GR-113808: Difference between revisions

Latest revision as of 04:02, 13 February 2025

Cardiovascular System[edit]

Diagram of the human cardiovascular system

The cardiovascular system, also known as the circulatory system, is an organ system that permits blood to circulate and transport nutrients, oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.

Components[edit]

The cardiovascular system consists of the following major components:

Heart[edit]

The heart is a muscular organ that pumps blood through the blood vessels of the circulatory system. It is located in the thoracic cavity, between the lungs, and is divided into four chambers: the left and right atria and the left and right ventricles.

Blood Vessels[edit]

Blood vessels are the channels through which blood is distributed to body tissues. There are three major types of blood vessels:

Arteries - carry blood away from the heart.
Veins - carry blood back to the heart.
Capillaries - enable the exchange of water, oxygen, carbon dioxide, and many other nutrients and waste substances between blood and surrounding tissues.

Blood[edit]

Blood is a specialized bodily fluid that delivers necessary substances to the body's cells and transports waste products away from those same cells. It is composed of blood cells suspended in blood plasma.

Function[edit]

The primary function of the cardiovascular system is to transport nutrients, gases, and waste products around the body. It also plays a role in maintaining body temperature and pH balance.

Oxygen and Carbon Dioxide Transport[edit]

The cardiovascular system is responsible for the transport of oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs.

Nutrient and Waste Transport[edit]

Nutrients absorbed from the digestive tract are transported to the cells of the body, while waste products are transported to the kidneys for excretion.

Disorders[edit]

The cardiovascular system can be affected by a variety of disorders, including:

Hypertension - high blood pressure.
Atherosclerosis - buildup of fats, cholesterol, and other substances in and on the artery walls.
Heart attack - occurs when blood flow to a part of the heart is blocked for a long enough time that part of the heart muscle is damaged or dies.

Related Pages[edit]

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-'''GR-113808''' is a [[serotonin]] [[receptor antagonist]] that is used in scientific research. It is most commonly used in studies involving the [[gastrointestinal tract]], as it has a high affinity for the [[5-HT4 receptor]], a type of serotonin receptor that is found in high concentrations in the gastrointestinal tract.
+== Cardiovascular System ==
-== Mechanism of Action ==
+[[File:GR-113808.svg|thumb|right|Diagram of the human cardiovascular system]]
-GR-113808 works by binding to the 5-HT4 receptor and preventing serotonin from activating it. This can have a variety of effects, depending on the specific function of the 5-HT4 receptor in the tissue where it is located. In the gastrointestinal tract, for example, blocking the 5-HT4 receptor can slow down the movement of food through the digestive system.
+The '''cardiovascular system''', also known as the '''circulatory system''', is an organ system that permits blood to circulate and transport nutrients, oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
-== Use in Research ==
+== Components ==
-Due to its high affinity for the 5-HT4 receptor, GR-113808 is often used in research studies that are investigating the role of this receptor in various physiological processes. For example, it has been used in studies looking at the role of the 5-HT4 receptor in the regulation of [[gastric motility]] and [[intestinal secretion]].
+The cardiovascular system consists of the following major components:
-== Side Effects ==
+=== Heart ===
-As with any drug, GR-113808 can have side effects. These can vary depending on the dose and the individual, but may include [[nausea]], [[vomiting]], and [[abdominal pain]]. It is important to note that these side effects are usually mild and temporary.
+The [[heart]] is a muscular organ that pumps blood through the blood vessels of the circulatory system. It is located in the thoracic cavity, between the lungs, and is divided into four chambers: the left and right atria and the left and right ventricles.
-== See Also ==
+=== Blood Vessels ===
-* [[5-HT4 receptor]]
+Blood vessels are the channels through which blood is distributed to body tissues. There are three major types of blood vessels:
-* [[Serotonin]]
-* [[Receptor antagonist]]
-== References ==
+* '''[[Arteries]]''' - carry blood away from the heart.
+* '''[[Veins]]''' - carry blood back to the heart.
+* '''[[Capillaries]]''' - enable the exchange of water, oxygen, carbon dioxide, and many other nutrients and waste substances between blood and surrounding tissues.
-<references />
+=== Blood ===
-[[Category:Serotonin antagonists]]
+[[Blood]] is a specialized bodily fluid that delivers necessary substances to the body's cells and transports waste products away from those same cells. It is composed of blood cells suspended in blood plasma.
-[[Category:Research chemicals]]
-[[Category:Gastrointestinal drugs]]
-{{medicine-stub}}
+== Function ==
+The primary function of the cardiovascular system is to transport nutrients, gases, and waste products around the body. It also plays a role in maintaining body temperature and pH balance.
+=== Oxygen and Carbon Dioxide Transport ===
+The cardiovascular system is responsible for the transport of oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs.
+=== Nutrient and Waste Transport ===
+Nutrients absorbed from the digestive tract are transported to the cells of the body, while waste products are transported to the kidneys for excretion.
+== Disorders ==
+The cardiovascular system can be affected by a variety of disorders, including:
+* '''[[Hypertension]]''' - high blood pressure.
+* '''[[Atherosclerosis]]''' - buildup of fats, cholesterol, and other substances in and on the artery walls.
+* '''[[Heart attack]]''' - occurs when blood flow to a part of the heart is blocked for a long enough time that part of the heart muscle is damaged or dies.
+== Related Pages ==
+* [[Respiratory system]]
+* [[Endocrine system]]
+* [[Nervous system]]
+[[Category:Cardiovascular system]]