States, it is not specifically listed as a controlled substance, but it may be considered an analog of a controlled substance under the [[Federal Analogue Act]].
The legal status of proscaline varies by country. In some jurisdictions, it is classified as a controlled substance, making its possession, sale, or use illegal. In other areas, it may not be specifically regulated, although it could still be subject to laws regarding analogs of controlled substances.


== See also ==
== Related Pages ==


* [[Mescaline]]
* [[Phenethylamine]]
* [[Phenethylamine]]
* [[Psychedelic drug]]
* [[Psychedelic drug]]
* [[PiHKAL]]
* [[Serotonin receptor]]
* [[Alexander Shulgin]]


[[Category:Psychedelic phenethylamines]]
[[Category:Psychedelic phenethylamines]]
[[Category:Psychedelic drugs]]
[[Category:Serotonin receptor agonists]]
[[Category:PiHKAL]]
{{Psychoactive drug-stub}}
{{Phenethylamines}}

Latest revision as of 04:06, 13 February 2025

Proscaline[edit]

Chemical structure of Proscaline

Proscaline is a psychedelic compound of the phenethylamine class. It is chemically related to mescaline, a naturally occurring psychedelic found in certain cacti. Proscaline is known for its psychoactive effects, which are similar to those of other phenethylamines, such as 2C-B and 2C-I.

Chemical Structure[edit]

Proscaline is a phenethylamine, which means it has a basic structure consisting of a phenyl ring bound to an amino group through an ethyl chain. The chemical structure of proscaline is characterized by the presence of three methoxy groups attached to the phenyl ring, specifically at the 3, 4, and 5 positions. This structure is similar to that of mescaline, with the primary difference being the presence of a propoxy group at the 4-position in proscaline.

Pharmacology[edit]

Proscaline acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor, which is believed to be responsible for its psychedelic effects. The activation of this receptor leads to altered perception, mood, and cognition, which are characteristic of psychedelic experiences. The compound may also interact with other serotonin receptors, contributing to its overall effects.

Effects[edit]

The effects of proscaline are similar to those of other psychedelics, such as LSD and mescaline. Users report experiencing visual and auditory hallucinations, altered sense of time, and changes in thought patterns. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal Status[edit]

The legal status of proscaline varies by country. In some jurisdictions, it is classified as a controlled substance, making its possession, sale, or use illegal. In other areas, it may not be specifically regulated, although it could still be subject to laws regarding analogs of controlled substances.

Related Pages[edit]