Aromadendrin: Difference between revisions

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'''Aromadendrin''' (also known as '''picein''') is a flavanonol, a type of flavonoid. It is found in the bark of [[Picea sitchensis]] (Sitka spruce) and in the fern [[Notholaena nivea]]. It has also been isolated from the [[petal]]s of [[Prunus avium]] (sweet cherry) and the [[wine]] of [[Vitis vinifera]] (grape vine).
{{short description|A flavanonol, a type of flavonoid}}
{{Chembox
| verifiedrevid = 443418007
| ImageFile = Aromadendrin.svg
| ImageSize = 200px
| IUPACName = (2R,3R)-3,5,7-Trihydroxy-2-(4-hydroxyphenyl)chroman-4-one
| OtherNames = Dihydrokaempferol
| Section1 = {{Chembox Identifiers
  | CASNo = 480-20-6
  | PubChem = 5280677
  | ChemSpiderID = 4445010
  | UNII = 0F3K9Q464I
  | ChEMBL = 1234567
  | SMILES = C1=CC(=CC=C1C2C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O
  | InChI = 1S/C15H12O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-9(17)5-10(18)6-11(12)21-15/h1-6,15-18,20H
  | InChIKey = YXJYVIAFUVLZSU-UHFFFAOYSA-N
}}
| Section2 = {{Chembox Properties
  | C=15
  | H=12
  | O=6
  | MolarMass = 288.25 g/mol
}}
}}


==Chemical Structure==
'''Aromadendrin''' is a type of [[flavanonol]], a subclass of [[flavonoids]], which are naturally occurring compounds with various biological activities. Aromadendrin is also known as '''dihydrokaempferol'''.
Aromadendrin has a chemical formula of C15H12O6. It is a flavanonol, which is a subclass of flavonoids. Flavonoids are a class of plant secondary metabolites. Aromadendrin is a yellow crystalline solid that is soluble in [[ethanol]] and [[methanol]], but insoluble in water.


==Natural Occurrence==
==Structure and Properties==
Aromadendrin is found in several plant species. It is present in the bark of [[Picea sitchensis]] (Sitka spruce), a tree native to the west coast of North America. It is also found in the fern [[Notholaena nivea]], which is native to the southwestern United States and northern Mexico. Additionally, aromadendrin has been isolated from the petals of [[Prunus avium]] (sweet cherry) and the wine of [[Vitis vinifera]] (grape vine).
Aromadendrin is characterized by its chemical structure, which includes a chroman-4-one backbone with hydroxyl groups at positions 3, 5, and 7, and an additional hydroxyl group on the phenyl ring. This structure contributes to its antioxidant properties, as the hydroxyl groups can donate hydrogen atoms to neutralize free radicals.


==Health Benefits==
==Occurrence==
Research has suggested that aromadendrin has several potential health benefits. It has been found to have anti-inflammatory and antioxidant properties. It may also have potential as a treatment for [[diabetes]] due to its ability to inhibit alpha-glucosidase, an enzyme that breaks down carbohydrates into glucose.
Aromadendrin is found in various plant species, including those in the [[Pinaceae]] family. It is present in the leaves, bark, and wood of these plants. The compound is often extracted for its potential health benefits and use in research.


==Safety and Toxicity==
==Biological Activity==
While aromadendrin is generally considered safe, it may cause allergic reactions in some individuals. As with any supplement, it is recommended to consult with a healthcare provider before use.
Aromadendrin exhibits several biological activities, including antioxidant, anti-inflammatory, and antimicrobial effects. These properties make it a subject of interest in the development of therapeutic agents. Its antioxidant activity is particularly significant, as it helps in protecting cells from oxidative stress, which is implicated in various diseases.


==See Also==
==Potential Health Benefits==
Research suggests that aromadendrin may have potential health benefits, such as reducing inflammation and protecting against certain chronic diseases. Its ability to scavenge free radicals and modulate inflammatory pathways is being explored in the context of cardiovascular health, neuroprotection, and cancer prevention.
 
==Synthesis and Derivatives==
Aromadendrin can be synthesized through various chemical reactions, including the reduction of [[kaempferol]]. It serves as a precursor for other flavonoids and can be modified to enhance its biological activity or solubility.
 
==Related Compounds==
Aromadendrin is related to other flavonoids such as [[kaempferol]], [[quercetin]], and [[catechin]]. These compounds share similar structural features and biological activities, contributing to their roles in plant defense and human health.
 
==See also==
* [[Flavonoid]]
* [[Flavonoid]]
* [[Picea sitchensis]]
* [[Antioxidant]]
* [[Notholaena nivea]]
* [[Phytochemistry]]
* [[Prunus avium]]
 
* [[Vitis vinifera]]
==Gallery==
<gallery>
File:Cortical_surface_with_an_overlay_of_the_basal_ganglia_and_thalamus.jpg|Cortical surface with an overlay of the basal ganglia and thalamus
</gallery>


{{Chemical-compound-stub}}
[[Category:Flavanonols]]
[[Category:Flavanonols]]
[[Category:Phytochemicals]]
[[Category:Flavonoids]]
[[Category:Natural phenols]]
[[Category:Antioxidants]]
[[Category:Flavonoids found in food]]

Revision as of 17:50, 11 February 2025

A flavanonol, a type of flavonoid


Chemical Compound
Identifiers
CAS Number
PubChem CID
ChemSpider ID
UNII
ChEBI
ChEMBL
Properties
Chemical Formula
Molar Mass
Appearance
Density
Melting Point
Boiling Point
Hazards
GHS Pictograms [[File:|50px]]
GHS Signal Word
GHS Hazard Statements
NFPA 704 [[File:|50px]]
References

Aromadendrin is a type of flavanonol, a subclass of flavonoids, which are naturally occurring compounds with various biological activities. Aromadendrin is also known as dihydrokaempferol.

Structure and Properties

Aromadendrin is characterized by its chemical structure, which includes a chroman-4-one backbone with hydroxyl groups at positions 3, 5, and 7, and an additional hydroxyl group on the phenyl ring. This structure contributes to its antioxidant properties, as the hydroxyl groups can donate hydrogen atoms to neutralize free radicals.

Occurrence

Aromadendrin is found in various plant species, including those in the Pinaceae family. It is present in the leaves, bark, and wood of these plants. The compound is often extracted for its potential health benefits and use in research.

Biological Activity

Aromadendrin exhibits several biological activities, including antioxidant, anti-inflammatory, and antimicrobial effects. These properties make it a subject of interest in the development of therapeutic agents. Its antioxidant activity is particularly significant, as it helps in protecting cells from oxidative stress, which is implicated in various diseases.

Potential Health Benefits

Research suggests that aromadendrin may have potential health benefits, such as reducing inflammation and protecting against certain chronic diseases. Its ability to scavenge free radicals and modulate inflammatory pathways is being explored in the context of cardiovascular health, neuroprotection, and cancer prevention.

Synthesis and Derivatives

Aromadendrin can be synthesized through various chemical reactions, including the reduction of kaempferol. It serves as a precursor for other flavonoids and can be modified to enhance its biological activity or solubility.

Related Compounds

Aromadendrin is related to other flavonoids such as kaempferol, quercetin, and catechin. These compounds share similar structural features and biological activities, contributing to their roles in plant defense and human health.

See also

Gallery

  • Cortical surface with an overlay of the basal ganglia and thalamus
    Cortical surface with an overlay of the basal ganglia and thalamus
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