TCB-2: Difference between revisions

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'''TCB-2''' is a [[psychedelic drug]] that was first synthesized by [[Alexander Shulgin]]. It is a potent and selective [[partial agonist]] for the [[serotonin]] [[5-HT2A receptor]], and is thought to be a research chemical that has been sold online as a [[designer drug]].
== TCB-2 ==


==Chemistry==
[[File:TCB-2.png|thumb|right|Chemical structure of TCB-2]]
TCB-2 is a member of the [[25-NB family]]. It is structurally related to [[2C-B]] and [[DOB]], with the 4-bromo group of 2C-B replaced by a 4-chloro group, and the 2,5-dimethoxy groups of DOB replaced by 2,5-dichloro groups.


==Pharmacology==
'''TCB-2''' is a synthetic compound that acts as a potent [[psychedelic]] drug. It is a member of the [[phenethylamine]] class of chemicals and is known for its strong [[serotonin receptor]] agonist properties, particularly at the [[5-HT2A receptor]].
TCB-2 is a [[partial agonist]] at the [[5-HT2A receptor]]. It has a high affinity for this receptor, with a [[Ki]] of 0.25 nM. This makes it around 6 times more potent than [[DOB]], and slightly less potent than [[LSD]].  


==Effects==
=== Chemical Structure ===
The effects of TCB-2 are not well documented, as it is a relatively new substance. However, it is thought to produce effects similar to other [[psychedelic drugs]], such as [[visual hallucinations]], [[altered perception]], and [[euphoria]].


==Legal Status==
TCB-2 is chemically related to other phenethylamines such as [[2C-B]] and [[2C-I]]. Its full chemical name is 2,5-dimethoxy-4-bromoamphetamine. The presence of the bromine atom in its structure is a key feature that contributes to its pharmacological activity.
In the United States, TCB-2 is not specifically listed as a controlled substance, but it may be considered an analog of 2C-B or DOB, which are Schedule I drugs under the [[Controlled Substances Act]].


==See Also==
=== Pharmacology ===
* [[25-NB]]
 
* [[2C-B]]
TCB-2 primarily acts as an agonist at the 5-HT2A receptor, which is a subtype of the [[serotonin receptor]]. This receptor is known to play a significant role in the modulation of mood, perception, and cognition. The activation of 5-HT2A receptors by TCB-2 is believed to be responsible for its psychedelic effects.
* [[DOB]]
 
* [[LSD]]
=== Effects ===
* [[Psychedelic drug]]
 
* [[Designer drug]]
The effects of TCB-2 are similar to those of other psychedelics, such as [[LSD]] and [[psilocybin]]. Users report altered states of consciousness, visual and auditory hallucinations, and changes in perception of time and space. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.
 
=== Legal Status ===
 
The legal status of TCB-2 varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is important for researchers and users to be aware of the legal implications of possessing or using TCB-2.
 
=== Research ===


==References==
TCB-2 has been used in scientific research to study the role of the 5-HT2A receptor in the brain. It serves as a tool for understanding the mechanisms underlying psychedelic experiences and has potential applications in the study of [[mental health]] disorders such as [[depression]] and [[anxiety]].
<references />


[[Category:Psychedelic drugs]]
== Related pages ==
[[Category:Designer drugs]]
* [[Psychedelic drug]]
[[Category:Research chemicals]]
* [[Serotonin receptor]]
[[Category:Serotonin receptor agonists]]
* [[Phenethylamine]]
* [[2C-B]]
* [[5-HT2A receptor]]


{{stub}}
[[Category:Psychedelic phenethylamines]]

Latest revision as of 03:26, 13 February 2025

TCB-2[edit]

Chemical structure of TCB-2

TCB-2 is a synthetic compound that acts as a potent psychedelic drug. It is a member of the phenethylamine class of chemicals and is known for its strong serotonin receptor agonist properties, particularly at the 5-HT2A receptor.

Chemical Structure[edit]

TCB-2 is chemically related to other phenethylamines such as 2C-B and 2C-I. Its full chemical name is 2,5-dimethoxy-4-bromoamphetamine. The presence of the bromine atom in its structure is a key feature that contributes to its pharmacological activity.

Pharmacology[edit]

TCB-2 primarily acts as an agonist at the 5-HT2A receptor, which is a subtype of the serotonin receptor. This receptor is known to play a significant role in the modulation of mood, perception, and cognition. The activation of 5-HT2A receptors by TCB-2 is believed to be responsible for its psychedelic effects.

Effects[edit]

The effects of TCB-2 are similar to those of other psychedelics, such as LSD and psilocybin. Users report altered states of consciousness, visual and auditory hallucinations, and changes in perception of time and space. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal Status[edit]

The legal status of TCB-2 varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and lack of medical use. It is important for researchers and users to be aware of the legal implications of possessing or using TCB-2.

Research[edit]

TCB-2 has been used in scientific research to study the role of the 5-HT2A receptor in the brain. It serves as a tool for understanding the mechanisms underlying psychedelic experiences and has potential applications in the study of mental health disorders such as depression and anxiety.

Related pages[edit]